5027 |
PURINERGIC RECEPTOR P2X 7 |
P2RX7 |
P2X7 |
602566 |
8537 |
ENSG00000089041 |
OTTHUMG00000169153 |
P2X purinoceptor 7 |
Purinergic receptor |
P2Z receptor |
ATP receptor |
Q99572 |
P2RX7_HUMAN |
P2X PURINOCEPTOR 7 (ATP RECEPTOR) (P2X7) (PURINERGIC RECEPTOR) (P2Z RECEPTOR). [SOURCE:UNIPROT/SWISSPROT;ACC:Q99572] |
PA32866 |
T63414 |
Target Class | Receptors |
Target Subclass | TC:1.A.7.1.3 |
Human Readable Name | DRUGGABLE GENOME |
Interpro Type | Family |
Uniprot Status | Swiss-Prot |
Interpro Name | P2X purinoreceptor |
Uniprot Evidence | 1: Evidence at protein level |
Interpro Short Name | P2X_purnocptor |
Interpro Acc | IPR001429 |
Gene Biotype | PROTEIN_CODING |
ION CHANNEL |
NUCLEAR HORMONE RECEPTOR |
EXTERNAL SIDE OF PLASMA MEMBRANE |
DRUGGABLE GENOME |
antagonist (inhibitory) |
Mechanism of Interaction | P2X purinoceptor 7 antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | P2X purinoceptor 7 antagonist |
Direct Interaction | yes |
Trial Name | EVT-401 |
antagonist (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | P2X purinoceptor 7 antagonist |
allosteric modulator |
antagonist (inhibitory) |
Mechanism of Interaction | P2X purinoceptor 7 negative allosteric modulator |
Direct Interaction | yes |
P2RX7 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
P2RX7 | Gene Symbol |
Target Class | Receptors |
Target Subclass | TC:1.A.7.1.3 |
P2X PURINOCEPTOR 7 (ATP RECEPTOR) (P2X7) (PURINERGIC RECEPTOR) (P2Z RECEPTOR). [SOURCE:UNIPROT/SWISSPROT;ACC:Q99572] | Description |
ENSG00000089041 | Ensembl Gene Id |
P2RX7 | Display Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
ENSG00000089041 | Ensembl Gene Id |
Q99572 | Uniprot Accession |
P2X PURINOCEPTOR 7 | Uniprot Protein Name |
Human Readable Name | DRUGGABLE GENOME |
Interpro Type | Family |
Uniprot Status | Swiss-Prot |
DRUGGABLE GENOME |
P2RX7 | TTD Gene Abbreviation |
T63414 | TTD Target ID |
P2RX7 | GENE_SYMBOL |
P2X purinoceptor 7 | UNIPROT |
ATP receptor | UNIPROT |
ENSG00000089041 | Gene Symbol |
P2RX7 | Ensembl Id |
DRUGGABLE GENOME |
PA32866 | PharmGKB ID |
P2X purinoceptor 7 | Gene Name |
Q99572 | UniProt ID |
ION CHANNEL, NUCLEAR HORMONE RECEPTOR |
EXTERNAL SIDE OF PLASMA MEMBRANE |