7015 |
TELOMERASE REVERSE TRANSCRIPTASE |
TERT |
CMM9 |
DKCA2 |
DKCB4 |
EST2 |
PFBMFT1 |
TCS1 |
TP2 |
TRT |
hEST2 |
hTRT |
187270 |
11730 |
ENSG00000164362 |
OTTHUMG00000090357 |
TELOMERASE REVERSE TRANSCRIPTASE (EC 2.7.7.49) (TELOMERASE CATALYTIC SUBUNIT) (HEST2) (TELOMERASE-ASSOCIATED PROTEIN 2) (TP2). [SOURCE:UNIPROT/SWISSPROT;ACC:O14746] |
O14746 |
TERT_HUMAN |
Telomerase catalytic subunit |
Telomerase-associated protein 2 |
79 |
T86052 |
Human Readable Name | DRUGGABLE GENOME |
Interpro Name | Reverse transcriptase |
Uniprot Evidence | 1: Evidence at protein level |
Interpro Short Name | RVT |
Interpro Acc | IPR000477 |
Uniprot Status | Swiss-Prot |
Interpro Type | Domain |
Target Class | Enzymes |
Target Subclass | EC:2.7.7.49 |
Gene Biotype | PROTEIN_CODING |
DRUG RESISTANCE |
DRUGGABLE GENOME |
RNA DIRECTED DNA POLYMERASE |
CLINICALLY ACTIONABLE |
ENZYME |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Telomerase reverse transcriptase inhibitor |
Trial Name | Imetelstat |
n/a |
Trial Name | GV1001 |
Novel drug target | Novel Target |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Telomerase reverse transcriptase inhibitor |
TERT | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
TERT | Gene Symbol |
Target Class | Enzymes |
Target Subclass | EC:2.7.7.49 |
TERT | Display Id |
ENSG00000164362 | Ensembl Gene Id |
TELOMERASE REVERSE TRANSCRIPTASE (EC 2.7.7.49) (TELOMERASE CATALYTIC SUBUNIT) (HEST2) (TELOMERASE-ASSOCIATED PROTEIN 2) (TP2). [SOURCE:UNIPROT/SWISSPROT;ACC:O14746] | Description |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
TERT | Uniprot Gene Name |
O14746 | Uniprot Accession |
7015 | Entrez Gene Id |
Interpro Name | Reverse transcriptase |
Uniprot Evidence | 1: Evidence at protein level |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
7015 | Entrez Gene ID |
79 | CIViC Gene ID |
DRUG RESISTANCE |
ENSG00000164362 | Gene Symbol |
TERT | Ensembl Id |
DRUGGABLE GENOME |
TCS1 | GENE_SYMBOL |
TRT | GENE_SYMBOL |
TERT | GENE_SYMBOL |
ENSG00000164362 | Ensembl Gene ID |
EST2 | Human Protein Atlas Gene Synonym |
hEST2 | Human Protein Atlas Gene Synonym |
ENZYME |
EST2 | GO Gene Synonym |
TCS1 | GO Gene Synonym |
TRT | GO Gene Synonym |
RNA DIRECTED DNA POLYMERASE |
TERT | TTD Gene Abbreviation |
T86052 | TTD Target ID |
Telomerase reverse transcriptase | Gene Name |
O14746 | UniProt ID |
ENZYME |
CLINICALLY ACTIONABLE |
CLINICALLY ACTIONABLE |
CLINICALLY ACTIONABLE |
CLINICALLY ACTIONABLE |