PBK Gene Record

  • PBK 55872 Druggable GenomeDrug Resistance

    Alternate Names:

    55872
    PDZ BINDING KINASE
    PBK
    CT84
    HEL164
    Nori-3
    SPK
    TOPK
    611210
    18282
    ENSG00000168078
    OTTHUMG00000102113
    T-LYMPHOKINE-ACTIVATED KILLER CELL-ORIGINATED PROTEIN KINASE (EC 2.7.1.37) (T-LAK CELL-ORIGINATED PROTEIN KINASE) (PDZ-BINDING KINASE) (SPERMATOGENESIS-RELATED PROTEIN KINASE) (SPK) (MAPKK-LIKE PROTEIN KINASE) (NORI-3). [SOURCE:UNIPROT/SWISSPROT;ACC:Q96KB
    Q96KB5
    13276
    Lymphokine-activated killer T-cell-originated protein kinase

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Gene Biotype PROTEIN_CODING
    (4 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    TYROSINE KINASE
    DRUG RESISTANCE
    DRUGGABLE GENOME

    Publications:

  • GEFITINIB   PBK

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    26745678


    Sources:
    CIViC

  • CHEMBL541400   PBK

    Interaction Score: 0.33

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL225519   PBK

    Interaction Score: 0.19

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • LINIFANIB   PBK

    Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • SP-600125   PBK

    Interaction Score: 0.14

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Ensembl: ENSG00000168078

    • Version: 101_38

    Alternate Names:
    PBK Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • RussLampel: ENSG00000168078

    • Version: 26-July-2011

    Alternate Names:
    T-LYMPHOKINE-ACTIVATED KILLER CELL-ORIGINATED PROTEIN KINASE (EC 2.7.1.37) (T-LAK CELL-ORIGINATED PROTEIN KINASE) (PDZ-BINDING KINASE) (SPERMATOGENESIS-RELATED PROTEIN KINASE) (SPK) (MAPKK-LIKE PROTEIN KINASE) (NORI-3). [SOURCE:UNIPROT/SWISSPROT;ACC:Q96KB Description
    PBK Display Id
    ENSG00000168078 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • CIViC: PBK

    • Version: 14-September-2020

    Alternate Names:
    55872 Entrez Gene ID
    13276 CIViC Gene ID

    Gene Info:

    Gene Categories:
    DRUG RESISTANCE

    Publications:
    Li et al., 2016, TOPK promotes lung cancer resistance to EGFR tyrosine kinase inhibitors by phosphorylating and activating c-Jun., Oncotarget

  • HingoraniCasas: ENSG00000168078

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000168078 Gene Symbol
    PBK Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • GO: PBK

    • Version: 01-February-2022

    Alternate Names:
    TOPK GO Gene Synonym

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE, TYROSINE KINASE

    Publications:

  • dGene: PBK

    • Version: 27-Jun-2013

    Alternate Names:
    55872 Gene ID
    CT84 dGene Synonym
    Nori-3 dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

  • Pharos: PBK

    • Version: 01-February-2022

    Alternate Names:
    Lymphokine-activated killer T-cell-originated protein kinase Gene Name
    Q96KB5 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

  • DTC: PBK

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications: