PTK6 Gene Record

  • PTK6 5753 Druggable Genome

    Alternate Names:

    5753
    PROTEIN TYROSINE KINASE 6
    PTK6
    BRK
    602004
    9617
    ENSG00000101213
    OTTHUMG00000033039
    Q13882
    PTK6_HUMAN
    PROTEIN-TYROSINE KINASE 6
    Breast tumor kinase
    Tyrosine-protein kinase BRK
    TYROSINE-PROTEIN KINASE 6 (EC 2.7.1.112) (BREAST TUMOR KINASE) (TYROSINE-PROTEIN KINASE BRK). [SOURCE:UNIPROT/SWISSPROT;ACC:Q13882]
    T73694

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Uniprot Evidence 1: Evidence at protein level
    Interpro Name Serine-threonine/tyrosine-protein kinase catalytic domain
    Uniprot Status Swiss-Prot
    Interpro Type Domain
    Interpro Short Name Ser-Thr/Tyr_kinase_cat_dom
    Interpro Acc IPR001245
    Human Readable Name KINASE
    Gene Biotype PROTEIN_CODING
    (6 More Sources)

    Gene Categories: Category Details

    KINASE
    TYROSINE KINASE
    DRUGGABLE GENOME
    TRANSCRIPTION FACTOR

    Publications:

  • SB-202190   PTK6

    Interaction Score: 0.44

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22951114


    Sources:
    DTC

  • TAK-715   PTK6

    Interaction Score: 0.34

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • OSI-632   PTK6

    Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CEDIRANIB   PTK6

    Interaction Score: 0.17

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • VANDETANIB   PTK6

    Interaction Score: 0.14

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Tyrosine-protein kinase BRK inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • DASATINIB   PTK6

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • R-406   PTK6

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TAE-684   PTK6

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Ensembl: ENSG00000101213

    • Version: 101_38

    Alternate Names:
    PTK6 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • RussLampel: ENSG00000101213

    • Version: 26-July-2011

    Alternate Names:
    TYROSINE-PROTEIN KINASE 6 (EC 2.7.1.112) (BREAST TUMOR KINASE) (TYROSINE-PROTEIN KINASE BRK). [SOURCE:UNIPROT/SWISSPROT;ACC:Q13882] Description
    PTK6 Display Id
    ENSG00000101213 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HopkinsGroom: Q13882

    • Version: 11-September-2012

    Alternate Names:
    PTK6_HUMAN Uniprot Id
    ENSG00000101213 Ensembl Gene Id
    PROTEIN-TYROSINE KINASE 6 Uniprot Protein Name

    Gene Info:
    Human Readable Name DRUGGABLE GENOME
    Uniprot Evidence 1: Evidence at protein level
    Interpro Name Serine-threonine/tyrosine-protein kinase catalytic domain

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

  • DTC: PTK6

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Selig R et al., 2012, A frozen analogue approach to aminopyridinylimidazoles leading to novel and promising p38 MAP kinase inhibitors., J Med Chem

  • ChemblInteractions: BRK

    • Version: chembl_23

    Alternate Names:
    BRK GENE_SYMBOL
    PTK6 GENE_SYMBOL
    Protein-tyrosine kinase 6 UNIPROT

    Gene Info:

    Publications:

  • HingoraniCasas: ENSG00000101213

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000101213 Gene Symbol
    PTK6 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • GO: PTK6

    • Version: 01-February-2022

    Alternate Names:
    BRK GO Gene Synonym

    Gene Info:

    Gene Categories:
    TYROSINE KINASE

    Publications:

  • dGene: PTK6

    • Version: 27-Jun-2013

    Alternate Names:
    5753 Gene ID
    BRK dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, TYROSINE KINASE

    Publications:

  • TTD: Tyrosine-protein kinase BRK

    • Version: 2020.06.01

    Alternate Names:
    PTK6 TTD Gene Abbreviation
    T73694 TTD Target ID

    Gene Info:

    Publications:

  • Pharos: PTK6

    • Version: 01-February-2022

    Alternate Names:
    Protein-tyrosine kinase 6 Gene Name
    Q13882 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE, TRANSCRIPTION FACTOR

    Publications: