DGIdb - PTPN12 Gene Record

PTPN12 5782 Druggable Genome

Alternate Names:

5782
PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 12
PTPN12
PTP-PEST
PTPG1
600079
9645
ENSG00000127947
OTTHUMG00000023501
Q05209
PTN12_HUMAN
TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 12
TYROSINE-PROTEIN PHOSPHATASE, NON-RECEPTOR TYPE 12 (EC 3.1.3.48) (PROTEIN-TYROSINE PHOSPHATASE G1) (PTPG1). [SOURCE:UNIPROT/SWISSPROT;ACC:Q05209]
4686
PROTEIN TYROSINE PHOSPHATASE NON-RECEPTOR TYPE 12

Gene Info:

Human Readable Name	PROTEIN PHOSPHATASE
Interpro Type	Domain
Interpro Name	Protein-tyrosine/Dual-specificity phosphatase
Interpro Acc	IPR000387
Human Readable Name	DRUGGABLE GENOME
Uniprot Status	Swiss-Prot
Uniprot Evidence	1: Evidence at protein level
Interpro Short Name	Tyr/Dual-specificity_Pase
Gene Biotype	PROTEIN_CODING

(5 More Sources)

Gene Categories: Category Details

PROTEIN PHOSPHATASE
KINASE
DRUGGABLE GENOME

Publications:

Nair A et al., 2018, Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer., Nat Med

CHEMBL601167 PTPN12

Interaction Score: 5.15

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CRIZOTINIB PTPN12

Interaction Score: 2.29

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
29578538

Sources:
CIViC
SUNITINIB PTPN12

Interaction Score: 1.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
29578538

Sources:
CIViC

Ensembl: ENSG00000127947
- Version: 101_38
Alternate Names:

PTPN12 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
HopkinsGroom: Q05209
- Version: 11-September-2012
Alternate Names:

PTN12_HUMAN Uniprot Id

ENSG00000127947 Ensembl Gene Id

Q05209 Uniprot Accession

Gene Info:

Interpro Type Domain

Interpro Name Protein-tyrosine/Dual-specificity phosphatase

Interpro Acc IPR000387

Gene Categories:

PROTEIN PHOSPHATASE, DRUGGABLE GENOME

Publications:

RussLampel: ENSG00000127947

Version: 26-July-2011

Alternate Names:

TYROSINE-PROTEIN PHOSPHATASE, NON-RECEPTOR TYPE 12 (EC 3.1.3.48) (PROTEIN-TYROSINE PHOSPHATASE G1) (PTPG1). [SOURCE:UNIPROT/SWISSPROT;ACC:Q05209] Description

PTPN12 Display Id

ENSG00000127947 Ensembl Gene Id

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:

CIViC: PTPN12
- Version: 14-September-2020
Alternate Names:

5782 Entrez Gene ID

4686 CIViC Gene ID

Gene Info:

Publications:

Nair A et al., 2018, Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer., Nat Med
HingoraniCasas: ENSG00000127947
- Version: 31-May-2017
Alternate Names:

ENSG00000127947 Gene Symbol

PTPN12 Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
dGene: PTPN12
- Version: 27-Jun-2013
Alternate Names:

5782 Gene ID

PTP-PEST dGene Synonym

PTPG1 dGene Synonym

Gene Info:

Gene Categories:

PROTEIN PHOSPHATASE

Publications:
Pharos: PTPN12
- Version: 01-February-2022
Alternate Names:

Tyrosine-protein phosphatase non-receptor type 12 Gene Name

Q05209 UniProt ID

Gene Info:

Gene Categories:

KINASE

Publications:
DTC: PTPN12
- Version: 02-September-2020
Alternate Names:

Gene Info:

Publications:
GO: PTPN12
- Version: 01-February-2022
Alternate Names:

Gene Info:

Gene Categories:

PROTEIN PHOSPHATASE

Publications:

PTN12_HUMAN	Uniprot Id
ENSG00000127947	Ensembl Gene Id
Q05209	Uniprot Accession

TYROSINE-PROTEIN PHOSPHATASE, NON-RECEPTOR TYPE 12 (EC 3.1.3.48) (PROTEIN-TYROSINE PHOSPHATASE G1) (PTPG1). [SOURCE:UNIPROT/SWISSPROT;ACC:Q05209]	Description
PTPN12	Display Id
ENSG00000127947	Ensembl Gene Id

