PKM Gene Record

  • PKM 5315 Druggable Genome

    Alternate Names:

    5315
    PYRUVATE KINASE, MUSCLE
    PKM
    CTHBP
    HEL-S-30
    OIP3
    PK3
    PKM2
    TCB
    THBP1
    179050
    9021
    ENSG00000067225
    OTTHUMG00000172709
    P14618
    PYRUVATE KINASE M1/2
    Pyruvate kinase M2
    T65889
    p58
    PK2
    Pyruvate kinase PKM

    Gene Info:

    Target Class Enzymes
    Target Subclass EC:2.7.1.40
    Gene Biotype PROTEIN_CODING
    (3 More Sources)

    Gene Categories: Category Details

    KINASE
    DRUGGABLE GENOME
    ENZYME

    Publications:

  • CHEMBL585265   PKM

    Interaction Score: 1.82

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TT-232   PKM

    Interaction Score: 1.82

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Novel drug target Novel Target
    Trial Name TLN-232, CAP-232, TT-232

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • CHEMBL1091502   PKM

    Interaction Score: 1.82

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL1093369   PKM

    Interaction Score: 0.91

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • SULFADIAZINE, SILVER   PKM

    Interaction Score: 0.61

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL1214407   PKM

    Interaction Score: 0.45

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL261693   PKM

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL429335   PKM

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL1333049   PKM

    Interaction Score: 0.26

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CIS-RESVERATROL   PKM

    Interaction Score: 0.26

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL1303948   PKM

    Interaction Score: 0.26

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL473721   PKM

    Interaction Score: 0.23

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL125044   PKM

    Interaction Score: 0.2

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL595227   PKM

    Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TRANILAST   PKM

    Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL154580   PKM

    Interaction Score: 0.17

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL297784   PKM

    Interaction Score: 0.17

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL408850   PKM

    Interaction Score: 0.17

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • NITAZOXANIDE   PKM

    Interaction Score: 0.15

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • AMLEXANOX   PKM

    Interaction Score: 0.15

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ERBSTATIN   PKM

    Interaction Score: 0.13

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL584458   PKM

    Interaction Score: 0.13

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL599013   PKM

    Interaction Score: 0.13

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HYDRALAZINE   PKM

    Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PSEUDOEPHEDRINE   PKM

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • INDIRUBIN-3-MONOXIME   PKM

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL56731   PKM

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL576409   PKM

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • THIRAM   PKM

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • SANGUINARIUM   PKM

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • NICLOSAMIDE   PKM

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • 4-CHLOROMERCURIBENZOIC ACID   PKM

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • EBSELEN   PKM

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL35482   PKM

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Ensembl: ENSG00000067225

    • Version: 101_38

    Alternate Names:
    PKM Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • TdgClinicalTrial: P14618

    • Version: January-2014

    Alternate Names:
    PKM2 Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:2.7.1.40

    Publications:

  • HingoraniCasas: ENSG00000067225

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000067225 Gene Symbol
    PKM Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • GO: PKM

    • Version: 01-February-2022

    Alternate Names:
    OIP3 GO Gene Synonym
    PK2 GO Gene Synonym
    PK3 GO Gene Synonym

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

  • TTD: Pyruvate kinase M2

    • Version: 2020.06.01

    Alternate Names:
    PKM TTD Gene Abbreviation
    T65889 TTD Target ID

    Gene Info:

    Publications:

  • Pharos: PKM

    • Version: 01-February-2022

    Alternate Names:
    Pyruvate kinase PKM Gene Name
    P14618 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE, ENZYME

    Publications:

  • DTC: PKM

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications: