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BAFETINIB Drug Record

  • Summary
  • Interactions
  • Claims
  • BAFETINIB chembl:CHEMBL206834 Antineoplastic

    Alternate Names:

    NS-187
    INNO-406
    CNS-9
    BAFETINIB

    Drug Info:

    Drug Class Kinase Inhibitors
    (1 More Sources)

    Publications:

    Deguchi Y et al., 2008, Comparison of imatinib, dasatinib, nilotinib and INNO-406 in imatinib-resistant cell lines., Leuk Res
    Ishibashi T et al., 2016, Ph-like ALL-related novel fusion kinase ATF7IP-PDGFRB exhibits high sensitivity to tyrosine kinase inhibitors in murine cells., Exp Hematol
  • BAFETINIB   LYN

    Interaction Score: 1.16

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Tyrosine-protein kinase Lyn inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    MyCancerGenome ChemblInteractions TTD

  • BAFETINIB   ABL1

    Interaction Score: 0.95

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Tyrosine-protein kinase ABL inhibitor
    Direct Interaction yes

    PMIDs:
    18191450


    Sources:
    MyCancerGenome ChemblInteractions CIViC

  • BAFETINIB   PDGFRB

    Interaction Score: 0.44

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    26703895


    Sources:
    CIViC

  • BAFETINIB   ABCB1

    Interaction Score: 0.13

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18191450


    Sources:
    CIViC

  • MyCancerGenome: BAFETINIB

    • Version: 20-Jun-2017

    Alternate Names:
    INNO-406 Development Name
    NS-187 Development Name
    BAFETINIB Generic Name

    Drug Info:
    Drug Class Kinase Inhibitors

    Publications:

  • CIViC: BAFETINIB

    • Version: 14-September-2020

    Alternate Names:

    Drug Info:

    Publications:
    Deguchi Y et al., 2008, Comparison of imatinib, dasatinib, nilotinib and INNO-406 in imatinib-resistant cell lines., Leuk Res
    Ishibashi T et al., 2016, Ph-like ALL-related novel fusion kinase ATF7IP-PDGFRB exhibits high sensitivity to tyrosine kinase inhibitors in murine cells., Exp Hematol

  • TTD: Bafetinib

    • Version: 2020.06.01

    Alternate Names:
    D0G0VV TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL206834

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

  • ChemblInteractions: CHEMBL206834

    • Version: chembl_23

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21