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AZITHROMYCIN Drug Record

  • Summary
  • Interactions
  • Claims
  • AZITHROMYCIN chembl:CHEMBL529 Approved

    Alternate Names:

    SUNAMED
    XZ 405
    AZASITE
    AZYTER
    AZITHROMYCIN
    SUMAMED
    ZMAX
    XZ-450
    CLAMELLE
    CP 62993
    XZ 450
    AZITHROMYCIN DIHYDRATE
    AZITHROMYCIN HYDRATE
    ZITHROMAX
    CP-62993
    AZITHROMYCIN ANHYDROUS
    AZITHROMYCINE
    CP-62,993
    AZITHROMYCINUM
    AZENIL
    AZIMAKROL
    AZITROMICINA
    AZITROMIN
    HEMOMYCIN
    AZIGRAM
    AZIFAST
    rxcui:1299904
    chembl:CHEMBL529
    rxcui:18631
    drugbank:00207
    pubchem.compound:447043
    chemidplus:83905-01-5

    Drug Info:

    (0 More Sources)

    Publications:

    Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol
    Ollivier et al., 2005, Modulation of tissue factor expression by rapamycin and FK-506 in lipopolysaccharide-stimulated human mononuclear cells and serum-stimulated aortic smooth muscle cells., Thromb. Haemost.
    Aktan et al., Effect of macrolide antibiotics on nitric oxide synthase and xanthine oxidase activities, and malondialdehyde level in erythrocyte of the guinea pigs with experimental otitis media with effusion., Pol J Pharmacol
    Seral et al., 2003, Influence of P-glycoprotein and MRP efflux pump inhibitors on the intracellular activity of azithromycin and ciprofloxacin in macrophages infected by Listeria monocytogenes or Staphylococcus aureus., J. Antimicrob. Chemother.
  • AZITHROMYCIN   TFPI

    Interaction Score: 1.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16113783


    Sources:
    NCI

  • AZITHROMYCIN   XDH

    Interaction Score: 0.65

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    14730107


    Sources:
    NCI

  • AZITHROMYCIN   NOS1

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    14730107


    Sources:
    NCI

  • AZITHROMYCIN   ABCC1

    Interaction Score: 0.27

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12697643


    Sources:
    NCI

  • AZITHROMYCIN   CYP2C9

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • AZITHROMYCIN   CYP2C19

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • AZITHROMYCIN   CYP1A2

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • AZITHROMYCIN   CYP2D6

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • AZITHROMYCIN   CYP3A4

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • DTC: AZITHROMYCIN

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL529 ChEMBL Drug ID

    Drug Info:

    Publications:
    Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol

  • NCI: AZITHROMYCIN

    • Version: 14-September-2017

    Alternate Names:
    C28844 NCI drug code

    Drug Info:

    Publications:
    Seral et al., 2003, Influence of P-glycoprotein and MRP efflux pump inhibitors on the intracellular activity of azithromycin and ciprofloxacin in macrophages infected by Listeria monocytogenes or Staphylococcus aureus., J. Antimicrob. Chemother.
    Aktan et al., Effect of macrolide antibiotics on nitric oxide synthase and xanthine oxidase activities, and malondialdehyde level in erythrocyte of the guinea pigs with experimental otitis media with effusion., Pol J Pharmacol
    Ollivier et al., 2005, Modulation of tissue factor expression by rapamycin and FK-506 in lipopolysaccharide-stimulated human mononuclear cells and serum-stimulated aortic smooth muscle cells., Thromb. Haemost.

  • ChemblDrugs: chembl:CHEMBL529

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21