PTGDR2 Gene Record

  • PTGDR2 11251 Druggable Genome

    Alternate Names:

    11251
    PROSTAGLANDIN D2 RECEPTOR 2
    PTGDR2
    CD294
    CRTH2
    DL1R
    DP2
    GPR44
    604837
    4502
    ENSG00000183134
    OTTHUMG00000167796
    PD2R2_HUMAN
    Q9Y5Y4
    PUTATIVE G-PROTEIN COUPLED RECEPTOR 44 (CHEMOATTRACTANT RECEPTOR- HOMOLOGOUS MOLECULE EXPRESSED ON TH2 CELLS). [SOURCE:UNIPROT/SWISSPROT;ACC:Q9Y5Y4]
    CHEMOATTRACTANT RECEPTOR-HOMOLOGOUS MOLECULE EXPRESSED ON TH2 CELLS
    CD_antigen=CD294
    G-protein coupled receptor 44
    PD2R2
    T61722

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Interpro Type Family
    Interpro Name GPCR, rhodopsin-like, 7TM
    Interpro Short Name 7TM_GPCR_Rhodpsn
    Interpro Acc IPR000276
    Uniprot Status Swiss-Prot
    Human Readable Name G PROTEIN COUPLED RECEPTOR
    Uniprot Evidence 1: Evidence at protein level
    Target Class Receptors
    Target Subclass GPCR
    Target Subclass Rhodopsin
    Gene Biotype PROTEIN_CODING
    (7 More Sources)

    Gene Categories: Category Details

    KINASE
    G PROTEIN COUPLED RECEPTOR
    DRUGGABLE GENOME

    Publications:

  • AM-211   PTGDR2

    Interaction Score: 11.59

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction G protein-coupled receptor 44 antagonist
    Direct Interaction yes
    Trial Name AM-211

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial ChemblInteractions TTD

  • OC000459   PTGDR2

    Interaction Score: 11.59

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction G protein-coupled receptor 44 antagonist
    Direct Interaction yes
    Trial Name OC000459

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial ChemblInteractions TTD

  • ADC3680   PTGDR2

    Interaction Score: 7.73

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction G protein-coupled receptor 44 antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions TTD

  • MK-7246   PTGDR2

    Interaction Score: 7.73

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction G protein-coupled receptor 44 antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions TTD

  • ARRY-502   PTGDR2

    Interaction Score: 7.73

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction G protein-coupled receptor 44 antagonist

    PMIDs:
    None found


    Sources:
    ChemblInteractions TTD

  • AZD1981   PTGDR2

    Interaction Score: 7.73

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction G protein-coupled receptor 44 antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions TTD

  • QAV680   PTGDR2

    Interaction Score: 7.73

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction G protein-coupled receptor 44 antagonist

    PMIDs:
    None found


    Sources:
    ChemblInteractions TTD

  • SETIPIPRANT   PTGDR2

    Interaction Score: 3.86

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction G protein-coupled receptor 44 antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions TTD

  • RG7185   PTGDR2

    Interaction Score: 3.86

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction G protein-coupled receptor 44 antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • VIDUPIPRANT   PTGDR2

    Interaction Score: 3.86

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction G protein-coupled receptor 44 antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    DTC ChemblInteractions

  • AM-461   PTGDR2

    Interaction Score: 3.86

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction G protein-coupled receptor 44 antagonist

    PMIDs:
    None found


    Sources:
    ChemblInteractions TTD

  • MK-1029   PTGDR2

    Interaction Score: 1.93

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction G protein-coupled receptor 44 antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • FEVIPIPRANT   PTGDR2

    Interaction Score: 1.93

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction G protein-coupled receptor 44 antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • RAMATROBAN   PTGDR2

    Interaction Score: 1.55

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:

    PMIDs:
    16256979


    Sources:
    TTD

  • DONITRIPTAN   PTGDR2

    Interaction Score: 1.29

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction G protein-coupled receptor 44 antagonist

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • LAROPIPRANT   PTGDR2

    Interaction Score: 0.55

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Ensembl: ENSG00000183134

    • Version: 101_38

    Alternate Names:
    PTGDR2 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • RussLampel: ENSG00000183134

    • Version: 26-July-2011

    Alternate Names:
    GPR44 Display Id
    ENSG00000183134 Ensembl Gene Id
    PUTATIVE G-PROTEIN COUPLED RECEPTOR 44 (CHEMOATTRACTANT RECEPTOR- HOMOLOGOUS MOLECULE EXPRESSED ON TH2 CELLS). [SOURCE:UNIPROT/SWISSPROT;ACC:Q9Y5Y4] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HopkinsGroom: Q9Y5Y4

    • Version: 11-September-2012

    Alternate Names:
    PD2R2_HUMAN Uniprot Id
    PTGDR2 Uniprot Gene Name
    Q9Y5Y4 Uniprot Accession

    Gene Info:
    Interpro Type Family
    Interpro Name GPCR, rhodopsin-like, 7TM
    Interpro Short Name 7TM_GPCR_Rhodpsn

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR, DRUGGABLE GENOME

    Publications:

  • TdgClinicalTrial: Q9Y5Y4

    • Version: January-2014

    Alternate Names:
    GPR44 Gene Symbol
    PD2R2 Gene Symbol

    Gene Info:
    Target Class Receptors
    Target Subclass GPCR
    Target Subclass Rhodopsin

    Publications:

  • HingoraniCasas: ENSG00000183134

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000183134 Gene Symbol
    PTGDR2 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • ChemblInteractions: CRTH2

    • Version: chembl_23

    Alternate Names:
    DL1R GENE_SYMBOL
    GPR44 GENE_SYMBOL
    PTGDR2 GENE_SYMBOL

    Gene Info:

    Publications:

  • GO: PTGDR2

    • Version: 01-February-2022

    Alternate Names:
    CRTH2 GO Gene Synonym
    DL1R GO Gene Synonym
    GPR44 GO Gene Synonym

    Gene Info:

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR

    Publications:

  • dGene: PTGDR2

    • Version: 27-Jun-2013

    Alternate Names:
    11251 Gene ID
    CD294 dGene Synonym
    CRTH2 dGene Synonym

    Gene Info:

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR

    Publications:

  • TTD: Prostaglandin D2 receptor 2

    • Version: 2020.06.01

    Alternate Names:
    PTGDR2 TTD Gene Abbreviation
    T61722 TTD Target ID

    Gene Info:

    Publications:

  • Pharos: PTGDR2

    • Version: 01-February-2022

    Alternate Names:
    Prostaglandin D2 receptor 2 Gene Name
    Q9Y5Y4 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

  • DTC: PTGDR2

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications: