• Interaction Score: 9.57

    Interaction Types & Directionality:
    antagonist (inhibitory)
    inhibitor (inhibitory)

    Interaction Info:
    Notes Targets ALPHA-V/BETA-3 INTEGRIN
    Trial Name cilengitide. EMD-121974
    Novel drug target Novel Target

    PMIDs:
    None found


  • Interaction Score: 6.38

    Interaction Types & Directionality:
    antagonist (inhibitory)
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Integrin alpha-V/beta-3 antagonist
    Notes Targets ALPHA-V/BETA-5 INTEGRIN

  • Interaction Score: 4.56

    Interaction Types & Directionality:
    antagonist (inhibitory)
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name cilengitide. EMD-121974
    Novel drug target Established target
    Mechanism of Interaction Integrin alpha-V/beta-3 antagonist

  • Interaction Score: 1.82

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name cilengitide. EMD-121974
    Novel drug target Novel Target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • Interaction Score: 0.58

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12154028


    Sources:
    NCI