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AMOXICILLIN Drug Record

  • Summary
  • Interactions
  • Claims
  • AMOXICILLIN chembl:CHEMBL1082 Approved

    Alternate Names:

    WYMOX
    AMOXIDENT 250
    AMOXYMED
    AQUACIL
    AMOXICILLIN
    BRL-2333
    SUMOX
    AMOXI-TABS
    AMOXIDENT 500
    BIOMOX
    AMOXIL
    RESPILLIN
    FLEMOXIN SOLUTAB
    AMIX 250
    NSC-277174
    AMOXYCILLIN
    AMOXICILLIN TRIHYDRATE
    ROBAMOX
    VETREMOX
    GALENAMOX
    AMIX 500
    AMORAM
    AMOXI-INJECT
    UTIMOX
    AMOXIL FIZTAB
    AMOXICILLINE
    AMOPEN
    POLYMOX
    ZOXYCIL 250
    TRIMOX
    MOXATAG
    ZOXYCIL 500
    DEDOXIL
    AMIX 125
    AMRIT
    AMOXICILLIN HYDRATE
    LAROTID
    AMOXIL SF
    DISPERMOX
    AMOXICILLIN PEDIATRIC
    6-(P-HYDROXY-Α-AMINOPHENYLACETAMIDO)PENICILLANIC ACID
    AMOXICILLIN (ANHYDROUS)
    AMOX
    AMOXYCILLIN ANHYDROUS
    AMOXICILLINUM
    ALPHA-AMINO-P-HYDROXYBENZYLPENICILLIN
    (2S,5R,6R)-6-{[(2R)-2-AMINO-2-(4-HYDROXYPHENYL)ACETYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID
    AMOPENIXIN
    AMOXYCILIN
    CLAMOXYL
    AMOXICILINA
    AMPC
    AX
    6-(P-HYDROXY-ALPHA-AMINOPHENYLACETAMIDO)PENICILLANIC ACID
    AMOLIN
    AMOXICILLIN ANHYDROUS
    MOXAL
    P-HYDROXYAMPICILLIN
    Α-AMINO-P-HYDROXYBENZYLPENICILLIN
    rxcui:723
    pubchem.compound:33613
    chemidplus:26787-78-0
    rxcui:1297882
    chembl:CHEMBL1082
    drugbank:01060

    Drug Info:

    (1 More Sources)

    Publications:

    Cirulli ET et al., 2019, A Missense Variant in PTPN22 is a Risk Factor for Drug-induced Liver Injury., Gastroenterology
    Hautekeete ML et al., 1999, HLA association of amoxicillin-clavulanate--induced hepatitis., Gastroenterology
    Sugimoto et al., 2006, Influences of proinflammatory and anti-inflammatory cytokine polymorphisms on eradication rates of clarithromycin-sensitive strains of Helicobacter pylori by triple therapy., Clin. Pharmacol. Ther.
    Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol
    Ushiama et al., 2002, Dose-dependent inhibition of CYP3A activity by clarithromycin during Helicobacter pylori eradication therapy assessed by changes in plasma lansoprazole levels and partial cortisol clearance to 6beta-hydroxycortisol., Clin. Pharmacol. Ther.
    Donaldson PT et al., 2010, Human leucocyte antigen class II genotype in susceptibility and resistance to co-amoxiclav-induced liver injury., J Hepatol
    Romano A et al., 1998, Delayed hypersensitivity to aminopenicillins is related to major histocompatibility complex genes., Ann Allergy Asthma Immunol
  • AMOXICILLIN   HLA-DRB5

    Interaction Score: 1.82

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10535882


    Sources:
    PharmGKB

  • AMOXICILLIN   HLA-DRA

    Interaction Score: 1.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    30664875


    Sources:
    PharmGKB

  • AMOXICILLIN   HLA-DQB1

    Interaction Score: 0.91

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    30664875 10535882


    Sources:
    PharmGKB

  • AMOXICILLIN   HLA-C

    Interaction Score: 0.61

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    30664875


    Sources:
    PharmGKB

  • AMOXICILLIN   HLA-A

    Interaction Score: 0.48

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9609616


    Sources:
    PharmGKB

  • AMOXICILLIN   HLA-DRB1

    Interaction Score: 0.47

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    30664875 20800921 10535882


    Sources:
    PharmGKB

  • AMOXICILLIN   IL10

    Interaction Score: 0.43

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16815316


    Sources:
    NCI

  • AMOXICILLIN   GSTT1

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • AMOXICILLIN   HLA-B

    Interaction Score: 0.29

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    30664875


    Sources:
    PharmGKB

  • AMOXICILLIN   NR1I2

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • AMOXICILLIN   POLH

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • AMOXICILLIN   CYP2C9

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • AMOXICILLIN   CYP3A4

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12152002 22931300


    Sources:
    DTC NCI

  • AMOXICILLIN   CYP2C19

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • AMOXICILLIN   POLK

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • AMOXICILLIN   CYP1A2

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • AMOXICILLIN   CYP2D6

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • NCI: AMOXICILLIN

    • Version: 14-September-2017

    Alternate Names:
    C237 NCI drug code

    Drug Info:

    Publications:
    Ushiama et al., 2002, Dose-dependent inhibition of CYP3A activity by clarithromycin during Helicobacter pylori eradication therapy assessed by changes in plasma lansoprazole levels and partial cortisol clearance to 6beta-hydroxycortisol., Clin. Pharmacol. Ther.
    Sugimoto et al., 2006, Influences of proinflammatory and anti-inflammatory cytokine polymorphisms on eradication rates of clarithromycin-sensitive strains of Helicobacter pylori by triple therapy., Clin. Pharmacol. Ther.

  • DTC: AMOXICILLIN

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL1082 ChEMBL Drug ID

    Drug Info:

    Publications:
    Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol

  • PharmGKB: amoxicillin

    • Version: 18-August-2020

    Alternate Names:

    Drug Info:

    Publications:
    Cirulli ET et al., 2019, A Missense Variant in PTPN22 is a Risk Factor for Drug-induced Liver Injury., Gastroenterology
    Hautekeete ML et al., 1999, HLA association of amoxicillin-clavulanate--induced hepatitis., Gastroenterology
    Donaldson PT et al., 2010, Human leucocyte antigen class II genotype in susceptibility and resistance to co-amoxiclav-induced liver injury., J Hepatol

  • TTD: Amoxicillin

    • Version: 2020.06.01

    Alternate Names:
    D0F6EO TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL1082

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

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A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21