PRKCQ Gene Record

  • PRKCQ 5588 Druggable Genome

    Alternate Names:

    5588
    PROTEIN KINASE C THETA
    PRKCQ
    PRKCT
    nPKC-theta
    600448
    9410
    ENSG00000065675
    OTTHUMG00000017623
    Protein kinase C theta type
    Q04759
    KPCT_HUMAN
    PROTEIN KINASE C, THETA TYPE (EC 2.7.1.-) (NPKC-THETA). [SOURCE:UNIPROT/SWISSPROT;ACC:Q04759]
    PKC
    T23995

    Gene Info:

    Target Class Enzymes
    Target Subclass EC:2.7.11.13
    Human Readable Name DRUGGABLE GENOME
    Uniprot Evidence 1: Evidence at protein level
    Uniprot Status Swiss-Prot
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Interpro Acc IPR002290
    Human Readable Name KINASE
    Interpro Type Domain
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Gene Biotype PROTEIN_CODING
    (8 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    DRUGGABLE GENOME
    TRANSCRIPTION FACTOR

    Publications:

  • BRYOSTATIN   PRKCQ

    Interaction Score: 0.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name Bryostatin
    Novel drug target Established target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • GSK-690693   PRKCQ

    Interaction Score: 0.21

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Protein kinase C (PKC) inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • CEP-2563   PRKCQ

    Interaction Score: 0.21

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Protein kinase C (PKC) inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • UCN-01   PRKCQ

    Interaction Score: 0.18

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Protein kinase C (PKC) inhibitor

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • MIDOSTAURIN   PRKCQ

    Interaction Score: 0.15

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Protein kinase C (PKC) inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • SOTRASTAURIN   PRKCQ

    Interaction Score: 0.13

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Protein kinase C (PKC) inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    DTC ChemblInteractions

  • ADAVOSERTIB   PRKCQ

    Interaction Score: 0.13

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • FASUDIL   PRKCQ

    Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL546797   PRKCQ

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL1997335   PRKCQ

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL379975   PRKCQ

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ENTRECTINIB   PRKCQ

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL225519   PRKCQ

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   PRKCQ

    Interaction Score: 0.05

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • TAE-684   PRKCQ

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PF-00562271   PRKCQ

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CENISERTIB   PRKCQ

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Ensembl: ENSG00000065675

    • Version: 101_38

    Alternate Names:
    PRKCQ Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • RussLampel: ENSG00000065675

    • Version: 26-July-2011

    Alternate Names:
    PROTEIN KINASE C, THETA TYPE (EC 2.7.1.-) (NPKC-THETA). [SOURCE:UNIPROT/SWISSPROT;ACC:Q04759] Description
    PRKCQ Display Id
    ENSG00000065675 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HopkinsGroom: Q04759

    • Version: 11-September-2012

    Alternate Names:
    ENSG00000065675 Ensembl Gene Id
    5588 Entrez Gene Id
    KPCT_HUMAN Uniprot Id

    Gene Info:
    Uniprot Evidence 1: Evidence at protein level
    Uniprot Status Swiss-Prot
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

  • TdgClinicalTrial: Q04759

    • Version: January-2014

    Alternate Names:
    PRKCQ Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:2.7.11.13

    Publications:

  • MyCancerGenome: PRKCQ

    • Version: 20-Jun-2017

    Alternate Names:
    5588 Entrez Gene Id
    PRKCQ MyCancerGenome Gene Symbol
    PKC MyCancerGenome Reported Gene Name

    Gene Info:

    Publications:

  • HingoraniCasas: ENSG00000065675

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000065675 Gene Symbol
    PRKCQ Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • ChemblInteractions: PRKCT

    • Version: chembl_23

    Alternate Names:
    PRKCT GENE_SYMBOL
    PRKCQ GENE_SYMBOL
    Protein kinase C theta type UNIPROT

    Gene Info:

    Publications:

  • GO: PRKCQ

    • Version: 01-February-2022

    Alternate Names:
    PRKCT GO Gene Synonym

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE

    Publications:

  • dGene: PRKCQ

    • Version: 27-Jun-2013

    Alternate Names:
    5588 Gene ID
    PRKCT dGene Synonym
    nPKC-theta dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

  • TTD: Protein kinase C theta

    • Version: 2020.06.01

    Alternate Names:
    PRKCQ TTD Gene Abbreviation
    T23995 TTD Target ID

    Gene Info:

    Publications:

  • Pharos: PRKCQ

    • Version: 01-February-2022

    Alternate Names:
    Protein kinase C theta type Gene Name
    Q04759 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE, TRANSCRIPTION FACTOR

    Publications:

  • DTC: PRKCQ

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications: