DGIdb - ADRIAMYCIN Drug Record

ADRIAMYCIN wikidata:Q47520887

Alternate Names:

rxcui:42512

Drug Info:

(0 More Sources)

Publications:

McPherson et al., Selective sensitization of adriamycin-resistant P388 murine leukemia cells to antineoplastic agents following transfection with human DNA topoisomerase II alpha., Anticancer Res.
Xia et al., 2004, [Effects of hypoxia on expression of P-glycoprotein and multidrug resistance protein in human lung adenocarcinoma A549 cell line]., Zhonghua Yi Xue Za Zhi
Segura-Pacheco et al., 2006, Global DNA hypermethylation-associated cancer chemotherapy resistance and its reversion with the demethylating agent hydralazine., J Transl Med
Goeptar et al., 1994, Cytotoxicity of mitomycin C and adriamycin in freshly isolated rat hepatocytes: the role of cytochrome P450., Cancer Res.
Banerjee et al., 1992, Down-regulation of ras and myc expression associated with mdr-1 overexpression in adriamycin-resistant tumor cells., Cell. Mol. Biol.
Ando et al., 2000, Decitabine (5-Aza-2'-deoxycytidine) decreased DNA methylation and expression of MDR-1 gene in K562/ADM cells., Leukemia
Liu et al., 2000, Uncoupling ceramide glycosylation by transfection of glucosylceramide synthase antisense reverses adriamycin resistance., J. Biol. Chem.
Ho et al., 2005, The relative contribution of CHK1 and CHK2 to Adriamycin-induced checkpoint., Exp. Cell Res.
Nakayama et al., 2000, Effect of the lipoprotein lipase activator NO-1886 on adriamycin-induced nephrotic syndrome in rats., Metab. Clin. Exp.
Meng et al., 1999, p53-independent increase in E2F-1 expression enhances the cytotoxic effects of etoposide and of adriamycin., Int. J. Oncol.
Twentyman et al., 1990, Chemosensitisation by verapamil and cyclosporin A in mouse tumour cells expressing different levels of P-glycoprotein and CP22 (sorcin)., Br. J. Cancer
Burchell et al., 1990, The role of xenobiotic glucuronidating enzymes in drug resistance of tumour tissues and cells., Int. Symp. Princess Takamatsu Cancer Res. Fund
Mustonen et al., 1991, Activation of phospholipase A2 by adriamycin in vitro. Role of drug-lipid interactions., J. Biol. Chem.
Koutsilieris et al., 1999, Chemotherapy cytotoxicity of human MCF-7 and MDA-MB 231 breast cancer cells is altered by osteoblast-derived growth factors., Mol. Med.
Deffie et al., 1988, Multifactorial resistance to adriamycin: relationship of DNA repair, glutathione transferase activity, drug efflux, and P-glycoprotein in cloned cell lines of adriamycin-sensitive and -resistant P388 leukemia., Cancer Res.
Joles et al., 1995, Plasma triglyceride levels are higher in nephrotic than in analbuminemic rats despite a similar increase in hepatic triglyceride secretion., Kidney Int.
Thomas et al., Free radical inactivation of rabbit muscle creatinine kinase: catalysis by physiological and hydrolyzed ICRF-187 (ICRF-198) iron chelates., Free Radic. Res.
Barretti et al., 1995, Effects of dietary protein, angiotensin I converting enzyme inhibition and mesangial overload on the progression of adriamycin-induced nephropathy., Braz. J. Med. Biol. Res.
Jazirehi et al., 2001, Adriamycin sensitizes the adriamycin-resistant 8226/Dox40 human multiple myeloma cells to Apo2L/tumor necrosis factor-related apoptosis-inducing ligand-mediated (TRAIL) apoptosis., Clin. Cancer Res.
Morsi et al., 2006, Evaluation of tumour necrosis factor-alpha, soluble P-selectin, gamma-glutamyl transferase, glutathione S-transferase-pi and alpha-fetoprotein in patients with hepatocellular carcinoma before and during chemotherapy., Br. J. Biomed. Sci.

ADRIAMYCIN CKM

Interaction Score: 3.25

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
7834053

Sources:
NCI
ADRIAMYCIN SRI

Interaction Score: 1.63

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
1975203

Sources:
NCI
ADRIAMYCIN UGCG

Interaction Score: 1.63

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10702281

Sources:
NCI
ADRIAMYCIN UGT1A5

Interaction Score: 0.72

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
1966888

Sources:
NCI
ADRIAMYCIN CYP7B1

Interaction Score: 0.65

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
8162589

Sources:
NCI
ADRIAMYCIN AGT

Interaction Score: 0.46

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
7581027

Sources:
NCI
ADRIAMYCIN E2F1

Interaction Score: 0.41

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9863003

Sources:
NCI
ADRIAMYCIN GGT1

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16871999

Sources:
NCI
ADRIAMYCIN LPL

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10831167

Sources:
NCI
ADRIAMYCIN XIAP

Interaction Score: 0.33

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
11751478

Sources:
NCI
ADRIAMYCIN FASN

Interaction Score: 0.31

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
7723242

Sources:
NCI
ADRIAMYCIN PLA2G1B

Interaction Score: 0.3

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
2007582

Sources:
NCI
ADRIAMYCIN DNMT1

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16893460

Sources:
NCI
ADRIAMYCIN CHEK1

Interaction Score: 0.2

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15707569

Sources:
NCI
ADRIAMYCIN TGFB1

Interaction Score: 0.18

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10203574

Sources:
NCI
ADRIAMYCIN GSTP1

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
2897875

Sources:
NCI
ADRIAMYCIN ABCC1

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15130309

Sources:
NCI
ADRIAMYCIN TOP2A

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9494516

Sources:
NCI
ADRIAMYCIN ABCB1

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
1363885 11069027

Sources:
NCI

NCI: ADRIAMYCIN

Version: 14-September-2017

Alternate Names:

C1326 NCI drug code

Drug Info:

Publications:

McPherson et al., Selective sensitization of adriamycin-resistant P388 murine leukemia cells to antineoplastic agents following transfection with human DNA topoisomerase II alpha., Anticancer Res.

Segura-Pacheco et al., 2006, Global DNA hypermethylation-associated cancer chemotherapy resistance and its reversion with the demethylating agent hydralazine., J Transl Med

Goeptar et al., 1994, Cytotoxicity of mitomycin C and adriamycin in freshly isolated rat hepatocytes: the role of cytochrome P450., Cancer Res.

Wikidata: wikidata:Q47520887
- Version: 12-August-2020
Alternate Names:

Drug Info:

Publications:

ADRIAMYCIN Drug Record

ADRIAMYCIN wikidata:Q47520887

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 7834053

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 1975203

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10702281

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 1966888

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 8162589

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 7581027

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9863003

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16871999

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10831167

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 11751478

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 7723242

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 2007582

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16893460

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15707569

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10203574

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 2897875

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15130309

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9494516

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 1363885 11069027

Interaction Types & Directionality:

n/a

PMIDs:
7834053

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
1975203

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
10702281

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
1966888

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
8162589

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
7581027

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
9863003

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
16871999

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
10831167

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
11751478

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
7723242

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
2007582

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
16893460

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15707569

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
10203574

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
2897875

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15130309

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
9494516

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
1363885 11069027

Sources:
NCI

Alternate Names:

C1326 NCI drug code