DGIdb - 2-MERCAPTOBENZOTHIAZOLE Drug Record

2-MERCAPTOBENZOTHIAZOLE chembl:CHEMBL111654

Alternate Names:

BENZOTHIAZOLE-2-THIOL
2-MERCAPTOBENZOTHIOAZOLE
2-MERCAPTOBENZOTHIAZOLE

Drug Info:

Drug Type	small molecule
Drug Groups	approved
Drug Groups	experimental
Drug Groups	vet_approved
Drug Categories	anti-infective agents
Drug Categories	cell-mediated immunity
Drug Categories	heterocyclic compounds, fused-ring
Drug Categories	increased histamine release
Drug Categories	standardized chemical allergen
Drug Categories	sulfur compounds
Drug Categories	thiazoles

(0 More Sources)

Publications:

Fung SP et al., 2013, Discovery and characterisation of hydrazines as inhibitors of the immune suppressive enzyme, indoleamine 2,3-dioxygenase 1 (IDO1)., Bioorg Med Chem
Leonard JA et al., 2016, Estimating Margin of Exposure to Thyroid Peroxidase Inhibitors Using High-Throughput in vitro Data, High-Throughput Exposure Modeling, and Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling., Toxicol Sci

2-MERCAPTOBENZOTHIAZOLE TPO

Interaction Score: 1.8

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
26865668

Sources:
DrugBank
2-MERCAPTOBENZOTHIAZOLE IDO1

Interaction Score: 0.79

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
24262887

Sources:
DTC
2-MERCAPTOBENZOTHIAZOLE KAT2A

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
2-MERCAPTOBENZOTHIAZOLE HPGD

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
2-MERCAPTOBENZOTHIAZOLE KDM4E

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
2-MERCAPTOBENZOTHIAZOLE ALDH1A1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
2-MERCAPTOBENZOTHIAZOLE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
2-MERCAPTOBENZOTHIAZOLE NFE2L2

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
2-MERCAPTOBENZOTHIAZOLE EHMT2

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

DrugBank: DB11496

Version: 5.1.7

Alternate Names:

2-MERCAPTOBENZOTHIAZOLE DrugBank Drug Name

149-30-4 CAS Number

Captax Drug Brand

Drug Info:

Drug Type small molecule

Drug Groups approved

Drug Groups experimental

Publications:

Leonard JA et al., 2016, Estimating Margin of Exposure to Thyroid Peroxidase Inhibitors Using High-Throughput in vitro Data, High-Throughput Exposure Modeling, and Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling., Toxicol Sci

DTC: 2-MERCAPTOBENZOTHIAZOLE
- Version: 02-September-2020
Alternate Names:

CHEMBL111654 ChEMBL Drug ID

Drug Info:

Publications:

Fung SP et al., 2013, Discovery and characterisation of hydrazines as inhibitors of the immune suppressive enzyme, indoleamine 2,3-dioxygenase 1 (IDO1)., Bioorg Med Chem
ChemblDrugs: chembl:CHEMBL111654
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

2-MERCAPTOBENZOTHIAZOLE	DrugBank Drug Name
149-30-4	CAS Number
Captax	Drug Brand

2-MERCAPTOBENZOTHIAZOLE Drug Record

2-MERCAPTOBENZOTHIAZOLE chembl:CHEMBL111654

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info:

PMIDs: 26865668

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 24262887

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

DrugBank: DB11496

Alternate Names: 2-MERCAPTOBENZOTHIAZOLE DrugBank Drug Name 149-30-4 CAS Number Captax Drug Brand

Drug Info: Drug Type small molecule Drug Groups approved Drug Groups experimental

Publications: Leonard JA et al., 2016, Estimating Margin of Exposure to Thyroid Peroxidase Inhibitors Using High-Throughput in vitro Data, High-Throughput Exposure Modeling, and Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling., Toxicol Sci

DTC: 2-MERCAPTOBENZOTHIAZOLE

Alternate Names: CHEMBL111654 ChEMBL Drug ID

Drug Info:

Publications: Fung SP et al., 2013, Discovery and characterisation of hydrazines as inhibitors of the immune suppressive enzyme, indoleamine 2,3-dioxygenase 1 (IDO1)., Bioorg Med Chem

ChemblDrugs: chembl:CHEMBL111654

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

inhibitor (inhibitory)

PMIDs:
26865668

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
24262887

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Alternate Names:

2-MERCAPTOBENZOTHIAZOLE DrugBank Drug Name

149-30-4 CAS Number

Captax Drug Brand

Drug Info:

Drug Type small molecule

Drug Groups approved

Drug Groups experimental

Publications:

Leonard JA et al., 2016, Estimating Margin of Exposure to Thyroid Peroxidase Inhibitors Using High-Throughput in vitro Data, High-Throughput Exposure Modeling, and Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling., Toxicol Sci

Alternate Names:

CHEMBL111654 ChEMBL Drug ID

Publications:

Fung SP et al., 2013, Discovery and characterisation of hydrazines as inhibitors of the immune suppressive enzyme, indoleamine 2,3-dioxygenase 1 (IDO1)., Bioorg Med Chem