5915 |
RETINOIC ACID RECEPTOR BETA |
RARB |
HAP |
MCOPS12 |
NR1B2 |
RARbeta1 |
RRB2 |
180220 |
9865 |
ENSG00000077092 |
OTTHUMG00000130480 |
HBV-activated protein |
Nuclear receptor subfamily 1 group B member 2 |
RAR-epsilon |
RAR-beta |
51401 |
RETINOIC ACID RECEPTOR BETA (RAR-BETA) (RAR-EPSILON) (HBV-ACTIVATED PROTEIN). [SOURCE:UNIPROT/SWISSPROT;ACC:P10826] |
P10826 |
RARB_HUMAN |
T61657 |
RARbeta |
Initial Gene Query | NR1B2 |
Counted Citations from 1950-2000 | 1251 |
Human Readable Name | DRUGGABLE GENOME |
Target Main Class | Receptors |
Target Subclass | Nuclear receptor |
Target Class | Receptors |
Human Readable Name | NUCLEAR HORMONE RECEPTOR |
Uniprot Evidence | 1: Evidence at protein level |
Uniprot Status | Swiss-Prot |
Interpro Type | Domain |
Interpro Short Name | Nucl_hrmn_rcpt_lig-bd_core |
Interpro Acc | IPR000536 |
Interpro Name | Nuclear hormone receptor, ligand-binding, core |
Gene Biotype | PROTEIN_CODING |
NUCLEAR HORMONE RECEPTOR |
DRUGGABLE GENOME |
agonist (activating) |
Trial Name | - |
Novel drug target | Established target |
Mechanism of Interaction | Retinoic acid receptor agonist |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Retinoic acid receptor agonist |
Novel drug target | Established target |
agonist (activating) |
Mechanism of Interaction | Retinoid receptor agonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Retinoic acid receptor antagonist |
Direct Interaction | yes |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Retinoid receptor agonist |
modulator |
Direct Interaction | yes |
Mechanism of Interaction | Retinoid receptor modulator |
agonist (activating) |
Mechanism of Interaction | Retinoic acid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Retinoic acid receptor agonist |
Direct Interaction | yes |
n/a |
Trial Name | fenretinide, RT-101 |
Novel drug target | Established target |
RARB | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
5915 | Entrez Gene Id |
ENSG00000077092 | Ensembl Gene Id |
RARB_HUMAN | Uniprot Id |
Uniprot Evidence | 1: Evidence at protein level |
Uniprot Status | Swiss-Prot |
Interpro Type | Domain |
NUCLEAR HORMONE RECEPTOR, DRUGGABLE GENOME |
RARB | Gene Symbol |
Target Class | Receptors |
Target Subclass | Nuclear receptor |
ENSG00000077092 | Ensembl Gene Id |
RARB | Display Id |
RETINOIC ACID RECEPTOR BETA (RAR-BETA) (RAR-EPSILON) (HBV-ACTIVATED PROTEIN). [SOURCE:UNIPROT/SWISSPROT;ACC:P10826] | Description |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
5915 | Entrez Gene Id |
RARB | Gene Symbol |
RARB_HUMAN | Uniprot Id |
Target Main Class | Receptors |
Target Subclass | Nuclear receptor |
51401 | Entrez Gene ID |
Initial Gene Query | NR1B2 |
Counted Citations from 1950-2000 | 1251 |
NUCLEAR HORMONE RECEPTOR |
ENSG00000077092 | Gene Symbol |
RARB | Ensembl Id |
DRUGGABLE GENOME |
NR1B2 | GENE_SYMBOL |
RARB | GENE_SYMBOL |
Retinoic acid receptor beta | UNIPROT |
HAP | GO Gene Synonym |
NR1B2 | GO Gene Synonym |
NUCLEAR HORMONE RECEPTOR |
5915 | Gene ID |
HAP | dGene Synonym |
NR1B2 | dGene Synonym |
NUCLEAR HORMONE RECEPTOR |
RARB | TTD Gene Abbreviation |
T61657 | TTD Target ID |