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CIPROFLOXACIN Drug Record

  • Summary
  • Interactions
  • Claims
  • CIPROFLOXACIN chembl:CHEMBL8 ApprovedAntineoplastic

    Alternate Names:

    BAY-Q-3939
    BAY O 9867 FREE BASE
    CETRAXAL
    CIPROFLOXACIN
    CIPROBAY
    OTIPRIO
    CILOXAN
    VELMONIT
    BAY-O-9867 FREE BASE
    BAYQ3939
    CIPRO
    CPR867
    1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXO-7-(1-PIPERAZINYL)-3-QUINOLINECARBOXYLIC ACID
    1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID
    1-CYCLOPROPYL-6-FLUORO-4-OXO-7-(PIPERAZIN-1-YL)-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID
    1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID
    1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YLQUINOLINE-3-CARBOXYLIC ACID
    CIPROFLOXACINO
    CIPROFLOXACINUM
    1-CYCLOPROPYL-6-FLUORO-7-HEXAHYDRO-1-PYRAZINYL-4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXYLIC ACID
    CIPROFLOXACINE
    1-CYCLOPROPYL-6-FLUORO-7-(4-METHYL-PIPERAZIN-1-YL)-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID
    drugbank:00537
    rxcui:2551
    chemidplus:85721-33-1
    chembl:CHEMBL8
    pubchem.compound:2764

    Drug Info:

    (0 More Sources)

    Publications:

    Peterson et al., 2004, Role of CYP1A2 and CYP2E1 in the pentoxifylline ciprofloxacin drug interaction., Biochem. Pharmacol.
    Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol
    Šimić I et al., 2016, CYP2D6 *6/*6 genotype and drug interactions as cause of haloperidol-induced extrapyramidal symptoms., Pharmacogenomics
    Aranha et al., 2003, Suppression of human prostate cancer cell growth by ciprofloxacin is associated with cell cycle arrest and apoptosis., Int. J. Oncol.
    Aranha et al., 2000, Ciprofloxacin mediated cell growth inhibition, S/G2-M cell cycle arrest, and apoptosis in a human transitional cell carcinoma of the bladder cell line., Clin. Cancer Res.
    Sansone S et al., 2010, Ciprofloxacin-induced acute haemolytic anaemia in a patient with glucose-6-phosphate dehydrogenase Mediterranean deficiency: a case report., Ann Hematol
  • CIPROFLOXACIN   CYP2E1

    Interaction Score: 0.6

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15194011


    Sources:
    NCI

  • CIPROFLOXACIN   BAX

    Interaction Score: 0.43

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12632069 10741713


    Sources:
    NCI

  • CIPROFLOXACIN   G6PD

    Interaction Score: 0.19

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    20127091


    Sources:
    PharmGKB

  • CIPROFLOXACIN   CYP2D6

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300 27469576


    Sources:
    DTC PharmGKB

  • CIPROFLOXACIN   CYP2C9

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • CIPROFLOXACIN   CYP2C19

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • CIPROFLOXACIN   CYP1A2

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • CIPROFLOXACIN   HSD17B10

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CIPROFLOXACIN   CYP3A4

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • NCI: CIPROFLOXACIN

    • Version: 14-September-2017

    Alternate Names:
    C375 NCI drug code

    Drug Info:

    Publications:
    Peterson et al., 2004, Role of CYP1A2 and CYP2E1 in the pentoxifylline ciprofloxacin drug interaction., Biochem. Pharmacol.
    Aranha et al., 2000, Ciprofloxacin mediated cell growth inhibition, S/G2-M cell cycle arrest, and apoptosis in a human transitional cell carcinoma of the bladder cell line., Clin. Cancer Res.
    Aranha et al., 2003, Suppression of human prostate cancer cell growth by ciprofloxacin is associated with cell cycle arrest and apoptosis., Int. J. Oncol.

  • DTC: CIPROFLOXACIN

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL8 ChEMBL Drug ID

    Drug Info:

    Publications:
    Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol

  • PharmGKB: ciprofloxacin

    • Version: 18-August-2020

    Alternate Names:

    Drug Info:

    Publications:
    Sansone S et al., 2010, Ciprofloxacin-induced acute haemolytic anaemia in a patient with glucose-6-phosphate dehydrogenase Mediterranean deficiency: a case report., Ann Hematol
    Šimić I et al., 2016, CYP2D6 *6/*6 genotype and drug interactions as cause of haloperidol-induced extrapyramidal symptoms., Pharmacogenomics

  • ChemblDrugs: chembl:CHEMBL8

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21