DGIdb - ANDROSTANOLONE Drug Record

ANDROSTANOLONE wikidata:Q31686490

Alternate Names:

DHT
ANDRACTIM
STANOLONE
DIHYDROTESTOSTERONE

Drug Info:

(0 More Sources)

Publications:

Gupta et al., 1991, Androgen-estrogen synergy in the regulation of energy metabolism in epididymis and vas deferens of rhesus monkey., Endocr. Res.
Singh et al., 2000, Castration increases and androgens decrease nitric oxide synthase activity in the brain: physiologic implications., Proc. Natl. Acad. Sci. U.S.A.
Kwack et al., 2008, Dihydrotestosterone-inducible dickkopf 1 from balding dermal papilla cells causes apoptosis in follicular keratinocytes., J. Invest. Dermatol.
Angelucci et al., Apoptosis-related gene expression affected by a GnRH analogue without induction of programmed cell death in LNCaP cells., Anticancer Res.
Wilson, 2003, A double life: academic physician and androgen physiologist., Annu. Rev. Physiol.
Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
Askew et al., 2007, Modulation of androgen receptor activation function 2 by testosterone and dihydrotestosterone., J. Biol. Chem.
Rogers et al., 2007, Effect of sex hormones on renal estrogen and angiotensin type 1 receptors in female and male rats., Am. J. Physiol. Regul. Integr. Comp. Physiol.
Uemura et al., 2006, Renin-angiotensin system is an important factor in hormone refractory prostate cancer., Prostate
Shen et al., 2000, Effects of androgen and ageing on gene expression of vasoactive intestinal polypeptide in rat corpus cavernosum., BJU Int.
Singh et al., 2003, Androgens stimulate myogenic differentiation and inhibit adipogenesis in C3H 10T1/2 pluripotent cells through an androgen receptor-mediated pathway., Endocrinology
Sheflin et al., 2001, Androgen regulates the level and subcellular distribution of the AU-rich ribonucleic acid-binding protein HuR both in vitro and in vivo., Endocrinology
Iacopino et al., 2006, Leuprorelin acetate affects ERK1/2 activity in prostate cancer cells., Int. J. Oncol.
Puliyanda et al., 2003, Calpain-mediated AQP2 proteolysis in inner medullary collecting duct., Biochem. Biophys. Res. Commun.
Lustig et al., 1994, An in vitro model for the effects of androgen on neurons employing androgen receptor-transfected PC12 cells., Mol. Cell. Neurosci.
Ormandy et al., 1992, Androgen regulation of prolactin-receptor gene expression in MCF-7 and MDA-MB-453 human breast cancer cells., Int. J. Cancer
Slee et al., 2001, Differentiation-dependent expression of connective tissue growth factor and lysyl oxidase messenger ribonucleic acids in rat granulosa cells., Endocrinology
Leman et al., 2003, Effects of 1,25-dihydroxyvitamin D3 on the distribution of androgen and vitamin D receptors in human prostate neonatal epithelial cells., J. Cell. Biochem.
Tsihlias et al., 2000, Involvement of p27Kip1 in G1 arrest by high dose 5 alpha-dihydrotestosterone in LNCaP human prostate cancer cells., Oncogene
Mason et al., 1997, Effects of dihydrotestosterone on bone biochemical markers in sham and oophorectomized rats., J. Bone Miner. Res.
Vandenput et al., 2002, Evidence from the aged orchidectomized male rat model that 17beta-estradiol is a more effective bone-sparing and anabolic agent than 5alpha-dihydrotestosterone., J. Bone Miner. Res.
Gruber et al., BMP-6-induced osteogenic differentiation of mesenchymal cell lines is not modulated by sex steroids and resveratrol., Cytokine
Le et al., 2006, DHT and testosterone, but not DHEA or E2, differentially modulate IGF-I, IGFBP-2, and IGFBP-3 in human prostatic stromal cells., Am. J. Physiol. Endocrinol. Metab.
Owasoyo, 1983, Effects of orchidectomy and dihydrotestosterone on the choline acetyltransferase activity of specific rat brain areas., Gen. Pharmacol.
Drici et al., 1996, Sex hormones prolong the QT interval and downregulate potassium channel expression in the rabbit heart., Circulation
Pelletier, 2002, Effects of estradiol on prostate epithelial cells in the castrated rat., J. Histochem. Cytochem.
Oliveira et al., 2005, Aquaporin-1 and -9 are differentially regulated by oestrogen in the efferent ductule epithelium and initial segment of the epididymis., Biol. Cell
Wright et al., 1996, Upregulation of prostate-specific membrane antigen after androgen-deprivation therapy., Urology

ANDROSTANOLONE IGFBP5

Interaction Score: 5.38

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16368782

Sources:
NCI
ANDROSTANOLONE PEBP1

Interaction Score: 2.69

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12417618

Sources:
NCI
ANDROSTANOLONE ELAVL1

Interaction Score: 2.69

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
11356683

Sources:
NCI
ANDROSTANOLONE PRLR

Interaction Score: 1.79

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
1544711

Sources:
NCI
ANDROSTANOLONE CAST

Interaction Score: 1.34

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12646165

Sources:
NCI
ANDROSTANOLONE AQP9

Interaction Score: 1.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15850448

Sources:
NCI
ANDROSTANOLONE ME3

Interaction Score: 1.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
1811987

Sources:
NCI
ANDROSTANOLONE DKK1

Interaction Score: 0.9

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17657240

Sources:
NCI
ANDROSTANOLONE VIP

Interaction Score: 0.77

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10886097

Sources:
NCI
ANDROSTANOLONE MYOD1

Interaction Score: 0.6

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12960001

Sources:
NCI
ANDROSTANOLONE CHAT

Interaction Score: 0.54

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
6873629

Sources:
NCI
ANDROSTANOLONE FOLH1

Interaction Score: 0.49

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
8753752

Sources:
NCI
ANDROSTANOLONE KCNA5

Interaction Score: 0.49

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
8823008

Sources:
NCI
ANDROSTANOLONE BGLAP

Interaction Score: 0.47

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9286759 12412816 12967649

Sources:
NCI
ANDROSTANOLONE CCN2

Interaction Score: 0.28

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
11181522

Sources:
NCI
ANDROSTANOLONE AGTR1

Interaction Score: 0.16

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16990489 16482568

Sources:
NCI
ANDROSTANOLONE NOS1

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10725371

Sources:
NCI
ANDROSTANOLONE MAPK3

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16773205

Sources:
NCI
ANDROSTANOLONE BAX

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15517879

Sources:
NCI
ANDROSTANOLONE NTRK1

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
7704433

Sources:
NCI
ANDROSTANOLONE CDK2

Interaction Score: 0.09

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10698512

Sources:
NCI
ANDROSTANOLONE AR

Interaction Score: 0.02

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

PMIDs:
12500968 10592235 17591767

Sources:
NCI TTD
ANDROSTANOLONE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12532336

Sources:
NCI

NCI: DIHYDROTESTOSTERONE

Version: 14-September-2017

Alternate Names:

C29619 NCI drug code

C29618 NCI drug code

Drug Info:

Publications:

Owasoyo, 1983, Effects of orchidectomy and dihydrotestosterone on the choline acetyltransferase activity of specific rat brain areas., Gen. Pharmacol.

Drici et al., 1996, Sex hormones prolong the QT interval and downregulate potassium channel expression in the rabbit heart., Circulation

Wright et al., 1996, Upregulation of prostate-specific membrane antigen after androgen-deprivation therapy., Urology

NCI: DHT

Version: 14-September-2017

Alternate Names:

C29618 NCI drug code

C29619 NCI drug code

Drug Info:

Publications:

Gupta et al., 1991, Androgen-estrogen synergy in the regulation of energy metabolism in epididymis and vas deferens of rhesus monkey., Endocr. Res.

Lustig et al., 1994, An in vitro model for the effects of androgen on neurons employing androgen receptor-transfected PC12 cells., Mol. Cell. Neurosci.

Slee et al., 2001, Differentiation-dependent expression of connective tissue growth factor and lysyl oxidase messenger ribonucleic acids in rat granulosa cells., Endocrinology

TTD: Dihydrotestosterone
- Version: 2020.06.01
Alternate Names:

D04DJN TTD Drug ID

Drug Info:

Publications:
Wikidata: wikidata:Q31686490
- Version: 12-August-2020
Alternate Names:

Drug Info:

Publications:

ANDROSTANOLONE Drug Record

ANDROSTANOLONE wikidata:Q31686490

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16368782

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 12417618

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 11356683

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 1544711

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 12646165

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15850448

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 1811987

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 17657240

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10886097

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 12960001

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 6873629

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 8753752

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 8823008

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9286759 12412816 12967649

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 11181522

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16990489 16482568

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10725371

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16773205

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15517879

Interaction Types & Directionality:

n/a

PMIDs:
16368782

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
12417618

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
11356683

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
1544711

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
12646165

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15850448

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
1811987

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
17657240

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
10886097

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
12960001

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
6873629

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
8753752

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
8823008

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
9286759 12412816 12967649

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
11181522

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
16990489 16482568

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
10725371

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
16773205

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15517879

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
7704433

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
10698512

Sources:
NCI

Interaction Types & Directionality:

agonist (activating)

PMIDs:
12500968 10592235 17591767

Sources:
NCI TTD

Interaction Types & Directionality:

n/a

PMIDs:
12532336

Sources:
NCI

Alternate Names:

C29619 NCI drug code

C29618 NCI drug code

Alternate Names:

C29618 NCI drug code

C29619 NCI drug code

Alternate Names:

D04DJN TTD Drug ID