PDCD1 Gene Record

  • PIDILIZUMAB   PDCD1

    Interaction Score: 6.62

    Interaction Types & Directionality:
    antibody (inhibitory)

    Interaction Info:
    Reported Cancer Type Melanoma
    Trial Name CT-011
    Novel drug target Novel Target

    PMIDs:
    None found


    Sources:
    MyCancerGenome TdgClinicalTrial CancerCommons

  • CEMIPLIMAB   PDCD1

    Interaction Score: 6.62

    Interaction Types & Directionality:
    antibody (inhibitory)
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    29863979 29089720


    Sources:
    TTD

  • MGA-012   PDCD1

    Interaction Score: 4.42

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • DOSTARLIMAB   PDCD1

    Interaction Score: 4.42

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • SINTILIMAB   PDCD1

    Interaction Score: 4.42

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • SYM-021   PDCD1

    Interaction Score: 4.42

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • SPARTALIZUMAB   PDCD1

    Interaction Score: 4.42

    Interaction Types & Directionality:
    antibody (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • SASANLIMAB   PDCD1

    Interaction Score: 4.42

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • BALSTILIMAB   PDCD1

    Interaction Score: 4.42

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • AMP-224   PDCD1

    Interaction Score: 4.42

    Interaction Types & Directionality:
    antibody (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome TTD

  • TISLELIZUMAB   PDCD1

    Interaction Score: 4.42

    Interaction Types & Directionality:
    antibody (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • NIVOLUMAB   PDCD1

    Interaction Score: 1.77

    Interaction Types & Directionality:
    antibody (inhibitory)
    inhibitor (inhibitory)

    Interaction Info:
    Novel drug target Novel Target
    Trial Name BMS-936558, ONO-4538, MDX-1106
    Direct Interaction yes

    PMIDs:
    23289116


    Sources:
    MyCancerGenome TdgClinicalTrial ClearityFoundationClinicalTrial ChemblInteractions TTD

  • M-7824   PDCD1

    Interaction Score: 1.47

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • PEMBROLIZUMAB   PDCD1

    Interaction Score: 0.8

    Interaction Types & Directionality:
    antibody (inhibitory)
    antagonist (inhibitory)
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Programmed cell death protein 1 inhibitor
    Direct Interaction yes

    PMIDs:
    25685857


    Sources:
    MyCancerGenome ChemblInteractions TTD

  • Ensembl: ENSG00000188389

    • Version: 101_38

    Alternate Names:
    PDCD1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • TdgClinicalTrial: Q15116

    • Version: January-2014

    Alternate Names:
    PDCD1 Gene Symbol

    Gene Info:
    Target Class Receptors
    Target Subclass Miscellaneous
    Target Subclass PDCD1

    Publications:

  • CancerCommons: PDCD1

    • Version: 25-July-2013

    Alternate Names:
    5133 Entrez Gene ID

    Gene Info:
    CancerCommons Reported Gene Name Anti-PD-1

    Publications:

  • MyCancerGenome: PDCD1

    • Version: 20-Jun-2017

    Alternate Names:
    5133 Entrez Gene Id
    PDCD1 MyCancerGenome Gene Symbol
    PD-1 MyCancerGenome Reported Gene Name

    Gene Info:

    Publications:

  • HingoraniCasas: ENSG00000188389

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000188389 Gene Symbol
    PDCD1 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • ChemblInteractions: PD1

    • Version: chembl_23

    Alternate Names:
    PD1 GENE_SYMBOL
    PDCD1 GENE_SYMBOL
    Programmed cell death protein 1 UNIPROT

    Gene Info:

    Publications:

  • GO: PDCD1

    • Version: 01-February-2022

    Alternate Names:
    PD1 GO Gene Synonym

    Gene Info:

    Gene Categories:
    EXTERNAL SIDE OF PLASMA MEMBRANE

    Publications:

  • Tempus: PDCD1

    • Version: 11-November-2018

    Alternate Names:
    PDCD1 Gene Symbol

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • TTD: Programmed cell death protein 1

    • Version: 2020.06.01

    Alternate Names:
    PD-1 TTD Gene Abbreviation
    T59631 TTD Target ID

    Gene Info:

    Publications:

  • ClearityFoundationClinicalTrial: PDCD1

    • Version: 15-June-2013

    Alternate Names:

    Gene Info:

    Publications:

  • MskImpact: PDCD1

    • Version: May-2015

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • FoundationOneGenes: PDCD1

    • Version: 03-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • CarisMolecularIntelligence: PDCD1

    • Version: 04-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications: