AFLIBERCEPT Drug Record
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AFLIBERCEPT chembl:CHEMBL1742982 ApprovedAntineoplastic
Alternate Names:
BAY86-5321 BAY-865321 BAY-86-5321 EYLEA AFLIBERCEPT (GENETICAL RECOMBINATION) ZALTRAP VEGF TRAP AVE0005 AVE-0005 ZIV-AFLIBERCEPT AFLIBERCEPT VEGF TRAP-EYE pubchem.compound:124490314 chembl:CHEMBL1742982 chemidplus:862111-32-8 drugbank:08885 rxcui:1232150 Drug Info:
FDA Approval Colorectal cancer Drug Class Therapeutic Antibodies FDA Approval not approved Drug Class fusion protein Drug Indications antineoplastic agent
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Interaction Score: 15.46
Interaction Types & Directionality:
antibody (inhibitory) binder Interaction Info:
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Interaction Score: 12.37
Interaction Types & Directionality:
binder inhibitor (inhibitory) Interaction Info:
Mechanism of Interaction Placenta growth factor inhibitor Direct Interaction yes -
Interaction Score: 6.18
Interaction Types & Directionality:
antibody (inhibitory) Interaction Info:
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Interaction Score: 4.12
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Interaction Score: 2.28
Interaction Types & Directionality:
antibody (inhibitory) binder inhibitor (inhibitory) Interaction Info:
Mechanism of Interaction Vascular endothelial growth factor A inhibitor Direct Interaction yes Trial Name AVE-0005
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- Version: 20-Jun-2017
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ZIV-AFLIBERCEPT Generic Name ZALTRAP Trade Name Drug Info:
Drug Class Therapeutic Antibodies FDA Approval Colorectal cancer Publications:
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- Version: January-2014
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Drug Indications antineoplastic agent Drug Class fusion protein FDA Approval not approved Publications:
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- Version: 18-August-2020
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- Version: 2020.06.01
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D0C9ET TTD Drug ID Drug Info:
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- Version: ChEMBL_27
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- Version: chembl_23
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