5972 |
RENIN |
REN |
HNFJ2 |
179820 |
9958 |
ENSG00000143839 |
OTTHUMG00000036059 |
P00797 |
PA297 |
RENI_HUMAN |
Angiotensinogenase |
RENIN PRECURSOR (EC 3.4.23.15) (ANGIOTENSINOGENASE). [SOURCE:UNIPROT/SWISSPROT;ACC:P00797] |
Angiotensinogenase renin |
T61622 |
ADTKD4 |
RTD |
Human Readable Name | PROTEASE |
Human Readable Name | DRUGGABLE GENOME |
Target Class | Enzymes |
Target Subclass | EC:3.4.23.15 |
Target Subclass | 3.4.23.15 |
Target Main Class | Enzymes |
Uniprot Status | Swiss-Prot |
Uniprot Evidence | 1: Evidence at protein level |
Interpro Short Name | Peptidase_aspartic_AS |
Interpro Type | Active_site |
Interpro Acc | IPR001969 |
Interpro Name | Peptidase aspartic, active site |
Gene Biotype | PROTEIN_CODING |
PROTEASE |
DRUGGABLE GENOME |
ENZYME |
n/a |
Trial Name | VTP-27999 |
Novel drug target | Established target |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Renin inhibitor |
REN | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
REN | Gene Symbol |
Target Class | Enzymes |
Target Subclass | EC:3.4.23.15 |
REN | Gene Symbol |
P00797 | Uniprot Accession |
5972 | Entrez Gene Id |
Target Subclass | 3.4.23.15 |
Target Main Class | Enzymes |
ENSG00000143839 | Ensembl Gene Id |
RENIN PRECURSOR (EC 3.4.23.15) (ANGIOTENSINOGENASE). [SOURCE:UNIPROT/SWISSPROT;ACC:P00797] | Description |
REN | Display Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
REN | Uniprot Gene Name |
RENI_HUMAN | Uniprot Id |
5972 | Entrez Gene Id |
Human Readable Name | DRUGGABLE GENOME |
Uniprot Status | Swiss-Prot |
Uniprot Evidence | 1: Evidence at protein level |
PROTEASE, DRUGGABLE GENOME |
PA297 | PharmGKB ID |
REN | TTD Gene Abbreviation |
T61622 | TTD Target ID |
ENSG00000143839 | Gene Symbol |
REN | Ensembl Id |
DRUGGABLE GENOME |
REN | GENE_SYMBOL |
Renin | UNIPROT |
Angiotensinogenase | UNIPROT |
5972 | Gene ID |
HNFJ2 | dGene Synonym |
PROTEASE |
Renin | Gene Name |
P00797 | UniProt ID |
ENZYME |
PROTEASE |