DGIdb - PIK3CD Gene Record

PIK3CD 5293 Druggable GenomeClinically Actionable

Alternate Names:

5293
PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA
PIK3CD
APDS
IMD14
P110DELTA
PI3K
p110D
602839
8977
ENSG00000171608
OTTHUMG00000001450
O00329
PK3CD_HUMAN
PtdIns-3-kinase subunit p110-delta
PtdIns-3-kinase subunit delta
PI3Kdelta
PI3K-delta
PI3-kinase subunit delta
Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT, DELTA ISOFORM (EC 2.7.1.153) (PI3-KINASE P110 SUBUNIT DELTA) (PTDINS- 3-KINASE P110) (PI3K) (P110DELTA). [SOURCE:UNIPROT/SWISSPROT;ACC:O00329]
PI3KCD
PI3-kinase delta
T67849
IMD14A
IMD14B
ROCHIS

Gene Info:

Human Readable Name	PHOSPHATIDYLINOSITOL 3 KINASE
Target Class	Enzymes
Target Subclass	EC:2.7.1.153
Human Readable Name	DRUGGABLE GENOME
Interpro Name	Phosphatidylinositol 3-/4-kinase, catalytic domain
Interpro Short Name	PI3/4_kinase_cat_dom
Interpro Type	Domain
Uniprot Evidence	1: Evidence at protein level
Uniprot Status	Swiss-Prot
Interpro Acc	IPR000403
Gene Biotype	PROTEIN_CODING

(11 More Sources)

Gene Categories: Category Details

KINASE
DRUGGABLE GENOME
PHOSPHATIDYLINOSITOL 3 KINASE
CLINICALLY ACTIONABLE

Publications:

Boyle DL et al., 2014, Novel phosphoinositide 3-kinase δ,γ inhibitor: potent anti-inflammatory effects and joint protection in models of rheumatoid arthritis., J Pharmacol Exp Ther
Vangapandu HV et al., 2017, Duvelisib: a phosphoinositide-3 kinase δ/γ inhibitor for chronic lymphocytic leukemia., Expert Opin Investig Drugs
Lampson BL et al., 2017, PI3Kδ-selective and PI3Kα/δ-combinatorial inhibitors in clinical development for B-cell non-Hodgkin lymphoma., Expert Opin Investig Drugs
Palanki et al., 2007, Discovery of 3,3'-(2,4-diaminopteridine-6,7-diyl)diphenol as an isozyme-selective inhibitor of PI3K for the treatment of ischemia reperfusion injury associated with myocardial infarction., J. Med. Chem.

ME-401 PIK3CD

Interaction Score: 2.63

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

PMIDs:
None found

Sources:
ChemblInteractions TTD
DUVELISIB PIK3CD

Interaction Score: 2.19

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

Direct Interaction yes

PMIDs:
24244039 28388280 28945111

Sources:
ChemblInteractions TTD
GS-9901 PIK3CD

Interaction Score: 1.32

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD
AMG-319 PIK3CD

Interaction Score: 1.32

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
UMBRALISIB TOSYLATE PIK3CD

Interaction Score: 1.32

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD
INCB-40093 PIK3CD

Interaction Score: 1.32

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
GSK-2269557 PIK3CD

Interaction Score: 1.32

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

PMIDs:
None found

Sources:
ChemblInteractions
IDELALISIB PIK3CD

Interaction Score: 1.32

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Trial Name CAL-101

Novel drug target Novel Target

Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

PMIDs:
None found

Sources:
MyCancerGenome TdgClinicalTrial ChemblInteractions TTD
ACALISIB PIK3CD

Interaction Score: 0.88

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD
RP-6530 PIK3CD

Interaction Score: 0.66

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
CAL-263 PIK3CD

Interaction Score: 0.66

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
TG100-115 PIK3CD

Interaction Score: 0.66

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

PMIDs:
17685602

Sources:
ChemblInteractions
AZD-8186 PIK3CD

Interaction Score: 0.26

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

PMIDs:
None found

Sources:
ChemblInteractions
SONOLISIB PIK3CD

Interaction Score: 0.26

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
MyCancerGenome ChemblInteractions MyCancerGenomeClinicalTrial
COPANLISIB PIK3CD

Interaction Score: 0.23

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction PI3-kinase class I inhibitor

PMIDs:
None found

Sources:
MyCancerGenome ChemblInteractions MyCancerGenomeClinicalTrial
PA-799 PIK3CD

Interaction Score: 0.22

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD
BUPARLISIB PIK3CD

Interaction Score: 0.22

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
MyCancerGenome ClearityFoundationClinicalTrial ChemblInteractions TTD
OMIPALISIB PIK3CD

Interaction Score: 0.21

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ClearityFoundationClinicalTrial ChemblInteractions MyCancerGenomeClinicalTrial
PILARALISIB PIK3CD

Interaction Score: 0.2

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
MyCancerGenome ClearityFoundationClinicalTrial ChemblInteractions
WX-037 PIK3CD

Interaction Score: 0.16

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
GSK-1059615 PIK3CD

Interaction Score: 0.16

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
ZSTK-474 PIK3CD

Interaction Score: 0.16

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
RECILISIB PIK3CD

Interaction Score: 0.16

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
PF-04691502 PIK3CD

Interaction Score: 0.15

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
MyCancerGenome ChemblInteractions
BGT-226 PIK3CD

Interaction Score: 0.15

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
RG-7666 PIK3CD

Interaction Score: 0.15

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
RIGOSERTIB PIK3CD

Interaction Score: 0.15

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name ON 01910.Na,Estybon

Novel drug target Novel Target

PMIDs:
None found

Sources:
TdgClinicalTrial
SF-1126 PIK3CD

Interaction Score: 0.15

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
VOXTALISIB PIK3CD

Interaction Score: 0.15

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction PI3-kinase class I inhibitor

PMIDs:
None found

Sources:
MyCancerGenome ChemblInteractions
PWT-33587 PIK3CD

Interaction Score: 0.15

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction PI3-kinase class I inhibitor

PMIDs:
None found

Sources:
ChemblInteractions
GEDATOLISIB PIK3CD

Interaction Score: 0.14

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
MyCancerGenome ChemblInteractions MyCancerGenomeClinicalTrial
SAMOTOLISIB PIK3CD

Interaction Score: 0.13

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction PI3-kinase class I inhibitor

PMIDs:
None found

Sources:
ChemblInteractions
APITOLISIB PIK3CD

Interaction Score: 0.13

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
MyCancerGenome ChemblInteractions
PUQUITINIB PIK3CD

Interaction Score: 0.12

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
TASELISIB PIK3CD

Interaction Score: 0.12

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
VS-5584 PIK3CD

Interaction Score: 0.11

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
PANULISIB PIK3CD

Interaction Score: 0.11

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
DS-7423 PIK3CD

Interaction Score: 0.11

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
AZD-6482 PIK3CD

Interaction Score: 0.11

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction PI3-kinase class I inhibitor

PMIDs:
None found

Sources:
ChemblInteractions
DACTOLISIB PIK3CD

Interaction Score: 0.09

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction PI3-kinase class I inhibitor

PMIDs:
None found

Sources:
MyCancerGenome ChemblInteractions MyCancerGenomeClinicalTrial
PICTILISIB PIK3CD

Interaction Score: 0.09

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction PI3-kinase class I inhibitor

PMIDs:
None found

Sources:
MyCancerGenome ChemblInteractions
GSK-2636771 PIK3CD

Interaction Score: 0.08

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
None found

Sources:
MyCancerGenome
ALPELISIB PIK3CD

Interaction Score: 0.08

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
None found

Sources:
MyCancerGenome MyCancerGenomeClinicalTrial
FIMEPINOSTAT PIK3CD

Interaction Score: 0.07

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
PI-103 PIK3CD

Interaction Score: 0.07

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
None found

Sources:
MyCancerGenome
INFIGRATINIB PIK3CD

Interaction Score: 0.06

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
None found

Sources:
MyCancerGenome
QUERCETIN PIK3CD

Interaction Score: 0.02

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
None found

Sources:
MyCancerGenome

Ensembl: ENSG00000171608
- Version: 101_38
Alternate Names:

PIK3CD Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:

RussLampel: ENSG00000171608

Version: 26-July-2011

Alternate Names:

PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT, DELTA ISOFORM (EC 2.7.1.153) (PI3-KINASE P110 SUBUNIT DELTA) (PTDINS- 3-KINASE P110) (PI3K) (P110DELTA). [SOURCE:UNIPROT/SWISSPROT;ACC:O00329] Description

PIK3CD Display Id

ENSG00000171608 Ensembl Gene Id

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:

TdgClinicalTrial: O00329
- Version: January-2014
Alternate Names:

PIK3CD Gene Symbol

Gene Info:

Target Class Enzymes

Target Subclass EC:2.7.1.153

Publications:
HopkinsGroom: O00329
- Version: 11-September-2012
Alternate Names:

PK3CD_HUMAN Uniprot Id

ENSG00000171608 Ensembl Gene Id

PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM Uniprot Protein Name

Gene Info:

Interpro Name Phosphatidylinositol 3-/4-kinase, catalytic domain

Interpro Short Name PI3/4_kinase_cat_dom

Interpro Type Domain

Gene Categories:

DRUGGABLE GENOME, PHOSPHATIDYLINOSITOL 3 KINASE

Publications:

ChemblInteractions: PIK3CD

Version: chembl_23

Alternate Names:

PIK3CD GENE_SYMBOL

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform UNIPROT

Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta UNIPROT

Gene Info:

Publications:

HingoraniCasas: ENSG00000171608
- Version: 31-May-2017
Alternate Names:

ENSG00000171608 Gene Symbol

PIK3CD Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
MyCancerGenome: PIK3CD
- Version: 20-Jun-2017
Alternate Names:

5293 Entrez Gene Id

PIK3CD MyCancerGenome Gene Symbol

PI3K MyCancerGenome Reported Gene Name

Gene Info:

Publications:
Tempus: PIK3CD
- Version: 11-November-2018
Alternate Names:

PIK3CD Gene Symbol

Gene Info:

Gene Categories:

CLINICALLY ACTIONABLE

Publications:
dGene: PIK3CD
- Version: 27-Jun-2013
Alternate Names:

5293 Gene ID

P110DELTA dGene Synonym

PI3K dGene Synonym

Gene Info:

Gene Categories:

KINASE, PHOSPHATIDYLINOSITOL 3 KINASE

Publications:
TTD: PI3-kinase delta
- Version: 2020.06.01
Alternate Names:

PIK3CD TTD Gene Abbreviation

T67849 TTD Target ID

Gene Info:

Publications:
Pharos: PIK3CD
- Version: 01-February-2022
Alternate Names:

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Gene Name

O00329 UniProt ID

Gene Info:

Gene Categories:

KINASE

Publications:
MyCancerGenomeClinicalTrial: PIK3CD
- Version: 30-February-2014
Alternate Names:

Gene Info:

Publications:
ClearityFoundationClinicalTrial: PI3KCD
- Version: 15-June-2013
Alternate Names:

Gene Info:

Publications:
MskImpact: PIK3CD
- Version: May-2015
Alternate Names:

Gene Info:

Gene Categories:

CLINICALLY ACTIONABLE

Publications:
GO: PIK3CD
- Version: 01-February-2022
Alternate Names:

Gene Info:

Gene Categories:

KINASE

Publications:

Direct Interaction	yes
Mechanism of Interaction	PI3-kinase p110-delta subunit inhibitor

Trial Name	CAL-101
Novel drug target	Novel Target
Mechanism of Interaction	PI3-kinase p110-delta subunit inhibitor

Mechanism of Interaction	PI3-kinase class I inhibitor
Direct Interaction	yes

PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT, DELTA ISOFORM (EC 2.7.1.153) (PI3-KINASE P110 SUBUNIT DELTA) (PTDINS- 3-KINASE P110) (PI3K) (P110DELTA). [SOURCE:UNIPROT/SWISSPROT;ACC:O00329]	Description
PIK3CD	Display Id
ENSG00000171608	Ensembl Gene Id

PK3CD_HUMAN	Uniprot Id
ENSG00000171608	Ensembl Gene Id
PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM	Uniprot Protein Name

PIK3CD	GENE_SYMBOL
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	UNIPROT
Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta	UNIPROT

5293	Entrez Gene Id
PIK3CD	MyCancerGenome Gene Symbol
PI3K	MyCancerGenome Reported Gene Name

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Gene Name
O00329	UniProt ID

PIK3CD Gene Record

PIK3CD 5293 Druggable GenomeClinically Actionable

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Direct Interaction yes Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

PMIDs: None found

Sources: ChemblInteractions TTD

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor Direct Interaction yes

PMIDs: 24244039 28388280 28945111

Sources: ChemblInteractions TTD

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: TTD

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions TTD

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Direct Interaction yes Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

PMIDs: None found

Sources: ChemblInteractions

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Trial Name CAL-101 Novel drug target Novel Target Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

PMIDs: None found

Sources: MyCancerGenome TdgClinicalTrial ChemblInteractions TTD

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions TTD

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Direct Interaction yes Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

PMIDs: 17685602

Sources: ChemblInteractions

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Direct Interaction yes Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

PMIDs: None found

Sources: ChemblInteractions

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction PI3-kinase class I inhibitor Direct Interaction yes

PMIDs: None found

Sources: MyCancerGenome ChemblInteractions MyCancerGenomeClinicalTrial

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Direct Interaction yes Mechanism of Interaction PI3-kinase class I inhibitor

PMIDs: None found

Sources: MyCancerGenome ChemblInteractions MyCancerGenomeClinicalTrial

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction PI3-kinase class I inhibitor Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions TTD

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction PI3-kinase class I inhibitor Direct Interaction yes

PMIDs: None found

Sources: MyCancerGenome ClearityFoundationClinicalTrial ChemblInteractions TTD

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction PI3-kinase class I inhibitor Direct Interaction yes

PMIDs: None found

Sources: ClearityFoundationClinicalTrial ChemblInteractions MyCancerGenomeClinicalTrial

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction PI3-kinase class I inhibitor Direct Interaction yes

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

PMIDs:
None found

Sources:
ChemblInteractions TTD

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

Direct Interaction yes

PMIDs:
24244039 28388280 28945111

Sources:
ChemblInteractions TTD

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
TTD

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Trial Name CAL-101

Novel drug target Novel Target

Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

PMIDs:
None found

Sources:
MyCancerGenome TdgClinicalTrial ChemblInteractions TTD

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

PMIDs:
17685602

Sources:
ChemblInteractions

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction PI3-kinase p110-delta subunit inhibitor

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
MyCancerGenome ChemblInteractions MyCancerGenomeClinicalTrial

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction PI3-kinase class I inhibitor

PMIDs:
None found

Sources:
MyCancerGenome ChemblInteractions MyCancerGenomeClinicalTrial

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
MyCancerGenome ClearityFoundationClinicalTrial ChemblInteractions TTD

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ClearityFoundationClinicalTrial ChemblInteractions MyCancerGenomeClinicalTrial

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
MyCancerGenome ClearityFoundationClinicalTrial ChemblInteractions

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction PI3-kinase class I inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

inhibitor (inhibitory)