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ABACAVIR Drug Record

  • Summary
  • Interactions
  • Claims
  • ABACAVIR chembl:CHEMBL1380 Approved

    Alternate Names:

    EPZICOM
    ZIAGEN
    ABACAVIR
    C14H18N6O
    ATC CODE J05AF06
    {(1S-CIS)-4-[2-AMINO-6-(CYCLOPROPYLAMINO)-9H-PURIN-9-YL]CYCLOPENT-2-EN-1-YL}METHANOL
    ABC
    ABACAVIR SULFATE
    ATCVET CODE QJ05AF06
    chemidplus:136470-78-5
    rxcui:190521
    drugbank:01048
    chembl:CHEMBL1380
    pubchem.compound:441300

    Drug Info:

    (1 More Sources)

    Publications:

    Weiss J et al., 2007, Inhibition of MRP1/ABCC1, MRP2/ABCC2, and MRP3/ABCC3 by nucleoside, nucleotide, and non-nucleoside reverse transcriptase inhibitors., Drug Metab Dispos
    Yang L et al., 2009, Harvesting candidate genes responsible for serious adverse drug reactions from a chemical-protein interactome., PLoS Comput Biol
    Barbarino JM et al., 2014, PharmGKB summary: abacavir pathway., Pharmacogenet Genomics
  • ABACAVIR   LST1

    Interaction Score: 5.62

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • ABACAVIR   ADH1B

    Interaction Score: 2.81

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    24625462


    Sources:
    PharmGKB

  • ABACAVIR   LTB

    Interaction Score: 2.81

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • ABACAVIR   ADH1A

    Interaction Score: 2.81

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    24625462


    Sources:
    PharmGKB

  • ABACAVIR   ADH1C

    Interaction Score: 2.25

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    24625462


    Sources:
    PharmGKB

  • ABACAVIR   ADK

    Interaction Score: 1.87

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    24625462


    Sources:
    PharmGKB

  • ABACAVIR   LTA

    Interaction Score: 1.41

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • ABACAVIR   HLA-B

    Interaction Score: 0.45

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    19629158


    Sources:
    FDA

  • ABACAVIR   ABCC3

    Interaction Score: 0.45

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17172311


    Sources:
    DTC

  • ABACAVIR   ABCC1

    Interaction Score: 0.22

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17172311


    Sources:
    DTC

  • ABACAVIR   ABCC2

    Interaction Score: 0.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17172311


    Sources:
    DTC

  • DTC: ABACAVIR

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL1380 ChEMBL Drug ID

    Drug Info:

    Publications:
    Weiss J et al., 2007, Inhibition of MRP1/ABCC1, MRP2/ABCC2, and MRP3/ABCC3 by nucleoside, nucleotide, and non-nucleoside reverse transcriptase inhibitors., Drug Metab Dispos

  • PharmGKB: abacavir

    • Version: 18-August-2020

    Alternate Names:

    Drug Info:

    Publications:
    Barbarino JM et al., 2014, PharmGKB summary: abacavir pathway., Pharmacogenet Genomics

  • TTD: Abacavir

    • Version: 2020.06.01

    Alternate Names:
    D0A4IJ TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL1380

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

  • FDA: Abacavir

    • Version: 04-September-2020

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21