PDE3B Gene Record

  • PDE3B 5140 Druggable Genome

    Alternate Names:

    5140
    PHOSPHODIESTERASE 3B
    PDE3B
    HcGIP1
    cGIPDE1
    602047
    8779
    ENSG00000152270
    OTTHUMG00000165898
    Q13370
    CGMP-INHIBITED 3',5'-CYCLIC PHOSPHODIESTERASE B
    PDE3B_HUMAN
    ENSG00000261923
    CGMP-INHIBITED 3',5'-CYCLIC PHOSPHODIESTERASE B (EC 3.1.4.17) (CYCLIC GMP INHIBITED PHOSPHODIESTERASE B) (CGI-PDE B) (CGIPDE1) (CGIP1). [SOURCE:UNIPROT/SWISSPROT;ACC:Q13370]
    CGI-PDE B
    CGIP1
    Cyclic GMP-inhibited phosphodiesterase B
    T21357

    Gene Info:

    Target Class Enzymes
    Target Subclass EC:3.1.4.17
    Uniprot Evidence 1: Evidence at protein level
    Interpro Name 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain
    Uniprot Status Swiss-Prot
    Interpro Acc IPR002073
    Human Readable Name DRUGGABLE GENOME
    Interpro Type Domain
    Interpro Short Name PDEase_catalytic_dom
    Gene Biotype PROTEIN_CODING
    (3 More Sources)

    Gene Categories: Category Details

    DRUGGABLE GENOME

    Publications:

  • ANAGRELIDE HYDROCHLORIDE   PDE3B

    Interaction Score: 4.42

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Phosphodiesterase 3 inhibitor

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • THEOPHYLLINE SODIUM GLYCINATE   PDE3B

    Interaction Score: 0.88

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Phosphodiesterase 3 inhibitor

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • OXTRIPHYLLINE   PDE3B

    Interaction Score: 0.88

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Phosphodiesterase 3 inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • AMINOPHYLLINE   PDE3B

    Interaction Score: 0.88

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Phosphodiesterase 3 inhibitor

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • THEOPHYLLINE   PDE3B

    Interaction Score: 0.37

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Phosphodiesterase 3 inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • PENTOXIFYLLINE   PDE3B

    Interaction Score: 0.26

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction 3',5'-cyclic phosphodiesterase inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • DIPYRIDAMOLE   PDE3B

    Interaction Score: 0.17

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction 3',5'-cyclic phosphodiesterase inhibitor

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • Ensembl: ENSG00000152270

    • Version: 101_38

    Alternate Names:
    PDE3B Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • HopkinsGroom: Q13370

    • Version: 11-September-2012

    Alternate Names:
    PDE3B_HUMAN Uniprot Id
    ENSG00000261923 Ensembl Gene Id
    Q13370 Uniprot Accession

    Gene Info:
    Uniprot Evidence 1: Evidence at protein level
    Interpro Name 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain
    Uniprot Status Swiss-Prot

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • TdgClinicalTrial: Q13370

    • Version: January-2014

    Alternate Names:
    PDE3B Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:3.1.4.17

    Publications:

  • RussLampel: ENSG00000152270

    • Version: 26-July-2011

    Alternate Names:
    PDE3B Display Id
    CGMP-INHIBITED 3',5'-CYCLIC PHOSPHODIESTERASE B (EC 3.1.4.17) (CYCLIC GMP INHIBITED PHOSPHODIESTERASE B) (CGI-PDE B) (CGIPDE1) (CGIP1). [SOURCE:UNIPROT/SWISSPROT;ACC:Q13370] Description
    ENSG00000152270 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HingoraniCasas: ENSG00000152270

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000152270 Gene Symbol
    PDE3B Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • ChemblInteractions: PDE3B

    • Version: chembl_23

    Alternate Names:
    PDE3B GENE_SYMBOL
    cGMP-inhibited 3',5'-cyclic phosphodiesterase B UNIPROT
    CGIPDE1 UNIPROT

    Gene Info:

    Publications:

  • TTD: Phosphodiesterase 3B

    • Version: 2020.06.01

    Alternate Names:
    PDE3B TTD Gene Abbreviation
    T21357 TTD Target ID

    Gene Info:

    Publications: