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ACAMPROSATE Drug Record

  • Summary
  • Interactions
  • Claims
  • ACAMPROSATE chembl:CHEMBL1201293 ApprovedAntineoplastic

    Alternate Names:

    ACAMPROSATE
    ACAMPROSATO
    N-ACETYLHOMOTAURINE
    CAMPRAL®
    3-ACETAMIDO-1-PROPANESULFONIC ACID
    ACAMPROSATUM
    N-ACETYL HOMOTAURINE
    chembl:CHEMBL1201293
    pubchem.compound:71158
    rxcui:82819
    drugbank:00659
    chemidplus:77337-76-9

    Drug Info:

    Drug Categories drugs used in alcohol dependence
    Drug Categories alkanes
    Drug Indications antineoplastic agent
    FDA Approval approved
    Drug Class Small Molecule
    Drug Indications for treatment of alcohol-dependance
    Drug Categories miscellaneous central nervous system agents
    (1 More Sources)

    Publications:

    Williams, 2005, Medications for treating alcohol dependence., Am Fam Physician
    Witkiewitz et al., 2012, Acamprosate for treatment of alcohol dependence: mechanisms, efficacy, and clinical utility., Ther Clin Risk Manag
    Mann et al., 2008, Acamprosate: recent findings and future research directions., Alcohol. Clin. Exp. Res.
    De Witte et al., 2005, Neuroprotective and abstinence-promoting effects of acamprosate: elucidating the mechanism of action., CNS Drugs
    Karpyak VM et al., 2014, Genetic markers associated with abstinence length in alcohol-dependent subjects treated with acamprosate., Transl Psychiatry
  • ACAMPROSATE   GRM5

    Interaction Score: 1.7

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Trial Name acamprosate,Campral
    Novel drug target Established target

    PMIDs:
    15963001


    Sources:
    TdgClinicalTrial DrugBank

  • ACAMPROSATE   GRIN1

    Interaction Score: 0.51

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:

    PMIDs:
    22346357 18540918


    Sources:
    DrugBank

  • ACAMPROSATE   GRIN2B

    Interaction Score: 0.43

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25290263


    Sources:
    PharmGKB

  • ACAMPROSATE   GRIN3A

    Interaction Score: 0.28

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name acamprosate,Campral
    Novel drug target Established target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • ACAMPROSATE   GABRA1

    Interaction Score: 0.18

    Interaction Types & Directionality:
    positive modulator (activating)

    Interaction Info:

    PMIDs:
    16300039


    Sources:
    DrugBank

  • DrugBank: DB00659

    • Version: 5.1.7

    Alternate Names:
    ACAMPROSATE DrugBank Drug Name
    77337-76-9 CAS Number
    Acamprosate Calcium Drug Brand

    Drug Info:
    Drug Type small molecule
    Drug Groups approved
    Drug Groups investigational

    Publications:
    Williams, 2005, Medications for treating alcohol dependence., Am Fam Physician
    De Witte et al., 2005, Neuroprotective and abstinence-promoting effects of acamprosate: elucidating the mechanism of action., CNS Drugs
    Witkiewitz et al., 2012, Acamprosate for treatment of alcohol dependence: mechanisms, efficacy, and clinical utility., Ther Clin Risk Manag

  • TdgClinicalTrial: ACAMPROSATE

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications for treatment of alcohol-dependance
    Drug Class Small Molecule
    FDA Approval approved

    Publications:

  • PharmGKB: acamprosate

    • Version: 18-August-2020

    Alternate Names:

    Drug Info:

    Publications:
    Karpyak VM et al., 2014, Genetic markers associated with abstinence length in alcohol-dependent subjects treated with acamprosate., Transl Psychiatry

  • TTD: Acamprosate

    • Version: 2020.06.01

    Alternate Names:
    D0GC2M TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL1201293

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2021-04-13