PLA2G5 Gene Record

  • PLA2G5 5322 Druggable Genome

    Alternate Names:

    5322
    PHOSPHOLIPASE A2 GROUP V
    PLA2G5
    FRFB
    GV-PLA2
    PLA2-10
    hVPLA(2)
    601192
    9038
    ENSG00000127472
    OTTHUMG00000002698
    Phosphatidylcholine 2-acylhydrolase 5
    Group V phospholipase A2
    Calcium-dependent phospholipase A2
    P39877
    CALCIUM-DEPENDENT PHOSPHOLIPASE A2 PRECURSOR (EC 3.1.1.4) (PHOSPHATIDYLCHOLINE 2-ACYLHYDROLASE) (PLA2-10) (GROUP V PHOSPHOLIPASE A2). [SOURCE:UNIPROT/SWISSPROT;ACC:P39877]
    PA2G5_HUMAN

    Gene Info:

    Target Class Enzymes
    Target Subclass EC:3.1.1.4
    Human Readable Name DRUGGABLE GENOME
    Human Readable Name PHOSPHOLIPASE
    Uniprot Evidence 1: Evidence at protein level
    Interpro Acc IPR001211
    Interpro Type Family
    Uniprot Status Swiss-Prot
    Interpro Name Phospholipase A2, eukaryotic
    Interpro Short Name PLipase_A2_euk
    Gene Biotype PROTEIN_CODING
    (4 More Sources)

    Gene Categories: Category Details

    PHOSPHOLIPASE
    DRUGGABLE GENOME
    ENZYME

    Publications:

  • VARESPLADIB METHYL   PLA2G5

    Interaction Score: 10.3

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Phospholipase A2 group V inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • VARESPLADIB   PLA2G5

    Interaction Score: 10.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name varespladib, A-002
    Novel drug target Novel Target
    Trial Name varespladib sodium, A-001

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • Ensembl: ENSG00000127472

    • Version: 101_38

    Alternate Names:
    PLA2G5 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • HopkinsGroom: P39877

    • Version: 11-September-2012

    Alternate Names:
    5322 Entrez Gene Id
    CALCIUM-DEPENDENT PHOSPHOLIPASE A2 Uniprot Protein Name
    PLA2G5 Uniprot Gene Name

    Gene Info:
    Human Readable Name PHOSPHOLIPASE
    Uniprot Evidence 1: Evidence at protein level
    Interpro Acc IPR001211

    Gene Categories:
    PHOSPHOLIPASE, DRUGGABLE GENOME

    Publications:

  • TdgClinicalTrial: P39877

    • Version: January-2014

    Alternate Names:
    PLA2G5 Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:3.1.1.4

    Publications:

  • RussLampel: ENSG00000127472

    • Version: 26-July-2011

    Alternate Names:
    PLA2G5 Display Id
    ENSG00000127472 Ensembl Gene Id
    CALCIUM-DEPENDENT PHOSPHOLIPASE A2 PRECURSOR (EC 3.1.1.4) (PHOSPHATIDYLCHOLINE 2-ACYLHYDROLASE) (PLA2-10) (GROUP V PHOSPHOLIPASE A2). [SOURCE:UNIPROT/SWISSPROT;ACC:P39877] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • ChemblInteractions: PLA2G5

    • Version: chembl_23

    Alternate Names:
    PLA2G5 GENE_SYMBOL
    Calcium-dependent phospholipase A2 UNIPROT
    Group V phospholipase A2 UNIPROT

    Gene Info:

    Publications:

  • HingoraniCasas: ENSG00000127472

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000127472 Gene Symbol
    PLA2G5 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HumanProteinAtlas: PLA2G5

    • Version: 19.3

    Alternate Names:
    ENSG00000127472 Ensembl Gene ID
    Phospholipase A2 group V Human Protein Atlas Gene Description
    P39877 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

  • Pharos: PLA2G5

    • Version: 01-February-2022

    Alternate Names:
    Calcium-dependent phospholipase A2 Gene Name
    P39877 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications: