7277 |
TUBULIN ALPHA 4A |
TUBA4A |
ALS22 |
H2-ALPHA |
TUBA1 |
191110 |
12407 |
ENSG00000127824 |
OTTHUMG00000133126 |
Testis-specific alpha-tubulin |
Tubulin alpha-1 chain |
Tubulin H2-alpha |
Alpha-tubulin 1 |
Tubulin alpha-4A chain |
P68366 |
TBA4A_HUMAN |
TUBULIN ALPHA-1 CHAIN (ALPHA-TUBULIN 1) (TESTIS-SPECIFIC ALPHA- TUBULIN) (TUBULIN H2-ALPHA). [SOURCE:UNIPROT/SWISSPROT;ACC:P68366] |
TBA1_HUMAN |
Target Class | Miscellaneous |
Target Subclass | StructuralAndAdhesion |
Target Subclass | Cytoskeleton |
Interpro Short Name | Tubulin |
Human Readable Name | DRUGGABLE GENOME |
Interpro Type | Family |
Interpro Name | Tubulin |
Uniprot Evidence | 1: Evidence at protein level |
Interpro Acc | IPR000217 |
Uniprot Status | Swiss-Prot |
Gene Biotype | PROTEIN_CODING |
DRUGGABLE GENOME |
binder |
inhibitor (inhibitory) |
Trial Name | cabazitaxel, XRP6258,Jevtana |
Novel drug target | Established target |
Mechanism of Interaction | Tubulin inhibitor |
n/a |
Direct Interaction | yes |
Mechanism of Interaction | Tubulin stabiliser |
inhibitor (inhibitory) |
Mechanism of Interaction | Tubulin inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Tubulin inhibitor |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | Tubulin disrupting agent |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Tubulin inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Tubulin inhibitor |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | Tubulin disrupting agent |
Direct Interaction | yes |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Tubulin inhibitor |
n/a |
Mechanism of Interaction | Tubulin stabiliser |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Tubulin inhibitor |
Direct Interaction | yes |
n/a |
Direct Interaction | yes |
Mechanism of Interaction | Tubulin stabiliser |
inhibitor (inhibitory) |
Mechanism of Interaction | Tubulin inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Tubulin inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Tubulin inhibitor |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Tubulin inhibitor |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Tubulin inhibitor |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Tubulin inhibitor |
inhibitor (inhibitory) |
Mechanism of Interaction | Tubulin inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Tubulin inhibitor |
Direct Interaction | yes |
TUBA4A | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
TBA1_HUMAN | Display Id |
ENSG00000127824 | Ensembl Gene Id |
TUBULIN ALPHA-1 CHAIN (ALPHA-TUBULIN 1) (TESTIS-SPECIFIC ALPHA- TUBULIN) (TUBULIN H2-ALPHA). [SOURCE:UNIPROT/SWISSPROT;ACC:P68366] | Description |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
TUBA4A | Gene Symbol |
Target Class | Miscellaneous |
Target Subclass | StructuralAndAdhesion |
Target Subclass | Cytoskeleton |
P68366 | Uniprot Accession |
ENSG00000127824 | Ensembl Gene Id |
TBA4A_HUMAN | Uniprot Id |
Interpro Type | Family |
Human Readable Name | DRUGGABLE GENOME |
Interpro Name | Tubulin |
DRUGGABLE GENOME |
Tubulin alpha-1 chain | UNIPROT |
TUBA1 | GENE_SYMBOL |
TUBA4A | GENE_SYMBOL |
ENSG00000127824 | Gene Symbol |
TUBA4A | Ensembl Id |
DRUGGABLE GENOME |