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CEFTRIAXONE Drug Record

  • Summary
  • Interactions
  • Claims
  • CEFTRIAXONE chembl:CHEMBL161 Approved

    Alternate Names:

    CEFTRIAXONE
    ROCEPHIN
    (6R,7R)-7-{[(2Z)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-(METHOXYIMINO)ACETYL]AMINO}-3-{[(2-METHYL-5,6-DIOXO-1,2,5,6-TETRAHYDRO-1,2,4-TRIAZIN-3-YL)SULFANYL]METHYL}-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACID
    CEFTRIAXONA
    ROCEPHIN®
    FIDATO
    CEFTRIAXONUM
    CEFATRIAXONE
    C18H18N8O7S3
    CEFTRIAZONE
    chembl:CHEMBL161
    drugbank:01212
    chemidplus:73384-59-5
    rxcui:2193
    pubchem.compound:5479530

    Drug Info:

    (2 More Sources)

    Publications:

    Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol
    Allegra S et al., 2018, Effect of ABCC2 and ABCG2 Gene Polymorphisms and CSF-to-Serum Albumin Ratio on Ceftriaxone Plasma and Cerebrospinal Fluid Concentrations., J Clin Pharmacol
    de Waart DR et al., 2012, Oral availability of cefadroxil depends on ABCC3 and ABCC4., Drug Metab Dispos
    Pacheco et al., 1994, Antibiotics and production of granulocyte-macrophage colony-stimulating factor by human bronchial epithelial cells in vitro. A comparison of cefodizime and ceftriaxone., Arzneimittelforschung
  • CEFTRIAXONE   CYB5R3

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • CEFTRIAXONE   ABCC3

    Interaction Score: 0.41

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22166395


    Sources:
    DTC

  • CEFTRIAXONE   ABCC2

    Interaction Score: 0.39

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    29873816 22166395


    Sources:
    DTC PharmGKB

  • CEFTRIAXONE   ABCC4

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22166395


    Sources:
    DTC

  • CEFTRIAXONE   CXCL8

    Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    8011012


    Sources:
    NCI

  • CEFTRIAXONE   ABCG2

    Interaction Score: 0.17

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    29873816


    Sources:
    PharmGKB

  • CEFTRIAXONE   G6PD

    Interaction Score: 0.15

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB FDA

  • CEFTRIAXONE   CYP2C9

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • CEFTRIAXONE   CYP2C19

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • CEFTRIAXONE   CYP1A2

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • CEFTRIAXONE   CYP2D6

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • CEFTRIAXONE   CYP3A4

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • DTC: CEFTRIAXONE

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL161 ChEMBL Drug ID

    Drug Info:

    Publications:
    Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol
    de Waart DR et al., 2012, Oral availability of cefadroxil depends on ABCC3 and ABCC4., Drug Metab Dispos

  • NCI: CEFTRIAXONE

    • Version: 14-September-2017

    Alternate Names:
    C817 NCI drug code

    Drug Info:

    Publications:
    Pacheco et al., 1994, Antibiotics and production of granulocyte-macrophage colony-stimulating factor by human bronchial epithelial cells in vitro. A comparison of cefodizime and ceftriaxone., Arzneimittelforschung

  • PharmGKB: ceftriaxone

    • Version: 18-August-2020

    Alternate Names:

    Drug Info:

    Publications:
    Allegra S et al., 2018, Effect of ABCC2 and ABCG2 Gene Polymorphisms and CSF-to-Serum Albumin Ratio on Ceftriaxone Plasma and Cerebrospinal Fluid Concentrations., J Clin Pharmacol

  • TTD: Ceftriaxone

    • Version: 2020.06.01

    Alternate Names:
    D07ACT TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL161

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

  • FDA: Ceftriaxone

    • Version: 04-September-2020

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21