SLC5A2 Gene Record

  • EMPAGLIFLOZIN   SLC5A2

    Interaction Score: 7.73

    Interaction Types & Directionality:
    antagonist (inhibitory)
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name BI-10773
    Novel drug target Established target
    Mechanism of Interaction Sodium/glucose cotransporter 2 inhibitor

    PMIDs:
    25598831


    Sources:
    TdgClinicalTrial ChemblInteractions

  • DAPAGLIFLOZIN PROPYLENE GLYCOL   SLC5A2

    Interaction Score: 5.15

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Sodium/glucose cotransporter 2 inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • CANAGLIFLOZIN   SLC5A2

    Interaction Score: 5.15

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Sodium/glucose cotransporter 2 inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • BEXAGLIFLOZIN   SLC5A2

    Interaction Score: 5.15

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Sodium/glucose cotransporter 2 inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • REMOGLIFLOZIN ETABONATE   SLC5A2

    Interaction Score: 5.15

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Sodium/glucose cotransporter 2 inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • DAPAGLIFLOZIN   SLC5A2

    Interaction Score: 5.15

    Interaction Types & Directionality:
    antagonist (inhibitory)
    inhibitor (inhibitory)

    Interaction Info:
    Novel drug target Established target
    Trial Name BMS-512148, dapagliflozin

    PMIDs:
    19996149


    Sources:
    TdgClinicalTrial

  • IPRAGLIFLOZIN   SLC5A2

    Interaction Score: 5.15

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name ASP1941
    Novel drug target Established target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • ERTUGLIFLOZIN   SLC5A2

    Interaction Score: 5.15

    Interaction Types & Directionality:
    antagonist (inhibitory)
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Sodium/glucose cotransporter 2 inhibitor
    Direct Interaction yes

    PMIDs:
    23169609


    Sources:
    ChemblInteractions

  • CANAGLIFLOZIN   SLC5A2

    Interaction Score: 5.15

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Novel drug target Established target
    Trial Name Canagliflozin

    PMIDs:
    23590413


    Sources:
    TdgClinicalTrial

  • TOFOGLIFLOZIN   SLC5A2

    Interaction Score: 2.58

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Sodium/glucose cotransporter 2 inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • SOTAGLIFLOZIN   SLC5A2

    Interaction Score: 1.72

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Sodium/glucose cotransporter 2 inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GLUFOSFAMIDE   SLC5A2

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name Glufosfamide
    Novel drug target Established target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • Ensembl: ENSG00000140675

    • Version: 101_38

    Alternate Names:
    SLC5A2 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • RussLampel: ENSG00000140675

    • Version: 26-July-2011

    Alternate Names:
    SLC5A2 Display Id
    SODIUM/GLUCOSE COTRANSPORTER 2 (NA(+)/GLUCOSE COTRANSPORTER 2) (LOW AFFINITY SODIUM-GLUCOSE COTRANSPORTER). [SOURCE:UNIPROT/SWISSPROT;ACC:P31639] Description
    ENSG00000140675 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • TdgClinicalTrial: Q9HAB3

    • Version: January-2014

    Alternate Names:
    SLC5A2 Gene Symbol

    Gene Info:
    Target Class Transporter
    Target Subclass TC:9.A.53.1.3

    Publications:

  • TdgClinicalTrial: P31639

    • Version: January-2014

    Alternate Names:
    SLC5A2 Gene Symbol

    Gene Info:
    Target Class Transporters
    Target Subclass TC:2.A.21.3.16

    Publications:

  • ChemblInteractions: SGLT2

    • Version: chembl_23

    Alternate Names:
    SGLT2 GENE_SYMBOL
    SLC5A2 GENE_SYMBOL
    Sodium/glucose cotransporter 2 UNIPROT

    Gene Info:

    Publications:

  • HingoraniCasas: ENSG00000140675

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000140675 Gene Symbol
    SLC5A2 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • GO: SLC5A2

    • Version: 01-February-2022

    Alternate Names:
    SGLT2 GO Gene Synonym

    Gene Info:

    Gene Categories:
    EXTERNAL SIDE OF PLASMA MEMBRANE

    Publications:

  • Pharos: SLC5A2

    • Version: 01-February-2022

    Alternate Names:
    Sodium/glucose cotransporter 2 Gene Name
    P31639 UniProt ID

    Gene Info:

    Gene Categories:
    TRANSPORTER

    Publications: