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BETAXOLOL Drug Record

  • Summary
  • Interactions
  • Claims
  • BETAXOLOL chembl:CHEMBL423 Approved

    Alternate Names:

    BETAXOLOL
    KERLONE
    SL-7521210 FREE BASE
    ALO-140102 FREE BASE
    BETOPTIC SUSP
    BETOPTIC
    KERLEDEX
    1-(ISOPROPYLAMINO)-3-[P-(CYCLOPROPYLMETHOXYETHYL)PHENOXY]-2-PROPANOL
    BETAXOLOL HCL
    SL-75212-10
    BETAXOLOLUM
    KERLONE®
    1-(4-(2-(CYCLOPROPYLMETHOXY)ETHYL)PHENOXY)-3-((1-METHYLETHYL)AMINO)-2-PROPANOL
    BETOPTIC®
    chemidplus:63659-18-7
    pubchem.compound:2369
    rxcui:1520
    drugbank:00195
    chembl:CHEMBL423

    Drug Info:

    Drug Class antihypertensive agents
    Year of Approval 1985
    FDA Approval 1985
    Drug Class small molecule
    Drug Indications Antihypertensive Agents
    (1 More Sources)

    Publications:

    el Tayar N et al., 1988, Modeling of beta-adrenoceptors based on molecular electrostatic potential studies of agonists and antagonists., J Med Chem
    Lesar, 1987, Comparison of ophthalmic beta-blocking agents., Clin Pharm
    Rudoy et al., 2007, Betaxolol, a selective beta(1)-adrenergic receptor antagonist, diminishes anxiety-like behavior during early withdrawal from chronic cocaine administration in rats., Prog. Neuropsychopharmacol. Biol. Psychiatry
    Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
    Satoh et al., 1990, Effects of betaxolol on cardiohemodynamics and coronary circulation in anesthetized dogs: comparison with atenolol and propranolol., Jpn. J. Pharmacol.
    McLean et al., 2002, Generation and analysis of constitutively active and physically destabilized mutants of the human beta(1)-adrenoceptor., Mol. Pharmacol.
  • BETAXOLOL   ADRB1

    Interaction Score: 7.45

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    2903243 2891463 17513029 11752352 2077180 12181453


    Sources:
    DTC TdgClinicalTrial TEND TTD

  • TEND: BETAXOLOL

    • Version: 01-August-2011

    Alternate Names:
    BETAXOLOL Primary Drug Name

    Drug Info:
    Year of Approval 1985
    Drug Class antihypertensive agents

    Publications:

  • TdgClinicalTrial: BETAXOLOL

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications Antihypertensive Agents
    Drug Class small molecule
    FDA Approval 1985

    Publications:

  • DTC: BETAXOLOL

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL423 ChEMBL Drug ID

    Drug Info:

    Publications:
    el Tayar N et al., 1988, Modeling of beta-adrenoceptors based on molecular electrostatic potential studies of agonists and antagonists., J Med Chem

  • TTD: Betaxolol

    • Version: 2020.06.01

    Alternate Names:
    D03ROX TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL423

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

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A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21