7166 |
TRYPTOPHAN HYDROXYLASE 1 |
TPH1 |
TPRH |
TRPH |
191060 |
12008 |
ENSG00000129167 |
OTTHUMG00000166421 |
P17752 |
TPH1_HUMAN |
PA355 |
TRYPTOPHAN 5-HYDROXYLASE 1 |
Tryptophan 5-monooxygenase 1 |
TPH |
TRYPTOPHAN 5-HYDROXYLASE 1 (EC 1.14.16.4) (TRYPTOPHAN 5-MONOOXYGENASE 1). [SOURCE:UNIPROT/SWISSPROT;ACC:P17752] |
Tryptophan 5-hydroxylase |
T45083 |
Tryptophan hydroxylase |
T51593 |
T78915 |
Target Subclass | 1.14.16.4 |
Target Main Class | Enzymes |
Uniprot Status | Swiss-Prot |
Interpro Type | Family |
Interpro Short Name | ArAA_hydroxylase |
Uniprot Evidence | 1: Evidence at protein level |
Interpro Acc | IPR001273 |
Interpro Name | Aromatic amino acid hydroxylase |
Human Readable Name | DRUGGABLE GENOME |
Target Class | Enzymes |
Target Subclass | EC:1.14.16.4 |
Gene Biotype | PROTEIN_CODING |
DRUGGABLE GENOME |
inhibitor (inhibitory) |
Novel drug target | Established target |
Trial Name | LX1032 |
Mechanism of Interaction | Tryptophan 5-hydroxylase inhibitor |
n/a |
Trial Name | Sapropterin |
Novel drug target | Established target |
antagonist (inhibitory) |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Tryptophan 5-hydroxylase inhibitor |
TPH1 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
TPH1 | Gene Symbol |
Target Class | Enzymes |
Target Subclass | EC:1.14.16.4 |
P17752 | Uniprot Accession |
TPH1 | Gene Symbol |
ENSG00000129167 | Ensembl Gene Id |
Target Subclass | 1.14.16.4 |
Target Main Class | Enzymes |
TPH1 | Uniprot Gene Name |
TRYPTOPHAN 5-HYDROXYLASE 1 | Uniprot Protein Name |
ENSG00000129167 | Ensembl Gene Id |
Uniprot Status | Swiss-Prot |
Interpro Type | Family |
Interpro Short Name | ArAA_hydroxylase |
DRUGGABLE GENOME |
TPH1 | Display Id |
TRYPTOPHAN 5-HYDROXYLASE 1 (EC 1.14.16.4) (TRYPTOPHAN 5-MONOOXYGENASE 1). [SOURCE:UNIPROT/SWISSPROT;ACC:P17752] | Description |
ENSG00000129167 | Ensembl Gene Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
PA355 | PharmGKB ID |
ENSG00000129167 | Gene Symbol |
TPH1 | Ensembl Id |
DRUGGABLE GENOME |
TPRH | GENE_SYMBOL |
TRPH | GENE_SYMBOL |
TPH1 | GENE_SYMBOL |
TPH | TTD Gene Abbreviation |
T45083 | TTD Target ID |
TPH1 | TTD Gene Abbreviation |
T78915 | TTD Target ID |
TPH | TTD Gene Abbreviation |
T51593 | TTD Target ID |