PARP3 Gene Record

  • CHEMBL380648   PARP3

    Interaction Score: 18.55

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    19354255 10592235


    Sources:
    DTC

  • RUCAPARIB CAMSYLATE   PARP3

    Interaction Score: 4.12

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction PARP 1, 2 and 3 inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • VELIPARIB   PARP3

    Interaction Score: 1.24

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction PARP 1, 2 and 3 inhibitor

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • OLAPARIB   PARP3

    Interaction Score: 0.92

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction PARP 1, 2 & 3 inhibitor
    Direct Interaction yes

    PMIDs:
    25981132


    Sources:
    ChemblInteractions

  • RUCAPARIB   PARP3

    Interaction Score: 0.75

    Interaction Types & Directionality:
    antagonist (inhibitory)
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction PARP 1, 2 and 3 inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions PharmGKB

  • Ensembl: ENSG00000041880

    • Version: 101_38

    Alternate Names:
    PARP3 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • RussLampel: ENSG00000041880

    • Version: 26-July-2011

    Alternate Names:
    PARP3 Display Id
    ENSG00000041880 Ensembl Gene Id
    POLY [ADP-RIBOSE] POLYMERASE-3 (EC 2.4.2.30) (PARP-3) (NAD(+) ADP- RIBOSYLTRANSFERASE-3) (POLY[ADP-RIBOSE] SYNTHETASE-3) (PADPRT-3) (HPARP-3) (IRT1). [SOURCE:UNIPROT/SWISSPROT;ACC:Q9Y6F1] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HopkinsGroom: Q9Y6F1

    • Version: 11-September-2012

    Alternate Names:
    POLY [ADP-RIBOSE] POLYMERASE 3 Uniprot Protein Name
    Q9Y6F1 Uniprot Accession
    10039 Entrez Gene Id

    Gene Info:
    Uniprot Status Swiss-Prot
    Interpro Acc IPR012317
    Uniprot Evidence 1: Evidence at protein level

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • DTC: PARP3

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Lehtiö L et al., 2009, Structural basis for inhibitor specificity in human poly(ADP-ribose) polymerase-3., J Med Chem

  • HingoraniCasas: ENSG00000041880

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000041880 Gene Symbol
    PARP3 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • ChemblInteractions: ADPRT3

    • Version: chembl_23

    Alternate Names:
    ADPRTL3 GENE_SYMBOL
    PARP3 GENE_SYMBOL
    Poly [ADP-ribose] polymerase 3 UNIPROT

    Gene Info:

    Publications:

  • PharmGKB: PARP3

    • Version: 18-August-2020

    Alternate Names:
    PA24593 PharmGKB ID

    Gene Info:

    Publications:

  • GO: PARP3

    • Version: 01-February-2022

    Alternate Names:
    ADPRT3 GO Gene Synonym
    ADPRTL3 GO Gene Synonym

    Gene Info:

    Gene Categories:
    DNA REPAIR

    Publications:

  • TTD: Poly [ADP-ribose] polymerase 3

    • Version: 2020.06.01

    Alternate Names:
    PARP3 TTD Gene Abbreviation
    T17228 TTD Target ID

    Gene Info:

    Publications:

  • Pharos: PARP3

    • Version: 01-February-2022

    Alternate Names:
    Poly [ADP-ribose] polymerase 3 Gene Name
    Q9Y6F1 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

  • FoundationOneGenes: PARP3

    • Version: 03-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications: