5578 |
PROTEIN KINASE C ALPHA |
PRKCA |
AAG6 |
PKC-alpha |
PKCA |
PRKACA |
176960 |
9393 |
ENSG00000154229 |
OTTHUMG00000179533 |
P17252 |
PROTEIN KINASE C ALPHA TYPE |
KPCA_HUMAN |
PKC-A |
PROTEIN KINASE C, ALPHA TYPE (EC 2.7.1.37) (PKC-ALPHA) (PKC-A). [SOURCE:UNIPROT/SWISSPROT;ACC:P17252] |
PKC |
PA33759 |
T12808 |
PKCI+/- |
PKCalpha |
Initial Gene Query | PKC alpha |
Counted Citations from 1950-2000 | 2549 |
Human Readable Name | DRUGGABLE GENOME |
Interpro Type | Domain |
Interpro Short Name | Ser/Thr_dual-sp_kinase_dom |
Interpro Acc | IPR002290 |
Human Readable Name | KINASE |
Uniprot Evidence | 1: Evidence at protein level |
Uniprot Status | Swiss-Prot |
Interpro Name | Serine/threonine- / dual-specificity protein kinase, catalytic domain |
Target Class | Enzymes |
Target Subclass | EC:2.7.11.13 |
Gene Biotype | PROTEIN_CODING |
KINASE |
SERINE THREONINE KINASE |
DRUGGABLE GENOME |
CLINICALLY ACTIONABLE |
n/a |
Trial Name | Bryostatin |
Novel drug target | Established target |
inhibitor (inhibitory) |
antagonist (inhibitory) |
inhibitor (inhibitory) |
Mechanism of Interaction | Protein kinase C (PKC) inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Protein kinase C (PKC) inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Protein kinase C (PKC) inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Protein kinase C (PKC) inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Protein kinase C (PKC) inhibitor |
inhibitor (inhibitory) |
PRKCA | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
5578 | Entrez Gene ID |
Initial Gene Query | PKC alpha |
Counted Citations from 1950-2000 | 2549 |
KINASE |
PRKCA | Display Id |
PROTEIN KINASE C, ALPHA TYPE (EC 2.7.1.37) (PKC-ALPHA) (PKC-A). [SOURCE:UNIPROT/SWISSPROT;ACC:P17252] | Description |
ENSG00000154229 | Ensembl Gene Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
PRKCA | Gene Symbol |
Target Class | Enzymes |
Target Subclass | EC:2.7.11.13 |
ENSG00000154229 | Ensembl Gene Id |
5578 | Entrez Gene Id |
PRKCA | Uniprot Gene Name |
Human Readable Name | DRUGGABLE GENOME |
Interpro Type | Domain |
Interpro Short Name | Ser/Thr_dual-sp_kinase_dom |
KINASE, DRUGGABLE GENOME |
PA33759 | PharmGKB ID |
PKCA | Gene Symbol |
5578 | Entrez Gene Id |
PRKCA | MyCancerGenome Gene Symbol |
PKC-alpha | MyCancerGenome Reported Gene Name |
ENSG00000154229 | Gene Symbol |
PRKCA | Ensembl Id |
DRUGGABLE GENOME |
PKCA | GENE_SYMBOL |
PRKACA | GENE_SYMBOL |
PRKCA | GENE_SYMBOL |
PKCA | GO Gene Synonym |
PRKACA | GO Gene Synonym |
SERINE THREONINE KINASE |
5578 | Gene ID |
AAG6 | dGene Synonym |
PKC-alpha | dGene Synonym |
KINASE, SERINE THREONINE KINASE |
PRKCA | TTD Gene Abbreviation |
T12808 | TTD Target ID |
Protein kinase C alpha type | Gene Name |
P17252 | UniProt ID |
KINASE |
CLINICALLY ACTIONABLE |