PRKCZ Gene Record

  • PRKCZ 5590 Druggable Genome

    Alternate Names:

    5590
    PROTEIN KINASE C ZETA
    PRKCZ
    PKC-ZETA
    PKC2
    176982
    9412
    ENSG00000067606
    OTTHUMG00000001238
    PROTEIN KINASE C, ZETA TYPE (EC 2.7.1.37) (NPKC-ZETA). [SOURCE:UNIPROT/SWISSPROT;ACC:Q05513]
    PKC
    Protein kinase C zeta type
    nPKC-zeta
    Q05513
    KPCZ_HUMAN
    T59190

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Initial Gene Query PKC zeta
    Counted Citations from 1950-2000 789
    Interpro Type Domain
    Interpro Acc IPR002290
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Uniprot Evidence 1: Evidence at protein level
    Uniprot Status Swiss-Prot
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Human Readable Name KINASE
    Target Class Enzymes
    Target Subclass EC:2.7.11.13
    Gene Biotype PROTEIN_CODING
    (9 More Sources)

    Gene Categories: Category Details

    TRANSPORTER
    KINASE
    SERINE THREONINE KINASE
    DRUGGABLE GENOME

    Publications:

  • GSK-690693   PRKCZ

    Interaction Score: 0.33

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Protein kinase C (PKC) inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • CEP-2563   PRKCZ

    Interaction Score: 0.33

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Protein kinase C (PKC) inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • UCN-01   PRKCZ

    Interaction Score: 0.28

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Protein kinase C (PKC) inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • MIDOSTAURIN   PRKCZ

    Interaction Score: 0.22

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Protein kinase C (PKC) inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • LAUROGUADINE   PRKCZ

    Interaction Score: 0.2

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • SOTRASTAURIN   PRKCZ

    Interaction Score: 0.2

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Protein kinase C (PKC) inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    DTC ChemblInteractions

  • GSK-269962A   PRKCZ

    Interaction Score: 0.13

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL225519   PRKCZ

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TOZASERTIB   PRKCZ

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   PRKCZ

    Interaction Score: 0.07

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • CENISERTIB   PRKCZ

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Ensembl: ENSG00000067606

    • Version: 101_38

    Alternate Names:
    PRKCZ Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • RussLampel: ENSG00000067606

    • Version: 26-July-2011

    Alternate Names:
    PROTEIN KINASE C, ZETA TYPE (EC 2.7.1.37) (NPKC-ZETA). [SOURCE:UNIPROT/SWISSPROT;ACC:Q05513] Description
    PRKCZ Display Id
    ENSG00000067606 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • TdgClinicalTrial: Q05513

    • Version: January-2014

    Alternate Names:
    PRKCZ Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:2.7.11.13

    Publications:

  • BaderLabGenes: PRKCZ

    • Version: February-2014

    Alternate Names:
    5590 Entrez Gene ID

    Gene Info:
    Initial Gene Query PKC zeta
    Counted Citations from 1950-2000 789

    Gene Categories:
    KINASE

    Publications:

  • HopkinsGroom: Q05513

    • Version: 11-September-2012

    Alternate Names:
    5590 Entrez Gene Id
    Q05513 Uniprot Accession
    PROTEIN KINASE C ZETA TYPE Uniprot Protein Name

    Gene Info:
    Interpro Type Domain
    Human Readable Name DRUGGABLE GENOME
    Interpro Acc IPR002290

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

  • MyCancerGenome: PRKCZ

    • Version: 20-Jun-2017

    Alternate Names:
    5590 Entrez Gene Id
    PRKCZ MyCancerGenome Gene Symbol
    PKC MyCancerGenome Reported Gene Name

    Gene Info:

    Publications:

  • ChemblInteractions: PKC2

    • Version: chembl_23

    Alternate Names:
    PKC2 GENE_SYMBOL
    PRKCZ GENE_SYMBOL
    Protein kinase C zeta type UNIPROT

    Gene Info:

    Publications:

  • HingoraniCasas: ENSG00000067606

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000067606 Gene Symbol
    PRKCZ Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • GO: PRKCZ

    • Version: 01-February-2022

    Alternate Names:
    PKC2 GO Gene Synonym

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE

    Publications:

  • dGene: PRKCZ

    • Version: 27-Jun-2013

    Alternate Names:
    5590 Gene ID
    PKC-ZETA dGene Synonym
    PKC2 dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

  • TTD: Protein kinase C zeta

    • Version: 2020.06.01

    Alternate Names:
    PRKCZ TTD Gene Abbreviation
    T59190 TTD Target ID

    Gene Info:

    Publications:

  • Pharos: PRKCZ

    • Version: 01-February-2022

    Alternate Names:
    Protein kinase C zeta type Gene Name
    Q05513 UniProt ID

    Gene Info:

    Gene Categories:
    TRANSPORTER, KINASE

    Publications:

  • DTC: PRKCZ

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications: