DGIdb - VDR Gene Record

VDR 7421 Druggable Genome

Alternate Names:

7421
VITAMIN D RECEPTOR
VDR
NR1I1
PPP1R163
601769
12679
ENSG00000111424
OTTHUMG00000169890
P11473
VDR_HUMAN
PA37301
Vitamin D3 receptor
1,25-dihydroxyvitamin D3 receptor
Nuclear receptor subfamily 1 group I member 1
VITAMIN D3 RECEPTOR (VDR) (1,25-DIHYDROXYVITAMIN D3 RECEPTOR). [SOURCE:UNIPROT/SWISSPROT;ACC:P11473]
T34234

Gene Info:

Target Main Class	Receptors
Target Subclass	Nuclear receptor
Uniprot Evidence	1: Evidence at protein level
Human Readable Name	DRUGGABLE GENOME
Interpro Acc	IPR000536
Interpro Type	Domain
Human Readable Name	NUCLEAR HORMONE RECEPTOR
Interpro Name	Nuclear hormone receptor, ligand-binding, core
Uniprot Status	Swiss-Prot
Interpro Short Name	Nucl_hrmn_rcpt_lig-bd_core
Initial Gene Query	NR1I1
Counted Citations from 1950-2000	2939
Target Class	Receptors
Gene Biotype	PROTEIN_CODING

(11 More Sources)

Gene Categories: Category Details

NUCLEAR HORMONE RECEPTOR
DRUGGABLE GENOME
TRANSCRIPTION FACTOR

Publications:

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
Carvallo et al., 2007, The 1alpha,25-dihydroxy Vitamin D3 receptor preferentially recruits the coactivator SRC-1 during up-regulation of the osteocalcin gene., J. Steroid Biochem. Mol. Biol.
Ewing et al., 2007, Novel regulatory role for human Acf1 in transcriptional repression of vitamin D3 receptor-regulated genes., Mol. Endocrinol.
Liu et al., 2006, Expression of vitamin D3 receptor in kidney tumors., Hum. Pathol.
Straube et al., 2010, Vitamin D for the treatment of chronic painful conditions in adults., Cochrane Database Syst Rev
Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
Jurutka et al., 2007, Vitamin D receptor: key roles in bone mineral pathophysiology, molecular mechanism of action, and novel nutritional ligands., J. Bone Miner. Res.
Mikhak et al., 2007, Vitamin D receptor (VDR) gene polymorphisms and haplotypes, interactions with plasma 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D, and prostate cancer risk., Prostate
Marks et al., 2007, Transgenic expression of the human Vitamin D receptor (hVDR) in the duodenum of VDR-null mice attenuates the age-dependent decline in calcium absorption., J. Steroid Biochem. Mol. Biol.
Gallagher et al., 2010, Vitamin D insufficiency, deficiency, and bone health., J. Clin. Endocrinol. Metab.
Reinhart, 2004, Vitamin D analogs: novel therapeutic agents for cardiovascular disease?, Curr Opin Investig Drugs
Leman et al., 2003, Regulation of androgen and vitamin d receptors by 1,25-dihydroxyvitamin D3 in human prostate epithelial and stromal cells., J. Urol.
Andress, Vitamin D treatment in chronic kidney disease., Semin Dial
Wu-Wong et al., 2010, Comparison of the pharmacological effects of paricalcitol and doxercalciferol on the factors involved in mineral homeostasis., Int J Endocrinol
Brancaccio et al., 2009, New acquisitions in therapy of secondary hyperparathyroidism in chronic kidney disease and peritoneal dialysis patients: role of vitamin D receptor activators., Contrib Nephrol
Ames SK et al., 1999, Vitamin D receptor gene Fok1 polymorphism predicts calcium absorption and bone mineral density in children., J Bone Miner Res
Yamamoto H et al., 1999, The caudal-related homeodomain protein Cdx-2 regulates vitamin D receptor gene expression in the small intestine., J Bone Miner Res
Haussler MR et al., 1977, Basic and clinical concepts related to vitamin D metabolism and action (first of two parts)., N Engl J Med
Creatsa M et al., 2011, The effect of vitamin D receptor BsmI genotype on the response to osteoporosis treatment in postmenopausal women: a pilot study., J Obstet Gynaecol Res
Senel E et al., 2011, Painful purple plaques on the thighs of an immunosuppressed patient., Clin Exp Dermatol
Elnenaei MO et al., 2011, Genomic and metabolomic patterns segregate with responses to calcium and vitamin D supplementation., Br J Nutr
Ryan C et al., 2010, Clinical and genetic predictors of response to narrowband ultraviolet B for the treatment of chronic plaque psoriasis., Br J Dermatol
Lambrinoudaki I et al., 2011, BsmI vitamin D receptor's polymorphism and bone mineral density in men and premenopausal women on long-term antiepileptic therapy., Eur J Neurol
Arabi A et al., 2009, Vitamin D receptor gene polymorphisms modulate the skeletal response to vitamin D supplementation in healthy girls., Bone
Jehan F et al., 2008, Vitamin D receptor genotype in hypophosphatemic rickets as a predictor of growth and response to treatment., J Clin Endocrinol Metab
Hubner RA et al., 2008, Dairy products, polymorphisms in the vitamin D receptor gene and colorectal adenoma recurrence., Int J Cancer
Dayangac-Erden D et al., 2007, Polymorphisms of vitamin D receptor gene in Turkish familial psoriasis patients., Arch Dermatol Res
van Etten E et al., 2007, The vitamin D receptor gene FokI polymorphism: functional impact on the immune system., Eur J Immunol
d'Alésio A et al., 2005, Two single-nucleotide polymorphisms in the human vitamin D receptor promoter change protein-DNA complex formation and are associated with height and vitamin D status in adolescent girls., Hum Mol Genet
Abrams SA et al., 2005, Vitamin D receptor Fok1 polymorphisms affect calcium absorption, kinetics, and bone mineralization rates during puberty., J Bone Miner Res
Halsall JA et al., 2005, Vitamin D receptor gene polymorphisms, particularly the novel A-1012G promoter polymorphism, are associated with vitamin D3 responsiveness and non-familial susceptibility in psoriasis., Pharmacogenet Genomics
Morrison NA et al., 2005, Vitamin D receptor genotypes influence the success of calcitriol therapy for recurrent vertebral fracture in osteoporosis., Pharmacogenet Genomics
Palomba S et al., 2005, BsmI vitamin D receptor genotypes influence the efficacy of antiresorptive treatments in postmenopausal osteoporotic women. A 1-year multicenter, randomized and controlled trial., Osteoporos Int
Roth DE et al., 2004, Association between vitamin D receptor gene polymorphisms and response to treatment of pulmonary tuberculosis., J Infect Dis
International HapMap Consortium., 2003, The International HapMap Project., Nature
Arai H et al., 2001, The polymorphism in the caudal-related homeodomain protein Cdx-2 binding element in the human vitamin D receptor gene., J Bone Miner Res
Jurutka PW et al., 2000, The polymorphic N terminus in human vitamin D receptor isoforms influences transcriptional activity by modulating interaction with transcription factor IIB., Mol Endocrinol
Glorieux et al., 2001, The anti-proliferative effect of calcitriol on HL-60 cells is neutralized by uraemic biological fluids., Nephrol. Dial. Transplant.
Belorusova AY et al., 2014, Structural insights into the molecular mechanism of vitamin D receptor activation by lithocholic acid involving a new mode of ligand recognition., J Med Chem
Laverny G et al., 2009, Synthesis and anti-inflammatory properties of 1alpha,25-dihydroxy-16-ene-20-cyclopropyl-24-oxo-vitamin D3, a hypocalcemic, stable metabolite of 1alpha,25-dihydroxy-16-ene-20-cyclopropyl-vitamin D3., J Med Chem
Wongmayura A et al., 2012, Novel vitamin D receptor ligands bearing a spherical hydrophobic core structure--comparison of bicyclic hydrocarbon derivatives with boron cluster derivatives., Bioorg Med Chem Lett
Lamblin M et al., 2010, An o-aminoanilide analogue of 1α,25-dihydroxyvitamin D(3) functions as a strong vitamin D receptor antagonist., J Med Chem
Lamblin M et al., 2010, Vitamin D receptor agonist/histone deacetylase inhibitor molecular hybrids., Bioorg Med Chem
Allegra S et al., 2019, The effect of vitamin D pathway genes and deferasirox pharmacogenetics on liver iron in thalassaemia major patients., Pharmacogenomics J
Gilad et al., 2005, Regulation of vitamin D receptor expression via estrogen-induced activation of the ERK 1/2 signaling pathway in colon and breast cancer cells., J. Endocrinol.
Desai et al., 1995, Control of 1,25-dihydroxyvitamin D3 receptor-mediated enhancement of osteocalcin gene transcription: effects of perturbing phosphorylation pathways by okadaic acid and staurosporine., Endocrinology
Batie S et al., 2013, Synthesis and biological evaluation of halogenated curcumin analogs as potential nuclear receptor selective agonists., Bioorg Med Chem
Bartik L et al., 2010, Curcumin: a novel nutritionally derived ligand of the vitamin D receptor with implications for colon cancer chemoprevention., J Nutr Biochem
Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
Murthy et al., 2005, Androgen receptor signaling and vitamin D receptor action in prostate cancer cells., Prostate
Fujishima et al., 2010, Novel vitamin D receptor ligands having a carboxyl group as an anchor to arginine 274 in the ligand-binding domain., J. Steroid Biochem. Mol. Biol.
Ritter et al., 2011, Direct suppression of Pth gene expression by the vitamin D prohormones doxercalciferol and calcidiol requires the vitamin D receptor., J. Mol. Endocrinol.
Grenet et al., 2000, Evidence for the impairment of the vitamin D activation pathway by cyclosporine A., Biochem. Pharmacol.
Shahabi P et al., 2019, Nuclear receptor gene polymorphisms and warfarin dose requirements in the Quebec Warfarin Cohort., Pharmacogenomics J
Reinhardt et al., 1989, Ketoconazole inhibits self-induced metabolism of 1,25-dihydroxyvitamin D3 and amplifies 1,25-dihydroxyvitamin D3 receptor up-regulation in rat osteosarcoma cells., Arch. Biochem. Biophys.
Cusato J et al., 2016, Vitamin D pathway gene polymorphisms as predictors of hepatitis C virus-related mixed cryoglobulinemia., Pharmacogenet Genomics
Cusato J et al., 2015, VDR gene polymorphisms impact on anemia at 2 weeks of anti-HCV therapy: a possible mechanism for early RBV-induced anemia., Pharmacogenet Genomics
Qaw et al., 1992, Metabolism of 25-hydroxydihydrotachysterol3 in bone cells in vitro., Steroids
Qaw et al., 1993, In vivo metabolism of the vitamin D analog, dihydrotachysterol. Evidence for formation of 1 alpha,25- and 1 beta,25-dihydroxy-dihydrotachysterol metabolites and studies of their biological activity., J. Biol. Chem.
Cusato J et al., 2015, Intracellular accumulation of boceprevir according to plasma concentrations and pharmacogenetics., Int J Antimicrob Agents
Mossetti G et al., 2008, Vitamin D receptor gene polymorphisms predict acquired resistance to clodronate treatment in patients with Paget's disease of bone., Calcif Tissue Int
Otrock ZK et al., 2008, Vitamin D receptor genotypes and response to zoledronic acid therapy in thalassemia-induced osteoporosis., Ann Hematol
Palomba et al., 2003, Effectiveness of alendronate treatment in postmenopausal women with osteoporosis: relationship with BsmI vitamin D receptor genotypes., Clin. Endocrinol. (Oxf)
Tofteng CL et al., 2002, Two polymorphisms in the vitamin D receptor gene--association with bone mass and 5-year change in bone mass with or without hormone-replacement therapy in postmenopausal women: the Danish Osteoporosis Prevention Study., J Bone Miner Res
Marc J et al., 1999, VDR genotype and response to etidronate therapy in late postmenopausal women., Osteoporos Int
Deng HW et al., 1998, Change of bone mass in postmenopausal Caucasian women with and without hormone replacement therapy is associated with vitamin D receptor and estrogen receptor genotypes., Hum Genet
Lee et al., 1991, Effect of glucocorticoids and 1,25-dihydroxyvitamin D3 on the developmental expression of the rat intestinal vitamin D receptor gene., Endocrinology
Guerrero et al., 2004, Hydrocortisone and deflazacort induce different effects on vitamin D receptor level increase produced by 1,25-dihydroxyvitamin D3 in rat osteoblast-like UMR-106 cells., J. Rheumatol.
Adorini L et al., 2007, Inhibition of prostate growth and inflammation by the vitamin D receptor agonist BXL-628 (elocalcitol)., J Steroid Biochem Mol Biol
Leman et al., 2003, Effects of 1,25-dihydroxyvitamin D3 on the distribution of androgen and vitamin D receptors in human prostate neonatal epithelial cells., J. Cell. Biochem.
Jakob et al., 1994, Topoisomerase I-inhibition enhances vitamin D-responsive expression of the receptor for lipopolysaccharide binding protein CD 14., Biochem. Biophys. Res. Commun.
Liel et al., 1992, Evidence that estrogens modulate activity and increase the number of 1,25-dihydroxyvitamin D receptors in osteoblast-like cells (ROS 17/2.8)., Endocrinology
Rapuri et al., 2001, Caffeine intake increases the rate of bone loss in elderly women and interacts with vitamin D receptor genotypes., Am. J. Clin. Nutr.

CALCIPOTRIOL VDR

Interaction Score: 2.7

Interaction Types & Directionality:

agonist (activating)

antagonist (inhibitory)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
17016423 17139284 11752352 10707958 9933478 21651652 21418277 20716226 20500803 19647104 17763859 17274004 15864137 15861036 15739035 15295697

Sources:
TdgClinicalTrial TEND PharmGKB TTD
CALCIUM VDR

Interaction Score: 1.62

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
19020788 18443790 12608943 12162507 10707958 10692979 9933478 21418277 17274004 15861036 15739035

Sources:
PharmGKB
DIHYDROTACHYSTEROL VDR

Interaction Score: 1.21

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Novel drug target Established target

Trial Name -

PMIDs:
1336906 11752352 8380156 17016423 17139284 20525913

Sources:
TdgClinicalTrial TEND TTD
PARICALCITOL VDR

Interaction Score: 0.67

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Trial Name paricalcitol , Zemplar

Novel drug target Established target

Mechanism of Interaction Vitamin D receptor agonist

PMIDs:
16076355 20204178 11752352 19494617 17016423 17139284

Sources:
TdgClinicalTrial ChemblInteractions TEND TTD
DOXERCALCIFEROL VDR

Interaction Score: 0.54

Interaction Types & Directionality:

agonist (activating)

suppressor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Vitamin D receptor agonist

Trial Name doxercalciferol , Hectorol

PMIDs:
21169421

Sources:
TdgClinicalTrial ChemblInteractions TTD
SEOCALCITOL VDR

Interaction Score: 0.54

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Mechanism of Interaction Vitamin D receptor agonist

Direct Interaction yes

PMIDs:
17016423 17139284

Sources:
ChemblInteractions TTD
CALCITRIOL VDR

Interaction Score: 0.45

Interaction Types & Directionality:

agonist (activating)

antagonist (inhibitory)

Interaction Info:

Trial Name DN-101,Asentar

Novel drug target Established target

Trial Name calcitriol, vitamin D3 derivative,Silkis, Vectical

PMIDs:
10320522 9933478 333287 21651652 21418277 20727239 20716226 20500803 19647104 18827005 18470879 17763859 17274004 16210379 15883634 15864137 15861036 15739035 15295697 14685227 11450701 10707958 11158396 24818857 19309155 22285943 20883026 20452225 15503649 11752352

Sources:
DTC TdgClinicalTrial ChemblInteractions NCI TEND PharmGKB TTD
ERGOCALCIFEROL VDR

Interaction Score: 0.44

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Novel drug target Established target

Trial Name -

Mechanism of Interaction Vitamin D receptor agonist

PMIDs:
17218095 17519354 16949927 20091647 11752352 18290715 17440943 17207992 20525913

Sources:
TdgClinicalTrial ChemblInteractions TEND TTD
ELOCALCITOL VDR

Interaction Score: 0.4

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Mechanism of Interaction Vitamin D receptor agonist

Direct Interaction yes

Trial Name Elocalcitol

PMIDs:
17241782

Sources:
TdgClinicalTrial ChemblInteractions
INECALCITOL VDR

Interaction Score: 0.4

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Trial Name inecalcitol, TX-522

Novel drug target Established target

Mechanism of Interaction Vitamin D receptor agonist

PMIDs:
10592235

Sources:
TdgClinicalTrial ChemblInteractions
BECOCALCIDIOL VDR

Interaction Score: 0.27

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Mechanism of Interaction Vitamin D receptor agonist

Direct Interaction yes

PMIDs:
10592235

Sources:
ChemblInteractions
ILX23-7553 VDR

Interaction Score: 0.27

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Mechanism of Interaction Vitamin D receptor agonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD
CASODEX VDR

Interaction Score: 0.27

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15754350

Sources:
NCI
CHEMBL2112314 VDR

Interaction Score: 0.27

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
20883026

Sources:
DTC
TRICIFEROL VDR

Interaction Score: 0.27

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
20452225

Sources:
DTC
ALENDRONIC ACID VDR

Interaction Score: 0.25

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12608943 19020788 18443790 15739035 12162507 11450701 10692979 9933478 21651652 20500803 18470879 16210379 14685227

Sources:
NCI PharmGKB
CALCIFEDIOL VDR

Interaction Score: 0.2

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

PMIDs:
15503649 11752352

Sources:
TTD
CALCIFEDIOL VDR

Interaction Score: 0.18

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Mechanism of Interaction Vitamin D receptor agonist

Direct Interaction yes

PMIDs:
11752352 15503649

Sources:
ChemblInteractions TTD
FURATHIOCARB VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CAPTAMINE VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CEFONICID VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CALPEPTIN VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DICHLOFENTHION VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DESMOSDUMOTIN C VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
VIOLASTYRENE VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
FENITROTHION VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HERNANDEZINE VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
IPRONIAZID SULFATE VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
MECARBAM VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ANTIAROL VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL54044 VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TETRAHYDROGAMBOGIC ACID VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DIXANTHOGEN VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PROTHIOFOS VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
SULINDAC SULFIDE VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CEFPIROME VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL1179743 VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PHENTHOATE VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TRIAZOPHOS VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
URACIL MUSTARD VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PHYSCION VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL268229 VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
GLIOTOXIN VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL404954 VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL135561 VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHINOMETHIONAT VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ELDECALCITOL VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name eldecalcitol, ED-71

Novel drug target Established target

PMIDs:
None found

Sources:
TdgClinicalTrial
CALPHOSTIN C VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL305695 VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ETHACRIDINE VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
FENBUTATIN OXIDE VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
THIPHENAMIL VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
4'-HYDROXYCHALCONE VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
AZOCYCLOTIN VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DP001 VDR

Interaction Score: 0.13

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Mechanism of Interaction Vitamin D receptor agonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
DALBERGIONE VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
NIFEKALANT VDR

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CLODRONIC ACID VDR

Interaction Score: 0.09

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
19020788 18443790 15739035 12608943 12162507 10692979

Sources:
PharmGKB
CALCIPOTRIENE VDR

Interaction Score: 0.09

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Trial Name calcipotriene + betamethasone dipropionate, LEO-80185,Taclonex, Xamiol

Novel drug target Established target

Mechanism of Interaction Vitamin D receptor agonist

PMIDs:
None found

Sources:
TdgClinicalTrial ChemblInteractions
CHEMBL97858 VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PROSULTIAMINE VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DECYLUBIQUINONE VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
LOFEPRAMINE VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DICLAZURIL VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
FLAVOKAWAIN B VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
METHOXYARACHIDONOYL FLUOROPHOSPHONATE VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ICRF-193 VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
QUINOCIDE VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
MERSALYL VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PHENYLHYDRAZINE VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL164449 VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
1.ALPHA.-HYDROXYVITAMIN D5 VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name MN-201

Novel drug target Established target

PMIDs:
None found

Sources:
TdgClinicalTrial
THYMOL IODIDE VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
IOPHENOXIC ACID VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
4'-METHOXYCHALCONE VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
QUINIZARIN VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
LUNACALCIPOL VDR

Interaction Score: 0.07

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Mechanism of Interaction Vitamin D receptor agonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
CHEMBL521083 VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
SODIUM LAURYL SULFATE VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PEFCALCITOL VDR

Interaction Score: 0.07

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Mechanism of Interaction Vitamin D receptor agonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
CHEMBL180917 VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
LEVISOPRENALINE VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DOCUSATE VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
FPL-55712 VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TINORIDINE VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TOMELUKAST VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL211045 VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CYSTEINE VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
THIOLUTIN VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ICOSAPENT VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL1256719 VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHOLECALCIFEROL VDR

Interaction Score: 0.07

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Vitamin D receptor agonist

PMIDs:
15503649 20435140 11752352

Sources:
DTC ChemblInteractions TTD
TENATOPRAZOLE VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CINTAZONE VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL1256186 VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHINIOFON VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ARACHIDONYL TRIFLUOROMETHYLKETONE VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
MANUMYCIN A VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
VITAMIN K3H2 VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL599712 VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHLORACYZINE VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
FLUACIZINE VDR

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
LINTITRIPT VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL445153 VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ARACHIDONOYL GABA VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ARUNDINE VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHALCONE VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
GANGALEOIDIN VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL462861 VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ANANDAMIDE VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHLORPYRIFOS-METHYL VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CYSTAMINE VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
3,4-DIMETHOXYDALBERGIONE VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ESTROPIPATE VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CEFDITORIN PIVOXIL VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL602763 VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
LAWSONE VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
AMBAZONE VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TEMEFOS VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
BMS-182874 VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
BRONOPOL VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
METHANANDAMIDE VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DIALLYLDISULFIDE VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
4-AMINO-[1,2]NAPHTHOQUINONE VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ZOMEPIRAC SODIUM VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL69367 VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
MECYSTEINE HYDROCHLORIDE VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CLOFENOXYDE VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
MELENGESTROL ACETATE VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL74852 VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CYSTEAMINE HYDROCHLORIDE VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL59150 VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
0-HEXYL-1,3-DIAMINE-PLATINUM 2,2-DICHLORIDE VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
BOCEPREVIR VDR

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
25836019

Sources:
PharmGKB
CHEMBL472940 VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
SAPPANONE A TRIMETHYL ETHER VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
METHYL PARATHIONE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
4,4'-DIMETHOXYDALBERGIONE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PROPICONAZOLE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
IODOFORM VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ALLITRIDIN VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL480626 VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
2',4'-DIHYDROXYCHALCONE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PROROXAN VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ALLOXAN VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TRIBROMSALAN VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
NALED VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL321585 VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
BENZIODARONE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TRIPHENYLSTANNYL ACETATE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DIENOCHLOR VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL601618 VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HALOPROGIN VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ANETHOLTRITHION VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DAMNACANTHAL VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PYRANTEL PAMOATE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CYSTAMINE DIHYDROCHLORIDE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
GARCINOLIC ACID VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DIPHENADIONE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EPALRESTAT VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
REVERSETRIIODOTHYRONINE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL395915 VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
LAVENDUSTIN A VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL59532 VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
MK-571 VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DESERPIDINE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
Z-PRO-PROLINAL VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PHOSALONE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ISOETHARINE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
IDEBENONE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ARACHIDONOYL DOPAMINE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
RALOXIFENE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
19020788 18443790 15739035 12608943 12162507 10692979

Sources:
PharmGKB
TRIPHENYLSTANNANOL VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
FEPRAZONE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DIHYDROTANSHINONE I VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHRYSOPHANOL VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL1426508 VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
FLUAZINAM VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
OXIDOPAMINE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
BENSERAZIDE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DIMETHYL GAMBOGATE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ANAZOLENE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TRIBUTYLTIN-OXIDE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
LAPACHOL VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL1489812 VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
4-METHYLDAPHNETIN VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL1232076 VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL169233 VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ALAZANINE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PHANQUONE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TIOXOLONE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
LITHOCHOLIC ACID VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
24818857

Sources:
DTC
EDARAVONE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PHOSMET VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
2-ARACHIDONOYLGLYCEROL VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
2-BENZOYL-5-METHOXYBENZOQUINONE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PHENACYL CHLORIDE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ETHACRIDINE LACTATE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
RETINYL ACETATE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL1549738 VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PHENYLSTIBONIC ACID VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CARNOSIC ACID VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DEFERASIROX VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
30651574

Sources:
PharmGKB
MALATHION VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHLORPYRIFOS VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
AGROCLAVINE VDR

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEMATOXYLIN VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
GAMOLENIC ACID VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DIAMIDE VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CANDESARTAN CILEXETIL VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL1334465 VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL271023 VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DOCONEXENT VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL388979 VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
2'-HYDROXYCHALCONE VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
BENZYL ISOTHIOCYANATE VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ORTHO-PHTHALALDEHYDE VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DITHIOLETHIONE VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL565893 VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
SAPPANONE A DIMETHYL ETHER VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
R-N-PROPYLNORAPOMORPHINE VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
OBTUSAQUINONE VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
METHYLERGONOVINE VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TYRPHOSTIN 1 VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL1310701 VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DIPYRITHIONE VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
GATIFLOXACIN VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL126804 VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL1459280 VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL59030 VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL118678 VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL153057 VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CARBARIL VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL1546223 VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CEFOTAXIME VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CAMBINOL VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TANSHINONE IIA SULFONATE VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
KETOCONAZOLE VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
2546501

Sources:
DTC NCI
OXYTETRACYCLINE HYDROCHLORIDE VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
GUANIDINONALTRINDOLE VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PANTOPRAZOLE VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL122355 VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL17201 VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
SULFOBROMOPHTHALEIN VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL38508 VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
NORSTICTIC ACID VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ZAPA VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL600694 VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
SOFALCONE VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
MEDROXYPROGESTERONE ACETATE VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9860300

Sources:
PharmGKB
CHEMBL119878 VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TETROQUINONE VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL457504 VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ROSE BENGAL VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
2,6-DIMETHOXYQUINONE VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL596380 VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
BITHIONOLOXIDE VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CYCLOVALONE VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
BROMOENOL LACTONE VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL602213 VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
4-AMINOPHENOL VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
7,8-DIHYDROXYFLAVONE VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL284609 VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TETRABROMOBENZOTRIAZOLE VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
IODOPHTHALEIN VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
(S)APOMORPHINE VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HOMIDIUM VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CADMIUM ACETATE VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
THIOTEPA VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
BIS(DIMETHYLAMINETHIOCARBONYL)MONOSULFIDE VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ALITRETINOIN VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
2-MERCAPTOBENZOTHIAZOLE VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CATECHIN VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL166486 VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
BITHIONOLATE SODIUM VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
IODOQUINOL VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL421215 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DYCLONINE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
3R14S-OCHRATOXIN A VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ERYTHROSINE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TETRAIDOFLUORESCEIN VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL125044 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TYRPHOSTIN 51 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL1537417 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL1255944 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
RITANSERIN VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TRIMETREXATE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
METHYL 7-DESHYDROXYPYROGALLIN-4-CARBOXYLATE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TOLFENAMIC ACID VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PATULIN VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
BRIMONIDINE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL599255 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL581044 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
4-METHOXYDALBERGIONE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ERGOCRYPTINE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
KOPARIN VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL313737 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
SHIKONIN VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
METITEPINE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
METHYSERGIDE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
GOSSYPETIN VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL403183 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
U-0126 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL538798 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
3-METHOXYCATECHOL VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL1498652 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
RIBAVIRIN VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
27139837 25713999

Sources:
PharmGKB
PYRITHIONE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL1256813 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL580421 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
AURIN VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL1362503 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PROTOPORPHYRIN DISODIUM VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL1224755 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DIHYDROGAMBOGIC ACID VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
IRIGINOL HEXAACEATATE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
5,7-DIHYDROXYISOFLAVONE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ESTRAMUSTINE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ECONAZOLE NITRATE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ROTTLERIN VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL154580 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ISOTRETINOIN VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ANDROSTANOLONE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12532336

Sources:
NCI
CHEMBL116548 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TYRPHOSTIN 25 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHLOROTHALONIL VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL527584 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
NBQX VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
GUTHION VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
MICONAZOLE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
BAY-11-7085 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ARACHIDONIC ACID VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHELERYTHRINE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ETHACRYNIC ACID VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
KEPONE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
NITAZOXANIDE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
FUMARPROTOCETRARIC ACID VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
GALLIC ACID VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
RABEPRAZOLE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
SULFINPYRAZONE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ISOLIQUIRITIGENIN VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HYDROCORTISONE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
1647304 14705237

Sources:
NCI
ZIRAM VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
NANAOMYCIN VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
OXYPHENBUTAZONE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PYRROLIDINE DITHIOCARBAMATE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TANSHINONE IIA VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL601364 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CAPTAN VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
SANGUINARINE SULFATE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
E324 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
IRIGENOL VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
NITROXOLINE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PLUMBAGIN VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CAFFEINE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
11684540

Sources:
NCI
STAUROSPORINE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
7588324

Sources:
NCI
DEXAMETHASONE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10320522 20727239 18827005 15883634 15864137

Sources:
PharmGKB
APOMORPHINE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
IODOACETAMIDE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CEFACLOR VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PROTOAPIGENONE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PENTACHLOROPHENOL VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL1465049 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ZAFIRLUKAST VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CRYPTOTANSHINONE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
AMOXAPINE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PYRITHIONE ZINC VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
BENZBROMARONE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
FLUPIRTINE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CONGO RED VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL1567571 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
LOBARIC ACID VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
NISOLDIPINE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHLORANIL VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL24983 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PYROGALLOL VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ACRIFLAVINE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
BROMOCRIPTINE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DYCLONINE HYDROCHLORIDE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DACTINOMYCIN VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DOCEBENONE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ACITRETIN VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
BENSERAZIDE HYDROCHLORIDE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
INAMRINONE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TYRPHOSTIN AG 879 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
GENTIAN VIOLET VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ARACHIDONOYL GLYCINE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL523200 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
RABEPRAZOLE SODIUM VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
OXIDOPAMINE HYDROCHLORIDE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CAMPTOTHECIN VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
7510956

Sources:
NCI
CHEMBL322970 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
STICTIC ACID VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
WARFARIN VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
29298995

Sources:
PharmGKB
TESTOSTERONE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12796696

Sources:
NCI
TPCK VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL35482 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15930183

Sources:
NCI
RITONAVIR VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
LINOLENIC ACID VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CALCIMYCIN VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL56731 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
MERCURIC CHLORIDE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PHENYLMERCURIC ACETATE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL72365 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
JUGLONE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
STREPTONIGRIN VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
OXCARBAZEPINE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
MESALAMINE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PURPURIN VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TYRPHOSTIN A9 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TYRPHOSTIN 23 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
SLAZINIC ACID VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
BITHIONOL VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
NOREPINEPHRINE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL515505 VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
THIRAM VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
THIMEROSAL VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CURCUMIN VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23276449 20153625

Sources:
DTC
PYROGALLOL RED VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PROTOPORPHYRIN VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DEPHOSTATIN VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
SANGUINARIUM VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
LANSOPRAZOLE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HAEMATOXYLIN VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
9,10-PHENANTHRENEQUINONE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
LAPACHONE VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
WORTMANNIN VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL56393 VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
4-CHLOROMERCURIBENZOIC ACID VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
MENADIONE VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ELLAGIC ACID VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ISOPROTERENOL VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TRETINOIN VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TAMOXIFEN VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
1315250

Sources:
NCI
GW7647 VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HOMIDIUM BROMIDE VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EPINEPHRINE VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
SURAMIN VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL592124 VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CYCLOSPORINE VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10609555

Sources:
NCI
AURINTRICARBOXYLIC ACID VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
MITOXANTRONE HYDROCHLORIDE VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
OMEPRAZOLE VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DAUNORUBICIN HYDROCHLORIDE VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EBSELEN VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL505670 VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
NORDIHYDROGUAIARETIC ACID VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PURPUROGALLIN VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
MIDAZOLAM VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
DISULFIRAM VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
LOVASTATIN VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
NIFEDIPINE VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
GOSSYPOL VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL429095 VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
IRINOTECAN VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
CARBOPLATIN VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
METHOTREXATE VDR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

Ensembl: ENSG00000111424
- Version: 101_38
Alternate Names:

VDR Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
TEND: P11473
- Version: 01-August-2011
Alternate Names:

VDR Gene Symbol

7421 Entrez Gene Id

P11473 Uniprot Accession

Gene Info:

Target Main Class Receptors

Target Subclass Nuclear receptor

Publications:
RussLampel: ENSG00000111424
- Version: 26-July-2011
Alternate Names:

VDR Display Id

VITAMIN D3 RECEPTOR (VDR) (1,25-DIHYDROXYVITAMIN D3 RECEPTOR). [SOURCE:UNIPROT/SWISSPROT;ACC:P11473] Description

ENSG00000111424 Ensembl Gene Id

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:
TdgClinicalTrial: P11473
- Version: January-2014
Alternate Names:

VDR Gene Symbol

Gene Info:

Target Class Receptors

Target Subclass Nuclear receptor

Publications:
BaderLabGenes: VDR
- Version: February-2014
Alternate Names:

7421 Entrez Gene ID

Gene Info:

Initial Gene Query NR1I1

Counted Citations from 1950-2000 2939

Gene Categories:

NUCLEAR HORMONE RECEPTOR

Publications:
HopkinsGroom: P11473
- Version: 11-September-2012
Alternate Names:

VDR Uniprot Gene Name

7421 Entrez Gene Id

VITAMIN D3 RECEPTOR Uniprot Protein Name

Gene Info:

Uniprot Evidence 1: Evidence at protein level

Human Readable Name DRUGGABLE GENOME

Interpro Acc IPR000536

Gene Categories:

NUCLEAR HORMONE RECEPTOR, DRUGGABLE GENOME

Publications:

PharmGKB: VDR

Version: 18-August-2020

Alternate Names:

PA37301 PharmGKB ID

Gene Info:

Publications:

Abrams SA et al., 2005, Vitamin D receptor Fok1 polymorphisms affect calcium absorption, kinetics, and bone mineralization rates during puberty., J Bone Miner Res

Hubner RA et al., 2008, Dairy products, polymorphisms in the vitamin D receptor gene and colorectal adenoma recurrence., Int J Cancer

van Etten E et al., 2007, The vitamin D receptor gene FokI polymorphism: functional impact on the immune system., Eur J Immunol

TTD: Vitamin D3 receptor
- Version: 2020.06.01
Alternate Names:

VDR TTD Gene Abbreviation

T34234 TTD Target ID

Gene Info:

Publications:

Terai K et al., 2009, Vascular calcification and secondary hyperparathyroidism of severe chronic kidney disease and its relation to serum phosphate and calcium levels., Br J Pharmacol

NCI: VDR

Version: 14-September-2017

Alternate Names:

Gene Info:

Publications:

Leman et al., 2003, Regulation of androgen and vitamin d receptors by 1,25-dihydroxyvitamin D3 in human prostate epithelial and stromal cells., J. Urol.

Reinhardt et al., 1989, Ketoconazole inhibits self-induced metabolism of 1,25-dihydroxyvitamin D3 and amplifies 1,25-dihydroxyvitamin D3 receptor up-regulation in rat osteosarcoma cells., Arch. Biochem. Biophys.

Palomba et al., 2003, Effectiveness of alendronate treatment in postmenopausal women with osteoporosis: relationship with BsmI vitamin D receptor genotypes., Clin. Endocrinol. (Oxf)

DTC: VDR

Version: 02-September-2020

Alternate Names:

Gene Info:

Publications:

Lamblin M et al., 2010, Vitamin D receptor agonist/histone deacetylase inhibitor molecular hybrids., Bioorg Med Chem

Batie S et al., 2013, Synthesis and biological evaluation of halogenated curcumin analogs as potential nuclear receptor selective agonists., Bioorg Med Chem

Wongmayura A et al., 2012, Novel vitamin D receptor ligands bearing a spherical hydrophobic core structure--comparison of bicyclic hydrocarbon derivatives with boron cluster derivatives., Bioorg Med Chem Lett

HingoraniCasas: ENSG00000111424
- Version: 31-May-2017
Alternate Names:

ENSG00000111424 Gene Symbol

VDR Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
ChemblInteractions: NR1I1
- Version: chembl_23
Alternate Names:

NR1I1 GENE_SYMBOL

VDR GENE_SYMBOL

Vitamin D3 receptor UNIPROT

Gene Info:

Publications:
GO: VDR
- Version: 01-February-2022
Alternate Names:

NR1I1 GO Gene Synonym

Gene Info:

Gene Categories:

NUCLEAR HORMONE RECEPTOR

Publications:
dGene: VDR
- Version: 27-Jun-2013
Alternate Names:

7421 Gene ID

NR1I1 dGene Synonym

Gene Info:

Gene Categories:

NUCLEAR HORMONE RECEPTOR

Publications:
Pharos: VDR
- Version: 01-February-2022
Alternate Names:

Vitamin D3 receptor Gene Name

P11473 UniProt ID

Gene Info:

Gene Categories:

NUCLEAR HORMONE RECEPTOR, TRANSCRIPTION FACTOR

Publications:

Trial Name	paricalcitol , Zemplar
Novel drug target	Established target
Mechanism of Interaction	Vitamin D receptor agonist

Direct Interaction	yes
Mechanism of Interaction	Vitamin D receptor agonist
Trial Name	doxercalciferol , Hectorol

Trial Name	DN-101,Asentar
Novel drug target	Established target
Trial Name	calcitriol, vitamin D3 derivative,Silkis, Vectical

Trial Name	inecalcitol, TX-522
Novel drug target	Established target
Mechanism of Interaction	Vitamin D receptor agonist

Trial Name	eldecalcitol, ED-71
Novel drug target	Established target

Trial Name	calcipotriene + betamethasone dipropionate, LEO-80185,Taclonex, Xamiol
Novel drug target	Established target
Mechanism of Interaction	Vitamin D receptor agonist

VDR	Display Id
VITAMIN D3 RECEPTOR (VDR) (1,25-DIHYDROXYVITAMIN D3 RECEPTOR). [SOURCE:UNIPROT/SWISSPROT;ACC:P11473]	Description
ENSG00000111424	Ensembl Gene Id

VDR	Uniprot Gene Name
7421	Entrez Gene Id
VITAMIN D3 RECEPTOR	Uniprot Protein Name

agonist (activating)
antagonist (inhibitory)

agonist (activating)
suppressor (inhibitory)

agonist (activating)
antagonist (inhibitory)

VDR Gene Record

VDR 7421 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

Interaction Types & Directionality: agonist (activating) antagonist (inhibitory)

Interaction Info: Trial Name - Novel drug target Established target

PMIDs: 17016423 17139284 11752352 10707958 9933478 21651652 21418277 20716226 20500803 19647104 17763859 17274004 15864137 15861036 15739035 15295697

Sources: TdgClinicalTrial TEND PharmGKB TTD

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 19020788 18443790 12608943 12162507 10707958 10692979 9933478 21418277 17274004 15861036 15739035

Sources: PharmGKB

Interaction Types & Directionality: agonist (activating)

Interaction Info: Novel drug target Established target Trial Name -

PMIDs: 1336906 11752352 8380156 17016423 17139284 20525913

Sources: TdgClinicalTrial TEND TTD

Interaction Types & Directionality: agonist (activating)

Interaction Info: Trial Name paricalcitol , Zemplar Novel drug target Established target Mechanism of Interaction Vitamin D receptor agonist

PMIDs: 16076355 20204178 11752352 19494617 17016423 17139284

Sources: TdgClinicalTrial ChemblInteractions TEND TTD

Interaction Types & Directionality: agonist (activating) suppressor (inhibitory)

Interaction Info: Direct Interaction yes Mechanism of Interaction Vitamin D receptor agonist Trial Name doxercalciferol , Hectorol

PMIDs: 21169421

Sources: TdgClinicalTrial ChemblInteractions TTD

Interaction Types & Directionality: agonist (activating)

Interaction Info: Mechanism of Interaction Vitamin D receptor agonist Direct Interaction yes

PMIDs: 17016423 17139284

Sources: ChemblInteractions TTD

Interaction Types & Directionality: agonist (activating) antagonist (inhibitory)

Interaction Info: Trial Name DN-101,Asentar Novel drug target Established target Trial Name calcitriol, vitamin D3 derivative,Silkis, Vectical

PMIDs: 10320522 9933478 333287 21651652 21418277 20727239 20716226 20500803 19647104 18827005 18470879 17763859 17274004 16210379 15883634 15864137 15861036 15739035 15295697 14685227 11450701 10707958 11158396 24818857 19309155 22285943 20883026 20452225 15503649 11752352

Sources: DTC TdgClinicalTrial ChemblInteractions NCI TEND PharmGKB TTD

Interaction Types & Directionality: agonist (activating)

Interaction Info: Novel drug target Established target Trial Name - Mechanism of Interaction Vitamin D receptor agonist

PMIDs: 17218095 17519354 16949927 20091647 11752352 18290715 17440943 17207992 20525913

Sources: TdgClinicalTrial ChemblInteractions TEND TTD

Interaction Types & Directionality: agonist (activating)

Interaction Info: Mechanism of Interaction Vitamin D receptor agonist Direct Interaction yes Trial Name Elocalcitol

PMIDs: 17241782

Sources: TdgClinicalTrial ChemblInteractions

Interaction Types & Directionality: agonist (activating)

Interaction Info: Trial Name inecalcitol, TX-522 Novel drug target Established target Mechanism of Interaction Vitamin D receptor agonist

PMIDs: 10592235

Sources: TdgClinicalTrial ChemblInteractions

Interaction Types & Directionality: agonist (activating)

Interaction Info: Mechanism of Interaction Vitamin D receptor agonist Direct Interaction yes

PMIDs: 10592235

Sources: ChemblInteractions

Interaction Types & Directionality: agonist (activating)

Interaction Info: Mechanism of Interaction Vitamin D receptor agonist Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions TTD

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15754350

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 20883026

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 20452225

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 12608943 19020788 18443790 15739035 12162507 11450701 10692979 9933478 21651652 20500803 18470879 16210379 14685227

Sources: NCI PharmGKB

Interaction Types & Directionality: agonist (activating)

Interaction Info:

PMIDs: 15503649 11752352

Sources: TTD

Interaction Types & Directionality: agonist (activating)

Interaction Info: Mechanism of Interaction Vitamin D receptor agonist Direct Interaction yes

PMIDs: 11752352 15503649

Sources: ChemblInteractions TTD

Interaction Types & Directionality: n/a

Interaction Info:

Interaction Types & Directionality:

agonist (activating)

antagonist (inhibitory)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
17016423 17139284 11752352 10707958 9933478 21651652 21418277 20716226 20500803 19647104 17763859 17274004 15864137 15861036 15739035 15295697

Sources:
TdgClinicalTrial TEND PharmGKB TTD

Interaction Types & Directionality:

n/a

PMIDs:
19020788 18443790 12608943 12162507 10707958 10692979 9933478 21418277 17274004 15861036 15739035

Sources:
PharmGKB

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Novel drug target Established target

Trial Name -

PMIDs:
1336906 11752352 8380156 17016423 17139284 20525913

Sources:
TdgClinicalTrial TEND TTD

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Trial Name paricalcitol , Zemplar

Novel drug target Established target

Mechanism of Interaction Vitamin D receptor agonist

PMIDs:
16076355 20204178 11752352 19494617 17016423 17139284

Sources:
TdgClinicalTrial ChemblInteractions TEND TTD

Interaction Types & Directionality:

agonist (activating)

suppressor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Vitamin D receptor agonist

Trial Name doxercalciferol , Hectorol

PMIDs:
21169421

Sources:
TdgClinicalTrial ChemblInteractions TTD

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Mechanism of Interaction Vitamin D receptor agonist

Direct Interaction yes

PMIDs:
17016423 17139284

Sources:
ChemblInteractions TTD

Interaction Types & Directionality:

agonist (activating)

antagonist (inhibitory)

Interaction Info:

Trial Name DN-101,Asentar

Novel drug target Established target

Trial Name calcitriol, vitamin D3 derivative,Silkis, Vectical

PMIDs:
10320522 9933478 333287 21651652 21418277 20727239 20716226 20500803 19647104 18827005 18470879 17763859 17274004 16210379 15883634 15864137 15861036 15739035 15295697 14685227 11450701 10707958 11158396 24818857 19309155 22285943 20883026 20452225 15503649 11752352

Sources:
DTC TdgClinicalTrial ChemblInteractions NCI TEND PharmGKB TTD

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Novel drug target Established target

Trial Name -

Mechanism of Interaction Vitamin D receptor agonist

PMIDs:
17218095 17519354 16949927 20091647 11752352 18290715 17440943 17207992 20525913

Sources:
TdgClinicalTrial ChemblInteractions TEND TTD

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Mechanism of Interaction Vitamin D receptor agonist

Direct Interaction yes

Trial Name Elocalcitol

PMIDs:
17241782

Sources:
TdgClinicalTrial ChemblInteractions

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Trial Name inecalcitol, TX-522

Novel drug target Established target

Mechanism of Interaction Vitamin D receptor agonist

PMIDs:
10592235

Sources:
TdgClinicalTrial ChemblInteractions

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Mechanism of Interaction Vitamin D receptor agonist

Direct Interaction yes

PMIDs:
10592235

Sources:
ChemblInteractions

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Mechanism of Interaction Vitamin D receptor agonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD

Interaction Types & Directionality:

n/a

PMIDs:
15754350

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
20883026

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
20452225

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
12608943 19020788 18443790 15739035 12162507 11450701 10692979 9933478 21651652 20500803 18470879 16210379 14685227

Sources:
NCI PharmGKB

Interaction Types & Directionality:

agonist (activating)

PMIDs:
15503649 11752352

Sources:
TTD

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Mechanism of Interaction Vitamin D receptor agonist

Direct Interaction yes

PMIDs:
11752352 15503649

Sources:
ChemblInteractions TTD

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found