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BISINDOLYLMALEIMIDE IX Drug Record

  • Summary
  • Interactions
  • Claims
  • BISINDOLYLMALEIMIDE IX chembl:CHEMBL6291

    Alternate Names:

    RO-318220

    Drug Info:

    (0 More Sources)

    Publications:

    Abdel-Halim M et al., 2014, Discovery and optimization of 1,3,5-trisubstituted pyrazolines as potent and highly selective allosteric inhibitors of protein kinase C-ζ., J Med Chem
    Trapp J et al., 2006, Adenosine mimetics as inhibitors of NAD+-dependent histone deacetylases, from kinase to sirtuin inhibition., J Med Chem
    Huber K et al., 2010, Novel 3-arylideneindolin-2-ones as inhibitors of NAD+ -dependent histone deacetylases (sirtuins)., J Med Chem
  • BISINDOLYLMALEIMIDE IX   SIRT2

    Interaction Score: 2.9

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17149860 20030343


    Sources:
    DTC

  • BISINDOLYLMALEIMIDE IX   PRKCB

    Interaction Score: 1.19

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25058929


    Sources:
    DTC

  • BISINDOLYLMALEIMIDE IX   ALOX15

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • BISINDOLYLMALEIMIDE IX   MAPK1

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • BISINDOLYLMALEIMIDE IX   POLI

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • BISINDOLYLMALEIMIDE IX   SMAD3

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • BISINDOLYLMALEIMIDE IX   MAPT

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • BISINDOLYLMALEIMIDE IX   EHMT2

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • DTC: BISINDOLYLMALEIMIDE IX

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL6291 ChEMBL Drug ID

    Drug Info:

    Publications:
    Abdel-Halim M et al., 2014, Discovery and optimization of 1,3,5-trisubstituted pyrazolines as potent and highly selective allosteric inhibitors of protein kinase C-ζ., J Med Chem
    Huber K et al., 2010, Novel 3-arylideneindolin-2-ones as inhibitors of NAD+ -dependent histone deacetylases (sirtuins)., J Med Chem
    Trapp J et al., 2006, Adenosine mimetics as inhibitors of NAD+-dependent histone deacetylases, from kinase to sirtuin inhibition., J Med Chem

  • DTC: RO-318220

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL1591531 ChEMBL Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL6291

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21