DGIdb - AMOXICILLIN Drug Record

AMOXICILLIN chembl:CHEMBL1082 Approved

Alternate Names:

WYMOX
AMOXIDENT 250
AMOXYMED
AQUACIL
AMOXICILLIN
BRL-2333
SUMOX
AMOXI-TABS
AMOXIDENT 500
BIOMOX
AMOXIL
RESPILLIN
FLEMOXIN SOLUTAB
AMIX 250
NSC-277174
AMOXYCILLIN
AMOXICILLIN TRIHYDRATE
ROBAMOX
VETREMOX
GALENAMOX
AMIX 500
AMORAM
AMOXI-INJECT
UTIMOX
AMOXIL FIZTAB
AMOXICILLINE
AMOPEN
POLYMOX
ZOXYCIL 250
TRIMOX
MOXATAG
ZOXYCIL 500
DEDOXIL
AMIX 125
AMRIT
AMOXICILLIN HYDRATE
LAROTID
AMOXIL SF
DISPERMOX
AMOXICILLIN PEDIATRIC
6-(P-HYDROXY-Α-AMINOPHENYLACETAMIDO)PENICILLANIC ACID
AMOXICILLIN (ANHYDROUS)
AMOX
AMOXYCILLIN ANHYDROUS
AMOXICILLINUM
ALPHA-AMINO-P-HYDROXYBENZYLPENICILLIN
(2S,5R,6R)-6-{[(2R)-2-AMINO-2-(4-HYDROXYPHENYL)ACETYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID
AMOPENIXIN
AMOXYCILIN
CLAMOXYL
AMOXICILINA
AMPC
AX
6-(P-HYDROXY-ALPHA-AMINOPHENYLACETAMIDO)PENICILLANIC ACID
AMOLIN
AMOXICILLIN ANHYDROUS
MOXAL
P-HYDROXYAMPICILLIN
Α-AMINO-P-HYDROXYBENZYLPENICILLIN
rxcui:723
pubchem.compound:33613
chemidplus:26787-78-0
rxcui:1297882
chembl:CHEMBL1082
drugbank:01060

Drug Info:

(1 More Sources)

Publications:

Cirulli ET et al., 2019, A Missense Variant in PTPN22 is a Risk Factor for Drug-induced Liver Injury., Gastroenterology
Hautekeete ML et al., 1999, HLA association of amoxicillin-clavulanate--induced hepatitis., Gastroenterology
Sugimoto et al., 2006, Influences of proinflammatory and anti-inflammatory cytokine polymorphisms on eradication rates of clarithromycin-sensitive strains of Helicobacter pylori by triple therapy., Clin. Pharmacol. Ther.
Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol
Ushiama et al., 2002, Dose-dependent inhibition of CYP3A activity by clarithromycin during Helicobacter pylori eradication therapy assessed by changes in plasma lansoprazole levels and partial cortisol clearance to 6beta-hydroxycortisol., Clin. Pharmacol. Ther.
Donaldson PT et al., 2010, Human leucocyte antigen class II genotype in susceptibility and resistance to co-amoxiclav-induced liver injury., J Hepatol
Romano A et al., 1998, Delayed hypersensitivity to aminopenicillins is related to major histocompatibility complex genes., Ann Allergy Asthma Immunol

AMOXICILLIN HLA-DRB5

Interaction Score: 1.82

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10535882

Sources:
PharmGKB
AMOXICILLIN HLA-DRA

Interaction Score: 1.21

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
30664875

Sources:
PharmGKB
AMOXICILLIN HLA-DQB1

Interaction Score: 0.91

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
30664875 10535882

Sources:
PharmGKB
AMOXICILLIN HLA-C

Interaction Score: 0.61

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
30664875

Sources:
PharmGKB
AMOXICILLIN HLA-A

Interaction Score: 0.48

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9609616

Sources:
PharmGKB
AMOXICILLIN HLA-DRB1

Interaction Score: 0.47

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
30664875 20800921 10535882

Sources:
PharmGKB
AMOXICILLIN IL10

Interaction Score: 0.43

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16815316

Sources:
NCI
AMOXICILLIN GSTT1

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
AMOXICILLIN HLA-B

Interaction Score: 0.29

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
30664875

Sources:
PharmGKB
AMOXICILLIN NR1I2

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
AMOXICILLIN POLH

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
AMOXICILLIN CYP2C9

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22931300

Sources:
DTC
AMOXICILLIN CYP3A4

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12152002 22931300

Sources:
DTC NCI
AMOXICILLIN CYP2C19

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22931300

Sources:
DTC
AMOXICILLIN POLK

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
AMOXICILLIN CYP1A2

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22931300

Sources:
DTC
AMOXICILLIN CYP2D6

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22931300

Sources:
DTC

NCI: AMOXICILLIN

Version: 14-September-2017

Alternate Names:

C237 NCI drug code

Drug Info:

Publications:

Ushiama et al., 2002, Dose-dependent inhibition of CYP3A activity by clarithromycin during Helicobacter pylori eradication therapy assessed by changes in plasma lansoprazole levels and partial cortisol clearance to 6beta-hydroxycortisol., Clin. Pharmacol. Ther.

Sugimoto et al., 2006, Influences of proinflammatory and anti-inflammatory cytokine polymorphisms on eradication rates of clarithromycin-sensitive strains of Helicobacter pylori by triple therapy., Clin. Pharmacol. Ther.

DTC: AMOXICILLIN
- Version: 02-September-2020
Alternate Names:

CHEMBL1082 ChEMBL Drug ID

Drug Info:

Publications:

Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol

PharmGKB: amoxicillin

Version: 18-August-2020

Alternate Names:

Drug Info:

Publications:

Cirulli ET et al., 2019, A Missense Variant in PTPN22 is a Risk Factor for Drug-induced Liver Injury., Gastroenterology

Hautekeete ML et al., 1999, HLA association of amoxicillin-clavulanate--induced hepatitis., Gastroenterology

Donaldson PT et al., 2010, Human leucocyte antigen class II genotype in susceptibility and resistance to co-amoxiclav-induced liver injury., J Hepatol

TTD: Amoxicillin
- Version: 2020.06.01
Alternate Names:

D0F6EO TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL1082
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

AMOXICILLIN Drug Record

AMOXICILLIN chembl:CHEMBL1082 Approved

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10535882

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 30664875

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 30664875 10535882

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 30664875

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9609616

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 30664875 20800921 10535882

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16815316

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 30664875

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22931300

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 12152002 22931300

Sources: DTC NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22931300

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22931300

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22931300

Sources: DTC

NCI: AMOXICILLIN

Alternate Names: C237 NCI drug code

Drug Info:

DTC: AMOXICILLIN

Alternate Names: CHEMBL1082 ChEMBL Drug ID

Drug Info:

Publications: Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for &gt;200 compounds., Chem Res Toxicol

Interaction Types & Directionality:

n/a

PMIDs:
10535882

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
30664875

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
30664875 10535882

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
30664875

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
9609616

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
30664875 20800921 10535882

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
16815316

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
30664875

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
22931300

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
12152002 22931300

Sources:
DTC NCI

Interaction Types & Directionality:

n/a

PMIDs:
22931300

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
22931300

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
22931300

Sources:
DTC

Alternate Names:

C237 NCI drug code

Alternate Names:

CHEMBL1082 ChEMBL Drug ID

Publications:

Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol

Alternate Names:

D0F6EO TTD Drug ID