Tyrosine-protein phosphatase non-receptor type 12	Gene Name
Q05209	UniProt ID

5782	Gene ID
PTP-PEST	dGene Synonym
PTPG1	dGene Synonym

PTPN12 Gene Record

PTPN12 5782 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

CHEMBL601167 PTPN12

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

CRIZOTINIB PTPN12

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 29578538

Sources: CIViC

SUNITINIB PTPN12

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 29578538

Sources: CIViC

Ensembl: ENSG00000127947

Alternate Names: PTPN12 Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

HopkinsGroom: Q05209

Alternate Names: PTN12_HUMAN Uniprot Id ENSG00000127947 Ensembl Gene Id Q05209 Uniprot Accession

Gene Info: Interpro Type Domain Interpro Name Protein-tyrosine/Dual-specificity phosphatase Interpro Acc IPR000387

Gene Categories: PROTEIN PHOSPHATASE, DRUGGABLE GENOME

Publications:

RussLampel: ENSG00000127947

Alternate Names: TYROSINE-PROTEIN PHOSPHATASE, NON-RECEPTOR TYPE 12 (EC 3.1.3.48) (PROTEIN-TYROSINE PHOSPHATASE G1) (PTPG1). [SOURCE:UNIPROT/SWISSPROT;ACC:Q05209] Description PTPN12 Display Id ENSG00000127947 Ensembl Gene Id

Gene Info: Human Readable Name DRUGGABLE GENOME

Gene Categories: DRUGGABLE GENOME

Publications:

CIViC: PTPN12

Alternate Names: 5782 Entrez Gene ID 4686 CIViC Gene ID

Gene Info:

Publications: Nair A et al., 2018, Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer., Nat Med

HingoraniCasas: ENSG00000127947

Alternate Names: ENSG00000127947 Gene Symbol PTPN12 Ensembl Id

Gene Info:

Gene Categories: DRUGGABLE GENOME

Publications:

dGene: PTPN12

Alternate Names: 5782 Gene ID PTP-PEST dGene Synonym PTPG1 dGene Synonym

Gene Info:

Gene Categories: PROTEIN PHOSPHATASE

Publications:

Pharos: PTPN12

Alternate Names: Tyrosine-protein phosphatase non-receptor type 12 Gene Name Q05209 UniProt ID

Gene Info:

Gene Categories: KINASE

Publications:

DTC: PTPN12

Alternate Names:

Gene Info:

Publications:

GO: PTPN12

Alternate Names:

Gene Info:

Gene Categories: PROTEIN PHOSPHATASE

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
29578538

Sources:
CIViC

Interaction Types & Directionality:

n/a

PMIDs:
29578538

Sources:
CIViC

Alternate Names:

PTPN12 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

PTN12_HUMAN Uniprot Id

ENSG00000127947 Ensembl Gene Id

Q05209 Uniprot Accession

Gene Info:

Interpro Type Domain

Interpro Name Protein-tyrosine/Dual-specificity phosphatase

Interpro Acc IPR000387

Gene Categories:

PROTEIN PHOSPHATASE, DRUGGABLE GENOME

Alternate Names:

TYROSINE-PROTEIN PHOSPHATASE, NON-RECEPTOR TYPE 12 (EC 3.1.3.48) (PROTEIN-TYROSINE PHOSPHATASE G1) (PTPG1). [SOURCE:UNIPROT/SWISSPROT;ACC:Q05209] Description

PTPN12 Display Id

ENSG00000127947 Ensembl Gene Id

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

5782 Entrez Gene ID

4686 CIViC Gene ID

Publications:

Nair A et al., 2018, Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer., Nat Med

Alternate Names:

ENSG00000127947 Gene Symbol

PTPN12 Ensembl Id

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

5782 Gene ID

PTP-PEST dGene Synonym

PTPG1 dGene Synonym

Gene Categories:

PROTEIN PHOSPHATASE

Alternate Names:

Tyrosine-protein phosphatase non-receptor type 12 Gene Name

Q05209 UniProt ID

Gene Categories:

KINASE

Gene Categories:

PROTEIN PHOSPHATASE