5241 |
PROGESTERONE RECEPTOR |
PGR |
NR3C3 |
PR |
607311 |
8910 |
ENSG00000082175 |
OTTHUMG00000167531 |
Nuclear receptor subfamily 3 group C member 3 |
P06401 |
PRGR_HUMAN |
PROGESTERONE RECEPTOR (PR). [SOURCE:UNIPROT/SWISSPROT;ACC:P06401] |
PA266 |
T22939 |
Target Class | Receptors |
Target Subclass | Nuclear receptor |
Human Readable Name | NUCLEAR HORMONE RECEPTOR |
Initial Gene Query | NR3C3 |
Counted Citations from 1950-2000 | 9831 |
Interpro Name | Nuclear hormone receptor, ligand-binding, core |
Interpro Acc | IPR000536 |
Interpro Type | Domain |
Uniprot Evidence | 1: Evidence at protein level |
Interpro Short Name | Nucl_hrmn_rcpt_lig-bd_core |
Human Readable Name | DRUGGABLE GENOME |
Uniprot Status | Swiss-Prot |
Target Main Class | Receptors |
Gene Biotype | PROTEIN_CODING |
NUCLEAR HORMONE RECEPTOR |
DRUGGABLE GENOME |
modulator |
Trial Name | Ulipristal |
Novel drug target | Established target |
Mechanism of Interaction | Progesterone receptor modulator |
agonist (activating) |
Mechanism of Interaction | Progesterone receptor agonist |
Direct Interaction | yes |
Trial Name | - |
agonist (activating) |
binder |
modulator |
Direct Interaction | yes |
Mechanism of Interaction | Progesterone receptor agonist |
Trial Name | SOH-075,NorLevo |
antagonist (inhibitory) |
modulator |
Mechanism of Interaction | Progesterone receptor modulator |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Progesterone receptor agonist |
Direct Interaction | yes |
Novel drug target | Established target |
agonist (activating) |
Trial Name | - |
Novel drug target | Established target |
Direct Interaction | yes |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Progesterone receptor agonist |
Trial Name | drospirenone plus estradiol,Angeliq |
agonist (activating) |
Trial Name | norelgestromin/ethinyl estradiol,Ortho Evra |
Novel drug target | Established target |
Mechanism of Interaction | Progesterone receptor agonist |
antagonist (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Progesterone receptor antagonist |
agonist (activating) |
Trial Name | etonogestrel implant,Implanon |
Novel drug target | Established target |
Trial Name | etonogestrel/ethinyl estradiol vaginal ring,Nuvaring |
n/a |
Trial Name | - |
Novel drug target | Established target |
agonist (activating) |
Mechanism of Interaction | Progesterone receptor agonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Progesterone receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Progesterone receptor antagonist |
Direct Interaction | yes |
agonist (activating) |
Trial Name | estradiol valerate + dienogest,Natazia, Qlaira |
Novel drug target | Established target |
n/a |
Trial Name | oral contraceptive,Pill-Plus |
Novel drug target | Established target |
activator (activating) |
binder |
Trial Name | contraceptive patch, ethinylestradiol + gestodene,FC Patch Fidencia |
Novel drug target | Established target |
modulator |
Direct Interaction | yes |
Mechanism of Interaction | Progesterone receptor modulator |
modulator |
Direct Interaction | yes |
Mechanism of Interaction | Progesterone receptor modulator |
agonist (activating) |
binder |
Trial Name | - |
Novel drug target | Established target |
Mechanism of Interaction | Progesterone receptor agonist |
agonist (activating) |
Mechanism of Interaction | Progesterone receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Progesterone receptor agonist |
Direct Interaction | yes |
agonist (activating) |
antagonist (inhibitory) |
Mechanism of Interaction | Progesterone receptor antagonist |
Direct Interaction | yes |
Trial Name | Mifepristone, RU486 |
agonist (activating) |
Mechanism of Interaction | Progesterone receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Progesterone receptor agonist |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Progesterone receptor agonist |
agonist (activating) |
Mechanism of Interaction | Progesterone receptor agonist |
Direct Interaction | yes |
n/a |
n/a |
agonist (activating) |
Trial Name | BHR-100 |
Novel drug target | Established target |
Trial Name | conjugated estrogens/medroxyprogesterone acetate,Prempro, Premphase |
n/a |
PGR | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
PRGR_HUMAN | Uniprot Id |
ENSG00000082175 | Ensembl Gene Id |
P06401 | Uniprot Accession |
Target Subclass | Nuclear receptor |
Target Main Class | Receptors |
5241 | Entrez Gene ID |
Initial Gene Query | NR3C3 |
Counted Citations from 1950-2000 | 9831 |
NUCLEAR HORMONE RECEPTOR |
P06401 | Uniprot Accession |
PRGR_HUMAN | Uniprot Id |
5241 | Entrez Gene Id |
Interpro Name | Nuclear hormone receptor, ligand-binding, core |
Interpro Acc | IPR000536 |
Interpro Type | Domain |
NUCLEAR HORMONE RECEPTOR, DRUGGABLE GENOME |
PGR | Gene Symbol |
Target Class | Receptors |
Target Subclass | Nuclear receptor |
ENSG00000082175 | Ensembl Gene Id |
PGR | Display Id |
PROGESTERONE RECEPTOR (PR). [SOURCE:UNIPROT/SWISSPROT;ACC:P06401] | Description |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
NR3C3 | GENE_SYMBOL |
PGR | GENE_SYMBOL |
Progesterone receptor | UNIPROT |
ENSG00000082175 | Gene Symbol |
PGR | Ensembl Id |
DRUGGABLE GENOME |
PA266 | PharmGKB ID |
NR3C3 | GO Gene Synonym |
NUCLEAR HORMONE RECEPTOR |
5241 | Gene ID |
NR3C3 | dGene Synonym |
PR | dGene Synonym |
NUCLEAR HORMONE RECEPTOR |
PGR | TTD Gene Abbreviation |
T22939 | TTD Target ID |