DGIdb - TRPV1 Gene Record

TRPV1 7442 Druggable Genome

Alternate Names:

7442
TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 1
TRPV1
VR1
602076
12716
ENSG00000196689
OTTHUMG00000177649
Osm-9-like TRP channel 1
Capsaicin receptor
Vanilloid receptor 1
OTRPC1
Q8NER1
TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 1 (TRPV1) (OSM-9-LIKE TRP CHANNEL 1) (OTRPC1) (VANILLOID RECEPTOR 1) (CAPSAICIN RECEPTOR). [SOURCE:UNIPROT/SWISSPROT;ACC:Q8NER1]
PA37329
Transient receptor potential cation channel V1
T83193

Gene Info:

Initial Gene Query	TRPV1
Counted Citations from 1950-2000	2202
Human Readable Name	DRUGGABLE GENOME
Target Subclass	TC:1.A.4
Target Class	Transporters
Gene Biotype	PROTEIN_CODING

(8 More Sources)

Gene Categories: Category Details

KINASE
ION CHANNEL
EXTERNAL SIDE OF PLASMA MEMBRANE
DRUGGABLE GENOME

Publications:

Terada Y et al., 2014, Activation and inhibition of thermosensitive TRP channels by voacangine, an alkaloid present in Voacanga africana, an African tree., J Nat Prod
Seephonkai P et al., 2011, Ferruginenes A-C from Rhododendron ferrugineum and their cytotoxic evaluation., J Nat Prod
Dasari R et al., 2015, Wittig derivatization of sesquiterpenoid polygodial leads to cytostatic agents with activity against drug resistant cancer cells and capable of pyrrolylation of primary amines., Eur J Med Chem
Ortar G et al., 2013, Tetrahydro-β-carboline derivatives targeting fatty acid amide hydrolase (FAAH) and transient receptor potential (TRP) channels., Bioorg Med Chem Lett
Pickering G et al., 2020, Paracetamol and Pain Modulation by TRPV1, UGT2B15, SULT1A1 Genotypes: A Randomized Clinical Trial in Healthy Volunteers., Pain Med
Mallet et al., 2010, TRPV1 in brain is involved in acetaminophen-induced antinociception., PLoS ONE
Högestätt et al., 2005, Conversion of acetaminophen to the bioactive N-acylphenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous system., J. Biol. Chem.
Nishihara K et al., 2002, Sensitizing effects of lafutidine on CGRP-containing afferent nerves in the rat stomach., Br J Pharmacol
Szallasi A et al., 1990, Resiniferatoxin and its analogs provide novel insights into the pharmacology of the vanilloid (capsaicin) receptor., Life Sci
Szallasi A et al., 1993, Characterization of a peripheral vanilloid (capsaicin) receptor in the urinary bladder of the rat., Life Sci
Terada Y et al., 2015, Structure-Activity Relationship Study on Isothiocyanates: Comparison of TRPA1-Activating Ability between Allyl Isothiocyanate and Specific Flavor Components of Wasabi, Horseradish, and White Mustard., J Nat Prod
Wallace et al., 2011, Qutenza®: a capsaicin 8% patch for the management of postherpetic neuralgia., Expert Rev Neurother
Anand et al., 2011, Topical capsaicin for pain management: therapeutic potential and mechanisms of action of the new high-concentration capsaicin 8% patch., Br J Anaesth
Hirota et al., 2003, The effects of local and intravenous anesthetics on recombinant rat VR1 vanilloid receptors., Anesth. Analg.
Lee et al., 2006, A role for vanilloid receptor 1 (TRPV1) and endocannabinnoid signalling in the regulation of spontaneous and L-DOPA induced locomotion in normal and reserpine-treated rats., Neuropharmacology
Stein et al., 2006, Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane., J. Gen. Physiol.
Yang F et al., 2015, Structural mechanism underlying capsaicin binding and activation of the TRPV1 ion channel., Nat Chem Biol
Smutzer G et al., 2016, Integrating TRPV1 Receptor Function with Capsaicin Psychophysics., Adv Pharmacol Sci
Szabó et al., 2005, Role of transient receptor potential vanilloid 1 receptors in adjuvant-induced chronic arthritis: in vivo study using gene-deficient mice., J. Pharmacol. Exp. Ther.
Pabbidi et al., 2008, Direct role of streptozotocin in inducing thermal hyperalgesia by enhanced expression of transient receptor potential vanilloid 1 in sensory neurons., Mol. Pharmacol.
Lin Z et al., 2011, Nobilamides A-H, long-acting transient receptor potential vanilloid-1 (TRPV1) antagonists from mollusk-associated bacteria., J Med Chem
Burgess G et al., 2010, The discovery and development of analgesics: new mechanisms, new modalities., J Clin Invest

RESINIFERATOXIN TRPV1

Interaction Score: 4.18

Interaction Types & Directionality:

activator (activating)

Interaction Info:

Trial Name resiniferatoxin, RTX

Novel drug target Established target

PMIDs:
11906962 2174484 8483387

Sources:
TdgClinicalTrial TTD
NOBILAMIDE B TRPV1

Interaction Score: 3.34

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21524089

Sources:
DTC
PHE377 TRPV1

Interaction Score: 3.34

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Mechanism of Interaction Vanilloid receptor antagonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD
XEN-D0501 TRPV1

Interaction Score: 3.34

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Mechanism of Interaction Vanilloid receptor antagonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD
ABT-102 TRPV1

Interaction Score: 3.34

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Mechanism of Interaction Vanilloid receptor antagonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD
MAVATREP TRPV1

Interaction Score: 3.34

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Vanilloid receptor antagonist

PMIDs:
None found

Sources:
ChemblInteractions TTD
DWP05195 TRPV1

Interaction Score: 3.34

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Mechanism of Interaction Vanilloid receptor antagonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD
NGD-8243 TRPV1

Interaction Score: 3.34

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Vanilloid receptor antagonist

Trial Name NGD-8243, MK-2295

PMIDs:
None found

Sources:
TdgClinicalTrial ChemblInteractions
MR-1817 TRPV1

Interaction Score: 3.34

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Vanilloid receptor antagonist

PMIDs:
None found

Sources:
ChemblInteractions TTD
CHEMBL191534 TRPV1

Interaction Score: 3.34

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23206861

Sources:
DTC
POLYGODIAL TRPV1

Interaction Score: 3.34

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
26360047

Sources:
DTC
FERRUGINENE B TRPV1

Interaction Score: 3.34

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21443171

Sources:
DTC
PAC-14028 TRPV1

Interaction Score: 3.34

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Mechanism of Interaction Vanilloid receptor antagonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD
GRC-15300 TRPV1

Interaction Score: 1.67

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21041957

Sources:
TTD
SAF312 TRPV1

Interaction Score: 1.67

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction Vanilloid receptor inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
VOACANGINE TRPV1

Interaction Score: 1.67

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
24484240

Sources:
DTC
ISOPROPYL ISOTHIOCYANATE TRPV1

Interaction Score: 1.67

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
26263397

Sources:
DTC
CHEMBL104028 TRPV1

Interaction Score: 1.67

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD
SYL-1001 TRPV1

Interaction Score: 1.67

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Mechanism of Interaction Vanilloid receptor antagonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
GRC-6211 TRPV1

Interaction Score: 1.67

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Mechanism of Interaction Vanilloid receptor antagonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD
AMG-517 TRPV1

Interaction Score: 1.67

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Mechanism of Interaction Vanilloid receptor antagonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
JTS-653 TRPV1

Interaction Score: 1.67

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Mechanism of Interaction Vanilloid receptor antagonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
AZD1386 TRPV1

Interaction Score: 1.67

Interaction Types & Directionality:

antagonist (inhibitory)

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction Vanilloid receptor antagonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
SB-705498 TRPV1

Interaction Score: 1.67

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Vanilloid receptor antagonist

PMIDs:
None found

Sources:
ChemblInteractions
ALLYL ISOTHIOCYANATE TRPV1

Interaction Score: 1.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
26263397

Sources:
DTC
ZUCAPSAICIN TRPV1

Interaction Score: 0.84

Interaction Types & Directionality:

activator (activating)

agonist (activating)

Interaction Info:

Trial Name zucapsaicin, civamide, WL-1002,,Civanex

Novel drug target Established target

PMIDs:
26053297 26884754

Sources:
TdgClinicalTrial
CAPSAICIN TRPV1

Interaction Score: 0.67

Interaction Types & Directionality:

activator (activating)

agonist (activating)

Interaction Info:

Trial Name Adlea

Novel drug target Established target

Trial Name Transacin

PMIDs:
21158551 21852280

Sources:
DTC TdgClinicalTrial ChemblInteractions TTD
BENZYL ISOTHIOCYANATE TRPV1

Interaction Score: 0.56

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
26263397

Sources:
DTC
PHENETHYLISOTHIOCYANATE TRPV1

Interaction Score: 0.42

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
26263397

Sources:
DTC
ACETAMINOPHEN TRPV1

Interaction Score: 0.21

Interaction Types & Directionality:

activator (activating)

Interaction Info:

Mechanism of Interaction Vanilloid receptor opener

Direct Interaction yes

PMIDs:
30908574 20862299 15987694

Sources:
ChemblInteractions PharmGKB
CAPSAZEPINE TRPV1

Interaction Score: 0.16

Interaction Types & Directionality:

blocker (inhibitory)

Interaction Info:

PMIDs:
24484240

Sources:
DTC
RESERPINE TRPV1

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16806299

Sources:
NCI
WORTMANNIN TRPV1

Interaction Score: 0.12

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17074976

Sources:
NCI
PROPOFOL TRPV1

Interaction Score: 0.12

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12760991

Sources:
NCI
INDOMETHACIN TRPV1

Interaction Score: 0.1

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15831443

Sources:
NCI
LEVODOPA TRPV1

Interaction Score: 0.09

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16806299

Sources:
NCI
STREPTOZOCIN TRPV1

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
18089839

Sources:
NCI

Ensembl: ENSG00000196689
- Version: 101_38
Alternate Names:

TRPV1 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
TdgClinicalTrial: Q8NER1
- Version: January-2014
Alternate Names:

TRPV1 Gene Symbol

Gene Info:

Target Subclass TC:1.A.4

Target Class Transporters

Publications:

RussLampel: ENSG00000196689

Version: 26-July-2011

Alternate Names:

TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 1 (TRPV1) (OSM-9-LIKE TRP CHANNEL 1) (OTRPC1) (VANILLOID RECEPTOR 1) (CAPSAICIN RECEPTOR). [SOURCE:UNIPROT/SWISSPROT;ACC:Q8NER1] Description

TRPV1 Display Id

ENSG00000196689 Ensembl Gene Id

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:

BaderLabGenes: TRPV1
- Version: February-2014
Alternate Names:

7442 Entrez Gene ID

Gene Info:

Initial Gene Query TRPV1

Counted Citations from 1950-2000 2202

Gene Categories:

ION CHANNEL

Publications:
PharmGKB: TRPV1
- Version: 18-August-2020
Alternate Names:

PA37329 PharmGKB ID

Gene Info:

Publications:

Pickering G et al., 2020, Paracetamol and Pain Modulation by TRPV1, UGT2B15, SULT1A1 Genotypes: A Randomized Clinical Trial in Healthy Volunteers., Pain Med
TTD: Transient receptor potential cation channel V1
- Version: 2020.06.01
Alternate Names:

TRPV1 TTD Gene Abbreviation

T83193 TTD Target ID

Gene Info:

Publications:

Burgess G et al., 2010, The discovery and development of analgesics: new mechanisms, new modalities., J Clin Invest

NCI: TRPV1

Version: 14-September-2017

Alternate Names:

Gene Info:

Publications:

Christoph et al., 2007, Antinociceptive effect of antisense oligonucleotides against the vanilloid receptor VR1/TRPV1., Neurochem. Int.

Szabó et al., 2005, Role of transient receptor potential vanilloid 1 receptors in adjuvant-induced chronic arthritis: in vivo study using gene-deficient mice., J. Pharmacol. Exp. Ther.

Hirota et al., 2003, The effects of local and intravenous anesthetics on recombinant rat VR1 vanilloid receptors., Anesth. Analg.

DTC: TRPV1

Version: 02-September-2020

Alternate Names:

Gene Info:

Publications:

Dasari R et al., 2015, Wittig derivatization of sesquiterpenoid polygodial leads to cytostatic agents with activity against drug resistant cancer cells and capable of pyrrolylation of primary amines., Eur J Med Chem

Terada Y et al., 2014, Activation and inhibition of thermosensitive TRP channels by voacangine, an alkaloid present in Voacanga africana, an African tree., J Nat Prod

Terada Y et al., 2015, Structure-Activity Relationship Study on Isothiocyanates: Comparison of TRPA1-Activating Ability between Allyl Isothiocyanate and Specific Flavor Components of Wasabi, Horseradish, and White Mustard., J Nat Prod

ChemblInteractions: VR1
- Version: chembl_23
Alternate Names:

VR1 GENE_SYMBOL

TRPV1 GENE_SYMBOL

Transient receptor potential cation channel subfamily V member 1 UNIPROT

Gene Info:

Publications:
HingoraniCasas: ENSG00000196689
- Version: 31-May-2017
Alternate Names:

ENSG00000196689 Gene Symbol

TRPV1 Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
GO: TRPV1
- Version: 01-February-2022
Alternate Names:

VR1 GO Gene Synonym

Gene Info:

Gene Categories:

ION CHANNEL, EXTERNAL SIDE OF PLASMA MEMBRANE

Publications:
Pharos: TRPV1
- Version: 01-February-2022
Alternate Names:

Transient receptor potential cation channel subfamily V member 1 Gene Name

Q8NER1 UniProt ID

Gene Info:

Gene Categories:

KINASE, ION CHANNEL

Publications:

Trial Name	resiniferatoxin, RTX
Novel drug target	Established target

Mechanism of Interaction	Vanilloid receptor antagonist
Direct Interaction	yes

Mechanism of Interaction	Vanilloid receptor inhibitor
Direct Interaction	yes

Trial Name	zucapsaicin, civamide, WL-1002,,Civanex
Novel drug target	Established target

Trial Name	Adlea
Novel drug target	Established target
Trial Name	Transacin

Mechanism of Interaction	Vanilloid receptor opener
Direct Interaction	yes

TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 1 (TRPV1) (OSM-9-LIKE TRP CHANNEL 1) (OTRPC1) (VANILLOID RECEPTOR 1) (CAPSAICIN RECEPTOR). [SOURCE:UNIPROT/SWISSPROT;ACC:Q8NER1]	Description
TRPV1	Display Id
ENSG00000196689	Ensembl Gene Id

VR1	GENE_SYMBOL
TRPV1	GENE_SYMBOL
Transient receptor potential cation channel subfamily V member 1	UNIPROT

Transient receptor potential cation channel subfamily V member 1	Gene Name
Q8NER1	UniProt ID

TRPV1 Gene Record

TRPV1 7442 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

Interaction Types & Directionality: activator (activating)

Interaction Info: Trial Name resiniferatoxin, RTX Novel drug target Established target

PMIDs: 11906962 2174484 8483387

Sources: TdgClinicalTrial TTD

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21524089

Sources: DTC

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Mechanism of Interaction Vanilloid receptor antagonist Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions TTD

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Mechanism of Interaction Vanilloid receptor antagonist Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions TTD

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Mechanism of Interaction Vanilloid receptor antagonist Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions TTD

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Direct Interaction yes Mechanism of Interaction Vanilloid receptor antagonist

PMIDs: None found

Sources: ChemblInteractions TTD

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Mechanism of Interaction Vanilloid receptor antagonist Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions TTD

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Direct Interaction yes Mechanism of Interaction Vanilloid receptor antagonist Trial Name NGD-8243, MK-2295

PMIDs: None found

Sources: TdgClinicalTrial ChemblInteractions

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Direct Interaction yes Mechanism of Interaction Vanilloid receptor antagonist

PMIDs: None found

Sources: ChemblInteractions TTD

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 23206861

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 26360047

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21443171

Sources: DTC

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Mechanism of Interaction Vanilloid receptor antagonist Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions TTD

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21041957

Sources: TTD

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction Vanilloid receptor inhibitor Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 24484240

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 26263397

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: TTD

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Mechanism of Interaction Vanilloid receptor antagonist Direct Interaction yes

Interaction Types & Directionality:

activator (activating)

Interaction Info:

Trial Name resiniferatoxin, RTX

Novel drug target Established target

PMIDs:
11906962 2174484 8483387

Sources:
TdgClinicalTrial TTD

Interaction Types & Directionality:

n/a

PMIDs:
21524089

Sources:
DTC

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Mechanism of Interaction Vanilloid receptor antagonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Mechanism of Interaction Vanilloid receptor antagonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Mechanism of Interaction Vanilloid receptor antagonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Vanilloid receptor antagonist

PMIDs:
None found

Sources:
ChemblInteractions TTD

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Mechanism of Interaction Vanilloid receptor antagonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Vanilloid receptor antagonist

Trial Name NGD-8243, MK-2295

PMIDs:
None found

Sources:
TdgClinicalTrial ChemblInteractions

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Vanilloid receptor antagonist

PMIDs:
None found

Sources:
ChemblInteractions TTD

Interaction Types & Directionality:

n/a

PMIDs:
23206861

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
26360047

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
21443171

Sources:
DTC

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Mechanism of Interaction Vanilloid receptor antagonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD

Interaction Types & Directionality:

n/a

PMIDs:
21041957

Sources:
TTD

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction Vanilloid receptor inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

n/a

PMIDs:
24484240

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
26263397

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
TTD

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Mechanism of Interaction Vanilloid receptor antagonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Mechanism of Interaction Vanilloid receptor antagonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Mechanism of Interaction Vanilloid receptor antagonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Mechanism of Interaction Vanilloid receptor antagonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions