• Interaction Score: 3.91

    Interaction Types & Directionality:
    activator (activating)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction T cell surface glycoprotein CD3 cross-linking agent
    Trial Name MT-103

  • Interaction Score: 3.51

    Interaction Types & Directionality:
    activator (activating)
    antibody (inhibitory)

    Interaction Info:
    Mechanism of Interaction B-lymphocyte antigen CD19 cross-linking agent
    Direct Interaction yes
    Trial Name MT-103

  • Interaction Score: 3.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name MT-103
    Novel drug target Established target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • Interaction Score: 2.73

    Interaction Types & Directionality:
    antibody (inhibitory)

    Interaction Info:
    Mechanism of Interaction T cell surface glycoprotein CD3 cross-linking agent
    Direct Interaction yes
    Details of the Assay for Interaction Binding of the single-chain Fv portion of blinatumomab to CD3.

  • Interaction Score: 1.52

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Fusion protein BCR:ABL1

    PMIDs:
    None found


    Sources:
    PharmGKB FDA

  • Interaction Score: 1.4

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name MT-103
    Novel drug target Established target
    Mechanism of Interaction T cell surface glycoprotein CD3 cross-linking agent

    PMIDs:
    None found


  • Interaction Score: 0.26

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Fusion protein BCR:ABL1

    PMIDs:
    None found


    Sources:
    PharmGKB FDA