TNK2 Gene Record

  • TNK2 10188 Druggable Genome

    Alternate Names:

    10188
    TYROSINE KINASE NON RECEPTOR 2
    TNK2
    ACK
    ACK-1
    ACK1
    p21cdc42Hs
    606994
    19297
    ENSG00000061938
    OTTHUMG00000155737
    Q07912
    ACTIVATED CDC42 KINASE 1 (EC 2.7.1.112) (ACK-1) (TYROSINE KINASE NON- RECEPTOR PROTEIN 2). [SOURCE:UNIPROT/SWISSPROT;ACC:Q07912]
    ACTIVATED CDC42 KINASE 1
    ACK1_HUMAN
    T63220

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Uniprot Status Swiss-Prot
    Interpro Acc IPR001245
    Interpro Name Serine-threonine/tyrosine-protein kinase catalytic domain
    Interpro Type Domain
    Interpro Short Name Ser-Thr/Tyr_kinase_cat_dom
    Uniprot Evidence 1: Evidence at protein level
    Human Readable Name KINASE
    Gene Biotype PROTEIN_CODING
    (5 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    TYROSINE KINASE
    DRUGGABLE GENOME

    Publications:

  • CHEMBL202721   TNK2

    Interaction Score: 0.2

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL406845   TNK2

    Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ADAVOSERTIB   TNK2

    Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PAZOPANIB   TNK2

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL1997335   TNK2

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ALISERTIB   TNK2

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL379975   TNK2

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PD-0166285   TNK2

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ENTRECTINIB   TNK2

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • GEFITINIB   TNK2

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • DASATINIB   TNK2

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • R-406   TNK2

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RG-1530   TNK2

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CYC-116   TNK2

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TAE-684   TNK2

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PF-00562271   TNK2

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ILORASERTIB   TNK2

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CENISERTIB   TNK2

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Ensembl: ENSG00000061938

    • Version: 101_38

    Alternate Names:
    TNK2 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • HopkinsGroom: Q07912

    • Version: 11-September-2012

    Alternate Names:
    TNK2 Uniprot Gene Name
    ACK1_HUMAN Uniprot Id
    10188 Entrez Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME
    Uniprot Status Swiss-Prot
    Interpro Acc IPR001245

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

  • RussLampel: ENSG00000061938

    • Version: 26-July-2011

    Alternate Names:
    TNK2 Display Id
    ACTIVATED CDC42 KINASE 1 (EC 2.7.1.112) (ACK-1) (TYROSINE KINASE NON- RECEPTOR PROTEIN 2). [SOURCE:UNIPROT/SWISSPROT;ACC:Q07912] Description
    ENSG00000061938 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HingoraniCasas: ENSG00000061938

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000061938 Gene Symbol
    TNK2 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • GO: TNK2

    • Version: 01-February-2022

    Alternate Names:
    ACK1 GO Gene Synonym

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE, TYROSINE KINASE

    Publications:

  • dGene: TNK2

    • Version: 27-Jun-2013

    Alternate Names:
    10188 Gene ID
    ACK dGene Synonym
    ACK-1 dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, TYROSINE KINASE

    Publications:

  • TTD: Activated CDC42 kinase 1

    • Version: 2020.06.01

    Alternate Names:
    ACK-1 TTD Gene Abbreviation
    T63220 TTD Target ID

    Gene Info:

    Publications:

  • Pharos: TNK2

    • Version: 01-February-2022

    Alternate Names:
    Activated CDC42 kinase 1 Gene Name
    Q07912 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

  • DTC: TNK2

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications: