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BUTETHAL Drug Record

  • Summary
  • Interactions
  • Claims
  • BUTETHAL chembl:CHEMBL404422 Approved

    Alternate Names:

    BUTOBARBITAL
    BUTOBARBITONE
    NEONAL
    BUTETHAL
    SONERYL
    drugbank:01353
    chembl:CHEMBL404422
    chemidplus:77-28-1
    rxcui:19874
    pubchem.compound:6473

    Drug Info:

    Drug Class hypnotics and sedatives
    Year of Approval not approved by the fda
    Drug Categories barbiturates, plain
    FDA Approval not approved by the FDA
    Drug Class small molecule
    Drug Indications Hypnotics and Sedatives
    Drug Categories anticholinergic agents
    Drug Categories nicotinic antagonists
    (1 More Sources)

    Publications:

    Yamakura et al., 2001, Anesthetics and ion channels: molecular models and sites of action., Annu. Rev. Pharmacol. Toxicol.
    Mehta et al., 1999, An update on GABAA receptors., Brain Res. Brain Res. Rev.
    Arias et al., 2005, Anesthetics as chemical tools to study the structure and function of nicotinic acetylcholine receptors., Curr. Protein Pept. Sci.
    Krasowski et al., 1999, General anaesthetic actions on ligand-gated ion channels., Cell. Mol. Life Sci.
    Whiting, 2003, The GABAA receptor gene family: new opportunities for drug development., Curr Opin Drug Discov Devel
    Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
    Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
    Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
  • BUTETHAL   GRIK2

    Interaction Score: 1.29

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    11264449 10487207


    Sources:
    TEND TdgClinicalTrial DrugBank

  • BUTETHAL   CHRNA4

    Interaction Score: 0.6

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    11264449 16248797 10487207


    Sources:
    TEND TdgClinicalTrial DrugBank

  • BUTETHAL   GRIA2

    Interaction Score: 0.58

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    11264449 10487207


    Sources:
    TEND TdgClinicalTrial DrugBank

  • BUTETHAL   CHRNA7

    Interaction Score: 0.52

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    11264449 16248797 10487207


    Sources:
    TEND TdgClinicalTrial DrugBank

  • BUTETHAL   GABRA1

    Interaction Score: 0.48

    Interaction Types & Directionality:
    potentiator

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    14579514 11264449 11752352 17139284 10209232 17016423 10487207


    Sources:
    TEND TdgClinicalTrial TTD DrugBank

  • BUTETHAL   GABRA6

    Interaction Score: 0.36

    Interaction Types & Directionality:
    potentiator

    Interaction Info:
    Novel drug target Established target
    Trial Name -

    PMIDs:
    11264449 10209232


    Sources:
    TEND TdgClinicalTrial DrugBank

  • BUTETHAL   GABRA5

    Interaction Score: 0.33

    Interaction Types & Directionality:
    potentiator

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    11264449 10209232


    Sources:
    TEND TdgClinicalTrial DrugBank

  • BUTETHAL   GABRA2

    Interaction Score: 0.32

    Interaction Types & Directionality:
    potentiator

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    11264449 10209232


    Sources:
    TEND TdgClinicalTrial DrugBank

  • BUTETHAL   GABRA3

    Interaction Score: 0.32

    Interaction Types & Directionality:
    potentiator

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    11264449 10209232


    Sources:
    TEND TdgClinicalTrial DrugBank

  • BUTETHAL   GABRA4

    Interaction Score: 0.29

    Interaction Types & Directionality:
    potentiator

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    10209232


    Sources:
    TEND TdgClinicalTrial DrugBank

  • DrugBank: DB01353

    • Version: 5.1.7

    Alternate Names:
    BUTOBARBITAL DrugBank Drug Name
    77-28-1 CAS Number
    Neonal Drug Brand

    Drug Info:
    Drug Type small molecule
    Drug Groups approved
    Drug Groups illicit

    Publications:
    Yamakura et al., 2001, Anesthetics and ion channels: molecular models and sites of action., Annu. Rev. Pharmacol. Toxicol.
    Mehta et al., 1999, An update on GABAA receptors., Brain Res. Brain Res. Rev.
    Whiting, 2003, The GABAA receptor gene family: new opportunities for drug development., Curr Opin Drug Discov Devel

  • TEND: BUTETHAL

    • Version: 01-August-2011

    Alternate Names:
    BUTETHAL Primary Drug Name

    Drug Info:
    Year of Approval not approved by the fda
    Drug Class hypnotics and sedatives

    Publications:

  • TdgClinicalTrial: BUTETHAL

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications Hypnotics and Sedatives
    Drug Class small molecule
    FDA Approval not approved by the FDA

    Publications:

  • TTD: Butethal

    • Version: 2020.06.01

    Alternate Names:
    D0O3AB TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL404422

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

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A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21