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2-MERCAPTOBENZOTHIAZOLE Drug Record

  • Summary
  • Interactions
  • Claims
  • 2-MERCAPTOBENZOTHIAZOLE chembl:CHEMBL111654

    Alternate Names:

    BENZOTHIAZOLE-2-THIOL
    2-MERCAPTOBENZOTHIOAZOLE
    2-MERCAPTOBENZOTHIAZOLE

    Drug Info:

    Drug Type small molecule
    Drug Groups approved
    Drug Groups experimental
    Drug Groups vet_approved
    Drug Categories anti-infective agents
    Drug Categories cell-mediated immunity
    Drug Categories heterocyclic compounds, fused-ring
    Drug Categories increased histamine release
    Drug Categories standardized chemical allergen
    Drug Categories sulfur compounds
    Drug Categories thiazoles
    (0 More Sources)

    Publications:

    Fung SP et al., 2013, Discovery and characterisation of hydrazines as inhibitors of the immune suppressive enzyme, indoleamine 2,3-dioxygenase 1 (IDO1)., Bioorg Med Chem
    Leonard JA et al., 2016, Estimating Margin of Exposure to Thyroid Peroxidase Inhibitors Using High-Throughput in vitro Data, High-Throughput Exposure Modeling, and Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling., Toxicol Sci
  • 2-MERCAPTOBENZOTHIAZOLE   TPO

    Interaction Score: 1.8

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    26865668


    Sources:
    DrugBank

  • 2-MERCAPTOBENZOTHIAZOLE   IDO1

    Interaction Score: 0.79

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    24262887


    Sources:
    DTC

  • 2-MERCAPTOBENZOTHIAZOLE   KAT2A

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • 2-MERCAPTOBENZOTHIAZOLE   HPGD

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • 2-MERCAPTOBENZOTHIAZOLE   KDM4E

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • 2-MERCAPTOBENZOTHIAZOLE   ALDH1A1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • 2-MERCAPTOBENZOTHIAZOLE   VDR

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • 2-MERCAPTOBENZOTHIAZOLE   NFE2L2

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • 2-MERCAPTOBENZOTHIAZOLE   EHMT2

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • DrugBank: DB11496

    • Version: 5.1.7

    Alternate Names:
    2-MERCAPTOBENZOTHIAZOLE DrugBank Drug Name
    149-30-4 CAS Number
    Captax Drug Brand

    Drug Info:
    Drug Type small molecule
    Drug Groups approved
    Drug Groups experimental

    Publications:
    Leonard JA et al., 2016, Estimating Margin of Exposure to Thyroid Peroxidase Inhibitors Using High-Throughput in vitro Data, High-Throughput Exposure Modeling, and Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling., Toxicol Sci

  • DTC: 2-MERCAPTOBENZOTHIAZOLE

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL111654 ChEMBL Drug ID

    Drug Info:

    Publications:
    Fung SP et al., 2013, Discovery and characterisation of hydrazines as inhibitors of the immune suppressive enzyme, indoleamine 2,3-dioxygenase 1 (IDO1)., Bioorg Med Chem

  • ChemblDrugs: chembl:CHEMBL111654

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21