DGIdb - ADENOSINE TRIPHOSPHATE Drug Record

ADENOSINE TRIPHOSPHATE chembl:CHEMBL14249

Alternate Names:

ADENOSINE TRIPHOSPHATE
ADENOSINE TRIPHOSPHATA
FOSFOBION
ADENOSINE 5'-TRIPHOSPHORATE
TRIPHOSPHADEN
GLUCOBASIN
ADENOSINE 5'-TRIPHOSPHATE
ADENYLPYROPHOSPHORATE
MYOTRIPHOS
[[[(2R,3R,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL]METHOXY-HYDROXY-PHOSPHORYL]OXY-HYDROXY-PHOSPHORYL]OXYPHOSPHONIC ACID
TRIADENYL
ADENYLPYROPHOSPHORIC ACID
ADENOSINE 5'-TRIPHOSPHORIC ACID
ADYNOL
CARDENOSINE
ADENOSINE 5' TRIPHOSPHATE
TRIPHOSPHORIC ACID ADENOSINE ESTER
5'-(TETRAHYDROGEN TRIPHOSPHATE) ADENOSINE
ADEPHOS
({[({[(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYOXOLAN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL)OXY](HYDROXY)PHOSPHORYL}OXY)PHOSPHONIC ACID
ADENOSINE-5'-TRIPHOSPHATE
ADETOL
STRIADYNE
H4ATP
ATP
ATRIPHOS
ATIPI
5'-ATP
[[[(2R,3R,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHOXY-HYDROXY-PHOSPHORYL]OXY-HYDROXY-PHOSPHORYL]OXYPHOSPHONIC ACID
PHOSPHOBION
pubchem.compound:5957
drugbank:00171
chembl:CHEMBL14249
chemidplus:56-65-5
rxcui:318

Drug Info:

(0 More Sources)

Publications:

Adrián FJ et al., 2006, Allosteric inhibitors of Bcr-abl-dependent cell proliferation., Nat Chem Biol
Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
Xiao Z et al., 2011, P2Y11 impairs cell proliferation by induction of cell cycle arrest and sensitizes endothelial cells to cisplatin-induced cell death., J Cell Biochem

ADENOSINE TRIPHOSPHATE P2RX4

Interaction Score: 1.88

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Agonist

Endogenous Drug? True

Direct Interaction? False

PMIDs:
None found

Sources:
GuideToPharmacology
ADENOSINE TRIPHOSPHATE P2RX1

Interaction Score: 1.88

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Agonist

Endogenous Drug? True

Direct Interaction? False

PMIDs:
None found

Sources:
GuideToPharmacology
ADENOSINE TRIPHOSPHATE P2RY11

Interaction Score: 1.25

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? True

Direct Interaction? False

PMIDs:
21503959

Sources:
GuideToPharmacology
ADENOSINE TRIPHOSPHATE ITPR1

Interaction Score: 1.25

Interaction Types & Directionality:

activator (activating)

Interaction Info:

Interaction Context cytosolic

Specific Action of the Ligand None

Details of Interaction < mM range

PMIDs:
None found

Sources:
GuideToPharmacology
ADENOSINE TRIPHOSPHATE P2RY13

Interaction Score: 0.94

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? True

PMIDs:
None found

Sources:
GuideToPharmacology
ADENOSINE TRIPHOSPHATE GPR17

Interaction Score: 0.94

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Agonist

Endogenous Drug? True

PMIDs:
None found

Sources:
GuideToPharmacology
ADENOSINE TRIPHOSPHATE P2RY4

Interaction Score: 0.94

Interaction Types & Directionality:

agonist (activating)

antagonist (inhibitory)

Interaction Info:

Specific Action of the Ligand Agonist

Endogenous Drug? True

Direct Interaction? False

PMIDs:
None found

Sources:
GuideToPharmacology
ADENOSINE TRIPHOSPHATE TRPM4

Interaction Score: 0.75

Interaction Types & Directionality:

blocker (inhibitory)

inhibitor (inhibitory)

Interaction Info:

Specific Action of the Ligand Antagonist

Endogenous Drug? True

PMIDs:
None found

Sources:
GuideToPharmacology
ADENOSINE TRIPHOSPHATE P2RX3

Interaction Score: 0.75

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Agonist

Endogenous Drug? True

Direct Interaction? False

PMIDs:
None found

Sources:
GuideToPharmacology
ADENOSINE TRIPHOSPHATE P2RY1

Interaction Score: 0.75

Interaction Types & Directionality:

agonist (activating)

antagonist (inhibitory)

Interaction Info:

Specific Action of the Ligand Partial agonist

Endogenous Drug? True

Specific Action of the Ligand Antagonist

PMIDs:
None found

Sources:
GuideToPharmacology
ADENOSINE TRIPHOSPHATE RYR3

Interaction Score: 0.75

Interaction Types & Directionality:

activator (activating)

Interaction Info:

Interaction Context cytosolic

Specific Action of the Ligand None

Details of Interaction endogenous; mM range

PMIDs:
None found

Sources:
GuideToPharmacology
ADENOSINE TRIPHOSPHATE P2RY2

Interaction Score: 0.42

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? True

Direct Interaction? False

PMIDs:
None found

Sources:
GuideToPharmacology
ADENOSINE TRIPHOSPHATE RYR2

Interaction Score: 0.38

Interaction Types & Directionality:

activator (activating)

Interaction Info:

Interaction Context cytosolic

Specific Action of the Ligand None

Details of Interaction endogenous; mM range

PMIDs:
None found

Sources:
GuideToPharmacology
ADENOSINE TRIPHOSPHATE P2RX7

Interaction Score: 0.34

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Direct Interaction? False

Endogenous Drug? True

Specific Action of the Ligand Agonist

PMIDs:
None found

Sources:
GuideToPharmacology
ADENOSINE TRIPHOSPHATE ABL1

Interaction Score: 0.27

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
16415863 11752352 17139284 17016423

Sources:
DTC
ADENOSINE TRIPHOSPHATE HSPA8

Interaction Score: 0.27

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ADENOSINE TRIPHOSPHATE RYR1

Interaction Score: 0.23

Interaction Types & Directionality:

activator (activating)

Interaction Info:

Interaction Context cytosolic

Specific Action of the Ligand None

Details of Interaction endogenous; mM range

PMIDs:
None found

Sources:
GuideToPharmacology

DTC: ADENOSINE TRIPHOSPHATE
- Version: 02-September-2020
Alternate Names:

CHEMBL14249 ChEMBL Drug ID

Drug Info:

Publications:

Adrián FJ et al., 2006, Allosteric inhibitors of Bcr-abl-dependent cell proliferation., Nat Chem Biol
GuideToPharmacology: 135651446
- Version: 29-September-2020
Alternate Names:

ATP GuideToPharmacology Ligand Name

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL14249
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

Specific Action of the Ligand	Agonist
Endogenous Drug?	True
Direct Interaction?	False

Specific Action of the Ligand	Full agonist
Endogenous Drug?	True
Direct Interaction?	False

Interaction Context	cytosolic
Specific Action of the Ligand	None
Details of Interaction	< mM range

Specific Action of the Ligand	Partial agonist
Endogenous Drug?	True
Specific Action of the Ligand	Antagonist

agonist (activating)
antagonist (inhibitory)

blocker (inhibitory)
inhibitor (inhibitory)

agonist (activating)
antagonist (inhibitory)

ADENOSINE TRIPHOSPHATE Drug Record

ADENOSINE TRIPHOSPHATE chembl:CHEMBL14249

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: agonist (activating)

Interaction Info: Specific Action of the Ligand Agonist Endogenous Drug? True Direct Interaction? False

PMIDs: None found

Sources: GuideToPharmacology

Interaction Types & Directionality: agonist (activating)

Interaction Info: Specific Action of the Ligand Agonist Endogenous Drug? True Direct Interaction? False

PMIDs: None found

Sources: GuideToPharmacology

Interaction Types & Directionality: agonist (activating)

Interaction Info: Specific Action of the Ligand Full agonist Endogenous Drug? True Direct Interaction? False

PMIDs: 21503959

Sources: GuideToPharmacology

Interaction Types & Directionality: activator (activating)

Interaction Info: Interaction Context cytosolic Specific Action of the Ligand None Details of Interaction < mM range

PMIDs: None found

Sources: GuideToPharmacology

Interaction Types & Directionality: agonist (activating)

Interaction Info: Specific Action of the Ligand Full agonist Endogenous Drug? True

PMIDs: None found

Sources: GuideToPharmacology

Interaction Types & Directionality: agonist (activating)

Interaction Info: Specific Action of the Ligand Agonist Endogenous Drug? True

PMIDs: None found

Sources: GuideToPharmacology

Interaction Types & Directionality: agonist (activating) antagonist (inhibitory)

Interaction Info: Specific Action of the Ligand Agonist Endogenous Drug? True Direct Interaction? False

PMIDs: None found

Sources: GuideToPharmacology

Interaction Types & Directionality: blocker (inhibitory) inhibitor (inhibitory)

Interaction Info: Specific Action of the Ligand Antagonist Endogenous Drug? True

PMIDs: None found

Sources: GuideToPharmacology

Interaction Types & Directionality: agonist (activating)

Interaction Info: Specific Action of the Ligand Agonist Endogenous Drug? True Direct Interaction? False

PMIDs: None found

Sources: GuideToPharmacology

Interaction Types & Directionality: agonist (activating) antagonist (inhibitory)

Interaction Info: Specific Action of the Ligand Partial agonist Endogenous Drug? True Specific Action of the Ligand Antagonist

PMIDs: None found

Sources: GuideToPharmacology

Interaction Types & Directionality: activator (activating)

Interaction Info: Interaction Context cytosolic Specific Action of the Ligand None Details of Interaction endogenous; mM range

PMIDs: None found

Sources: GuideToPharmacology

Interaction Types & Directionality: agonist (activating)

Interaction Info: Specific Action of the Ligand Full agonist Endogenous Drug? True Direct Interaction? False

PMIDs: None found

Sources: GuideToPharmacology

Interaction Types & Directionality: activator (activating)

Interaction Info: Interaction Context cytosolic Specific Action of the Ligand None Details of Interaction endogenous; mM range

PMIDs: None found

Sources: GuideToPharmacology

Interaction Types & Directionality: agonist (activating)

Interaction Info: Direct Interaction? False Endogenous Drug? True Specific Action of the Ligand Agonist

PMIDs: None found

Sources: GuideToPharmacology

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info:

PMIDs: 16415863 11752352 17139284 17016423

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: activator (activating)

Interaction Info: Interaction Context cytosolic Specific Action of the Ligand None Details of Interaction endogenous; mM range

PMIDs: None found

Sources: GuideToPharmacology

DTC: ADENOSINE TRIPHOSPHATE

Alternate Names: CHEMBL14249 ChEMBL Drug ID

Drug Info:

Publications: Adrián FJ et al., 2006, Allosteric inhibitors of Bcr-abl-dependent cell proliferation., Nat Chem Biol

GuideToPharmacology: 135651446

Alternate Names: ATP GuideToPharmacology Ligand Name

Drug Info:

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Agonist

Endogenous Drug? True

Direct Interaction? False

PMIDs:
None found

Sources:
GuideToPharmacology

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Agonist

Endogenous Drug? True

Direct Interaction? False

PMIDs:
None found

Sources:
GuideToPharmacology

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? True

Direct Interaction? False

PMIDs:
21503959

Sources:
GuideToPharmacology

Interaction Types & Directionality:

activator (activating)

Interaction Info:

Interaction Context cytosolic

Specific Action of the Ligand None

Details of Interaction < mM range

PMIDs:
None found

Sources:
GuideToPharmacology

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? True

PMIDs:
None found

Sources:
GuideToPharmacology

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Agonist

Endogenous Drug? True

PMIDs:
None found

Sources:
GuideToPharmacology

Interaction Types & Directionality:

agonist (activating)

antagonist (inhibitory)

Interaction Info:

Specific Action of the Ligand Agonist

Endogenous Drug? True

Direct Interaction? False

PMIDs:
None found

Sources:
GuideToPharmacology

Interaction Types & Directionality:

blocker (inhibitory)

inhibitor (inhibitory)

Interaction Info:

Specific Action of the Ligand Antagonist

Endogenous Drug? True

PMIDs:
None found

Sources:
GuideToPharmacology

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Agonist

Endogenous Drug? True

Direct Interaction? False

PMIDs:
None found

Sources:
GuideToPharmacology

Interaction Types & Directionality:

agonist (activating)

antagonist (inhibitory)

Interaction Info:

Specific Action of the Ligand Partial agonist

Endogenous Drug? True

Specific Action of the Ligand Antagonist

PMIDs:
None found

Sources:
GuideToPharmacology

Interaction Types & Directionality:

activator (activating)

Interaction Info:

Interaction Context cytosolic

Specific Action of the Ligand None

Details of Interaction endogenous; mM range

PMIDs:
None found

Sources:
GuideToPharmacology

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? True

Direct Interaction? False

PMIDs:
None found

Sources:
GuideToPharmacology

Interaction Types & Directionality:

activator (activating)

Interaction Info:

Interaction Context cytosolic

Specific Action of the Ligand None

Details of Interaction endogenous; mM range

PMIDs:
None found

Sources:
GuideToPharmacology

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Direct Interaction? False

Endogenous Drug? True

Specific Action of the Ligand Agonist

PMIDs:
None found

Sources:
GuideToPharmacology

Interaction Types & Directionality:

inhibitor (inhibitory)

PMIDs:
16415863 11752352 17139284 17016423

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

activator (activating)

Interaction Info:

Interaction Context cytosolic

Specific Action of the Ligand None

Details of Interaction endogenous; mM range

PMIDs:
None found

Sources:
GuideToPharmacology

Alternate Names:

CHEMBL14249 ChEMBL Drug ID

Publications:

Adrián FJ et al., 2006, Allosteric inhibitors of Bcr-abl-dependent cell proliferation., Nat Chem Biol

Alternate Names:

ATP GuideToPharmacology Ligand Name