-
SCNN1A 6337 Druggable Genome
Alternate Names:
6337 SODIUM CHANNEL EPITHELIAL 1 ALPHA SUBUNIT SCNN1A BESC2 ENaCa ENaCalpha SCNEA SCNN1 600228 10599 ENSG00000111319 OTTHUMG00000168268 Amiloride-sensitive sodium channel subunit alpha Nonvoltage-gated sodium channel 1 subunit alpha Alpha-ENaC Alpha-NaCH Epithelial Na(+) channel subunit alpha SCNNA_HUMAN P37088 AMILORIDE-SENSITIVE SODIUM CHANNEL ALPHA-SUBUNIT (EPITHELIAL NA+ CHANNEL ALPHA SUBUNIT) (ALPHA ENAC) (NONVOLTAGE-GATED SODIUM CHANNEL 1 ALPHA SUBUNIT) (SCNEA) (ALPHA NACH). [SOURCE:UNIPROT/SWISSPROT;ACC:P37088] PA305 SODIUM CHANNEL EPITHELIAL 1 SUBUNIT ALPHA LIDLS3 Gene Info:
Target Class Transporters Target Subclass TC:1.A.6.1.1 Target Subclass Channels Transmembrane Helix Count 2 Target Main Class Transporters Target Subclass Amiloride-sensitive Na+ channel Human Readable Name ION CHANNEL Uniprot Evidence 1: Evidence at protein level Interpro Type Family Human Readable Name DRUGGABLE GENOME Uniprot Status Swiss-Prot Interpro Acc IPR001873 Interpro Name Na+ channel, amiloride-sensitive Interpro Short Name Na+channel_ASC Gene Biotype PROTEIN_CODING Gene Categories: Category Details
ION CHANNEL DRUGGABLE GENOME Publications:
-
Interaction Score: 8.59
Interaction Types & Directionality:
blocker (inhibitory) inhibitor (inhibitory) Interaction Info:
Direct Interaction yes Mechanism of Interaction Amiloride-sensitive sodium channel, ENaC blocker Trial Name -
Sources:
TdgClinicalTrial ChemblInteractions TEND PharmGKB -
Interaction Types & Directionality:
blocker (inhibitory) Interaction Info:
Mechanism of Interaction Amiloride-sensitive sodium channel, ENaC blocker Direct Interaction yes -
Interaction Score: 3.86
Interaction Types & Directionality:
blocker (inhibitory) Interaction Info:
Direct Interaction yes Mechanism of Interaction Amiloride-sensitive sodium channel, ENaC blocker
-
- Version: 101_38
Alternate Names:
SCNN1A Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
-
- Version: 26-July-2011
Alternate Names:
AMILORIDE-SENSITIVE SODIUM CHANNEL ALPHA-SUBUNIT (EPITHELIAL NA+ CHANNEL ALPHA SUBUNIT) (ALPHA ENAC) (NONVOLTAGE-GATED SODIUM CHANNEL 1 ALPHA SUBUNIT) (SCNEA) (ALPHA NACH). [SOURCE:UNIPROT/SWISSPROT;ACC:P37088] Description SCNN1A Display Id ENSG00000111319 Ensembl Gene Id Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
-
- Version: January-2014
Alternate Names:
SCNN1A Gene Symbol Gene Info:
Target Class Transporters Target Subclass TC:1.A.6.1.1 Publications:
-
Alternate Names:
6337 Entrez Gene Id P37088 Uniprot Accession SCNN1A Gene Symbol Gene Info:
Target Subclass Channels Transmembrane Helix Count 2 Target Main Class Transporters Publications:
-
- Version: 11-September-2012
Alternate Names:
AMILORIDE-SENSITIVE SODIUM CHANNEL SUBUNIT ALPHA Uniprot Protein Name ENSG00000111319 Ensembl Gene Id SCNN1A Uniprot Gene Name Gene Info:
Uniprot Evidence 1: Evidence at protein level Interpro Type Family Human Readable Name DRUGGABLE GENOME Gene Categories:
ION CHANNEL, DRUGGABLE GENOME Publications:
-
Alternate Names:
PA305 PharmGKB ID Gene Info:
-
- Version: 31-May-2017
Alternate Names:
ENSG00000111319 Gene Symbol SCNN1A Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
-
- Version: chembl_23
Alternate Names:
SCNN1 GENE_SYMBOL SCNN1A GENE_SYMBOL Amiloride-sensitive sodium channel subunit alpha UNIPROT Gene Info:
Publications:
-
Alternate Names:
Amiloride-sensitive sodium channel subunit alpha Gene Name P37088 UniProt ID Gene Info:
Gene Categories:
ION CHANNEL Publications: