SLC5A1 Gene Record

  • SLC5A1 6523 Druggable Genome

    Alternate Names:

    6523
    SOLUTE CARRIER FAMILY 5 MEMBER 1
    SLC5A1
    D22S675
    NAGT
    SGLT1
    182380
    11036
    ENSG00000100170
    OTTHUMG00000030768
    High affinity sodium-glucose cotransporter
    Sodium/glucose cotransporter 1
    Na(+)/glucose cotransporter 1
    P13866
    SODIUM/GLUCOSE COTRANSPORTER 1 (NA(+)/GLUCOSE COTRANSPORTER 1) (HIGH AFFINITY SODIUM-GLUCOSE COTRANSPORTER). [SOURCE:UNIPROT/SWISSPROT;ACC:P13866]
    T54771

    Gene Info:

    Target Class Transporters
    Target Subclass TC:2.A.21.3.1
    Target Subclass TC:2.A.21.3.16
    Human Readable Name DRUGGABLE GENOME
    Gene Biotype PROTEIN_CODING
    (6 More Sources)

    Gene Categories: Category Details

    TRANSPORTER
    EXTERNAL SIDE OF PLASMA MEMBRANE
    DRUGGABLE GENOME

    Publications:

  • GSK-1614235   SLC5A1

    Interaction Score: 12.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • SOTAGLIFLOZIN   SLC5A1

    Interaction Score: 8.24

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Sodium/glucose cotransporter 1 inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions TTD

  • LICOGLIFLOZIN   SLC5A1

    Interaction Score: 6.18

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • GLUFOSFAMIDE   SLC5A1

    Interaction Score: 1.55

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Novel drug target Novel Target
    Trial Name Glufosfamide

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • STREPTOZOCIN   SLC5A1

    Interaction Score: 0.54

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    1722397


    Sources:
    NCI

  • Ensembl: ENSG00000100170

    • Version: 101_38

    Alternate Names:
    SLC5A1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • RussLampel: ENSG00000100170

    • Version: 26-July-2011

    Alternate Names:
    SLC5A1 Display Id
    SODIUM/GLUCOSE COTRANSPORTER 1 (NA(+)/GLUCOSE COTRANSPORTER 1) (HIGH AFFINITY SODIUM-GLUCOSE COTRANSPORTER). [SOURCE:UNIPROT/SWISSPROT;ACC:P13866] Description
    ENSG00000100170 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • TdgClinicalTrial: P13866

    • Version: January-2014

    Alternate Names:
    SLC5A1 Gene Symbol

    Gene Info:
    Target Class Transporters
    Target Subclass TC:2.A.21.3.1
    Target Subclass TC:2.A.21.3.16

    Publications:

  • NCI: SLC5A1

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Miyamoto et al., 1991, Diabetes and glucose transporter gene expression in rat small intestine., Biochem. Biophys. Res. Commun.

  • HingoraniCasas: ENSG00000100170

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000100170 Gene Symbol
    SLC5A1 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • ChemblInteractions: NAGT

    • Version: chembl_23

    Alternate Names:
    SGLT1 GENE_SYMBOL
    SLC5A1 GENE_SYMBOL
    Sodium/glucose cotransporter 1 UNIPROT

    Gene Info:

    Publications:

  • HumanProteinAtlas: SLC5A1

    • Version: 19.3

    Alternate Names:
    ENSG00000100170 Ensembl Gene ID
    D22S675 Human Protein Atlas Gene Synonym
    NAGT Human Protein Atlas Gene Synonym

    Gene Info:

    Gene Categories:
    TRANSPORTER

    Publications:

  • GO: SLC5A1

    • Version: 01-February-2022

    Alternate Names:
    NAGT GO Gene Synonym
    SGLT1 GO Gene Synonym

    Gene Info:

    Gene Categories:
    EXTERNAL SIDE OF PLASMA MEMBRANE

    Publications:

  • TTD: Sodium/glucose cotransporter 1

    • Version: 2020.06.01

    Alternate Names:
    SGLT1 TTD Gene Abbreviation
    T54771 TTD Target ID

    Gene Info:

    Publications:

  • Pharos: SLC5A1

    • Version: 01-February-2022

    Alternate Names:
    Sodium/glucose cotransporter 1 Gene Name
    P13866 UniProt ID

    Gene Info:

    Gene Categories:
    TRANSPORTER

    Publications: