5914 |
RETINOIC ACID RECEPTOR ALPHA |
RARA |
NR1B1 |
RAR |
180240 |
9864 |
ENSG00000131759 |
OTTHUMG00000133328 |
Nuclear receptor subfamily 1 group B member 1 |
RAR-alpha |
P10276 |
RARA_HUMAN |
RETINOIC ACID RECEPTOR ALPHA (RAR-ALPHA). [SOURCE:UNIPROT/SWISSPROT;ACC:P10276] |
PA34225 |
T94085 |
RARalpha |
Target Class | Receptors |
Target Subclass | Nuclear receptor |
Human Readable Name | DRUGGABLE GENOME |
Interpro Name | Nuclear hormone receptor, ligand-binding, core |
Uniprot Status | Swiss-Prot |
Human Readable Name | NUCLEAR HORMONE RECEPTOR |
Interpro Acc | IPR000536 |
Interpro Short Name | Nucl_hrmn_rcpt_lig-bd_core |
Interpro Type | Domain |
Uniprot Evidence | 1: Evidence at protein level |
Initial Gene Query | NR1B1 |
Counted Citations from 1950-2000 | 2172 |
Target Main Class | Receptors |
Gene Biotype | PROTEIN_CODING |
TRANSCRIPTION FACTOR COMPLEX |
CELL SURFACE |
NUCLEAR HORMONE RECEPTOR |
DRUGGABLE GENOME |
CLINICALLY ACTIONABLE |
agonist (activating) |
Mechanism of Interaction | Retinoic acid receptor alpha agonist |
Direct Interaction | yes |
agonist (activating) |
Novel drug target | Established target |
Trial Name | - |
Mechanism of Interaction | Retinoic acid receptor agonist |
agonist (activating) |
Mechanism of Interaction | Retinoic acid receptor agonist |
Direct Interaction | yes |
Trial Name | tazarotene,Tazorac |
agonist (activating) |
other/unknown |
Mechanism of Interaction | Retinoic acid receptor agonist |
Direct Interaction | yes |
Trial Name | CIP-isotretinoin |
agonist (activating) |
Trial Name | - |
Novel drug target | Established target |
Mechanism of Interaction | Retinoid receptor agonist |
antagonist (inhibitory) |
Mechanism of Interaction | Retinoic acid receptor antagonist |
Direct Interaction | yes |
modulator |
Mechanism of Interaction | Retinoid receptor modulator |
Direct Interaction | yes |
n/a |
Trial Name | fenretinide, RT-101 |
Novel drug target | Established target |
RARA | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
5914 | Entrez Gene ID |
Initial Gene Query | NR1B1 |
Counted Citations from 1950-2000 | 2172 |
NUCLEAR HORMONE RECEPTOR |
P10276 | Uniprot Accession |
RARA | Gene Symbol |
5914 | Entrez Gene Id |
Target Subclass | Nuclear receptor |
Target Main Class | Receptors |
RARA | Display Id |
RETINOIC ACID RECEPTOR ALPHA (RAR-ALPHA). [SOURCE:UNIPROT/SWISSPROT;ACC:P10276] | Description |
ENSG00000131759 | Ensembl Gene Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
5914 | Entrez Gene Id |
RARA_HUMAN | Uniprot Id |
ENSG00000131759 | Ensembl Gene Id |
Interpro Name | Nuclear hormone receptor, ligand-binding, core |
Uniprot Status | Swiss-Prot |
Human Readable Name | NUCLEAR HORMONE RECEPTOR |
NUCLEAR HORMONE RECEPTOR, DRUGGABLE GENOME |
RARA | Gene Symbol |
Target Class | Receptors |
Target Subclass | Nuclear receptor |
ENSG00000131759 | Gene Symbol |
RARA | Ensembl Id |
DRUGGABLE GENOME |
NR1B1 | GENE_SYMBOL |
RARA | GENE_SYMBOL |
Retinoic acid receptor alpha | UNIPROT |
PA34225 | PharmGKB ID |
NR1B1 | GO Gene Synonym |
TRANSCRIPTION FACTOR COMPLEX, CELL SURFACE, NUCLEAR HORMONE RECEPTOR |
RARA | Gene Symbol |
CLINICALLY ACTIONABLE |
5914 | Gene ID |
NR1B1 | dGene Synonym |
RAR | dGene Synonym |
NUCLEAR HORMONE RECEPTOR |
RARA | TTD Gene Abbreviation |
T94085 | TTD Target ID |
CLINICALLY ACTIONABLE |
CLINICALLY ACTIONABLE |
CLINICALLY ACTIONABLE |