5139 |
PHOSPHODIESTERASE 3A |
PDE3A |
CGI-PDE |
CGI-PDE A |
CGI-PDE-A |
HTNB |
123805 |
8778 |
ENSG00000172572 |
OTTHUMG00000168962 |
Q14432 |
PDE3A_HUMAN |
PDE3 |
PHOSPHODIESTERASE 3 |
CGMP-INHIBITED 3',5'-CYCLIC PHOSPHODIESTERASE A |
Cyclic GMP-inhibited phosphodiesterase A |
CGMP-INHIBITED 3',5'-CYCLIC PHOSPHODIESTERASE A (EC 3.1.4.17) (CYCLIC GMP INHIBITED PHOSPHODIESTERASE A) (CGI-PDE A). [SOURCE:UNIPROT/SWISSPROT;ACC:Q14432] |
PA33126 |
T33754 |
T88975 |
Target Subclass | 3.1.4 |
Transmembrane Helix Count | 6 |
Target Main Class | Enzymes |
Target Class | Enzymes |
Target Subclass | EC:3.1.4 |
Target Subclass | EC:3.1.4.17 |
Uniprot Status | Swiss-Prot |
Human Readable Name | DRUGGABLE GENOME |
Interpro Type | Domain |
Interpro Short Name | PDEase_catalytic_dom |
Interpro Acc | IPR002073 |
Uniprot Evidence | 1: Evidence at protein level |
Interpro Name | 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain |
Gene Biotype | PROTEIN_CODING |
DRUGGABLE GENOME |
ENZYME |
inhibitor (inhibitory) |
Novel drug target | Established target |
Trial Name | - |
inhibitor (inhibitory) |
Mechanism of Interaction | Phosphodiesterase 3A inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Phosphodiesterase 3A inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Phosphodiesterase 3A inhibitor |
Direct Interaction | yes |
Trial Name | - |
inhibitor (inhibitory) |
Mechanism of Interaction | Phosphodiesterase 3 inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Phosphodiesterase 3 inhibitor |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Phosphodiesterase 3 inhibitor |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Phosphodiesterase 3 inhibitor |
Trial Name | ADC4022, low-dose inhaled theophylline |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Phosphodiesterase 3A inhibitor |
inhibitor (inhibitory) |
Mechanism of Interaction | Phosphodiesterase 3 inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | 3',5'-cyclic phosphodiesterase inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | 3',5'-cyclic phosphodiesterase inhibitor |
Direct Interaction | yes |
PDE3A | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
PDE3A | Display Id |
CGMP-INHIBITED 3',5'-CYCLIC PHOSPHODIESTERASE A (EC 3.1.4.17) (CYCLIC GMP INHIBITED PHOSPHODIESTERASE A) (CGI-PDE A). [SOURCE:UNIPROT/SWISSPROT;ACC:Q14432] | Description |
ENSG00000172572 | Ensembl Gene Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
PDE3A_HUMAN | Uniprot Id |
PDE3A | Gene Symbol |
ENSG00000172572 | Ensembl Gene Id |
Target Subclass | 3.1.4 |
Transmembrane Helix Count | 6 |
Target Main Class | Enzymes |
PDE3A | Gene Symbol |
Target Class | Enzymes |
Target Subclass | EC:3.1.4 |
Target Subclass | EC:3.1.4.17 |
PDE3A_HUMAN | Uniprot Id |
5139 | Entrez Gene Id |
PDE3A | Uniprot Gene Name |
Human Readable Name | DRUGGABLE GENOME |
Interpro Type | Domain |
Interpro Short Name | PDEase_catalytic_dom |
DRUGGABLE GENOME |
PA33126 | PharmGKB ID |
PDE3 | TTD Gene Abbreviation |
T33754 | TTD Target ID |
ENSG00000172572 | Gene Symbol |
PDE3A | Ensembl Id |
DRUGGABLE GENOME |
PDE3A | GENE_SYMBOL |
cGMP-inhibited 3',5'-cyclic phosphodiesterase A | UNIPROT |
Cyclic GMP-inhibited phosphodiesterase A | UNIPROT |
PDE3A | TTD Gene Abbreviation |
T88975 | TTD Target ID |
cGMP-inhibited 3',5'-cyclic phosphodiesterase A | Gene Name |
Q14432 | UniProt ID |
ENZYME |