PDE8A Gene Record

  • PDE8A 5151 Druggable Genome

    Alternate Names:

    5151
    PHOSPHODIESTERASE 8A
    PDE8A
    HsT19550
    602972
    8793
    ENSG00000073417
    OTTHUMG00000148670
    O60658
    HIGH AFFINITY CAMP-SPECIFIC AND IBMX-INSENSITIVE 3',5'-CYCLIC PHOSPHODIESTERASE 8A
    PDE8A_HUMAN
    HIGH-AFFINITY CAMP-SPECIFIC AND IBMX-INSENSITIVE 3',5'-CYCLIC PHOSPHODIESTERASE 8A (EC 3.1.4.17). [SOURCE:UNIPROT/SWISSPROT;ACC:O60658]

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Interpro Short Name PDEase_catalytic_dom
    Uniprot Status Swiss-Prot
    Interpro Acc IPR002073
    Interpro Name 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain
    Uniprot Evidence 1: Evidence at protein level
    Interpro Type Domain
    Gene Biotype PROTEIN_CODING
    (1 More Sources)

    Gene Categories: Category Details

    DRUGGABLE GENOME

    Publications:

  • FLAVOXATE HYDROCHLORIDE   PDE8A

    Interaction Score: 2.58

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Phosphodiesterase 8 inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • PENTOXIFYLLINE   PDE8A

    Interaction Score: 0.61

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction 3',5'-cyclic phosphodiesterase inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • DIPYRIDAMOLE   PDE8A

    Interaction Score: 0.4

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction 3',5'-cyclic phosphodiesterase inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • Ensembl: ENSG00000073417

    • Version: 101_38

    Alternate Names:
    PDE8A Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • HopkinsGroom: O60658

    • Version: 11-September-2012

    Alternate Names:
    PDE8A_HUMAN Uniprot Id
    PDE8A Uniprot Gene Name
    ENSG00000073417 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME
    Interpro Short Name PDEase_catalytic_dom
    Interpro Acc IPR002073

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • RussLampel: ENSG00000073417

    • Version: 26-July-2011

    Alternate Names:
    PDE8A Display Id
    HIGH-AFFINITY CAMP-SPECIFIC AND IBMX-INSENSITIVE 3',5'-CYCLIC PHOSPHODIESTERASE 8A (EC 3.1.4.17). [SOURCE:UNIPROT/SWISSPROT;ACC:O60658] Description
    ENSG00000073417 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HingoraniCasas: ENSG00000073417

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000073417 Gene Symbol
    PDE8A Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • ChemblInteractions: PDE8A

    • Version: chembl_23

    Alternate Names:
    PDE8A GENE_SYMBOL
    High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A UNIPROT

    Gene Info:

    Publications: