DGIdb - CLENBUTEROL Drug Record

CLENBUTEROL chembl:CHEMBL49080 Approved

Alternate Names:

NAB-365
CLENBUTEROL
CLENBUTEROL HCL

Drug Info:

FDA Approval	not approved by the FDA
Drug Class	small molecule
Drug Indications	Bronchodilator Agents
Year of Approval	not approved by the fda
Drug Class	bronchodilator agents

(1 More Sources)

Publications:

Ryall et al., 2002, Beta 2-agonist fenoterol has greater effects on contractile function of rat skeletal muscles than clenbuterol., Am. J. Physiol. Regul. Integr. Comp. Physiol.
Zhu et al., 2001, Beta(2)-adrenoceptor stimulation enhances latent transforming growth factor-beta-binding protein-1 and transforming growth factor-beta1 expression in rat hippocampus after transient forebrain ischemia., Neuroscience
Choo et al., 1992, Anabolic effects of clenbuterol on skeletal muscle are mediated by beta 2-adrenoceptor activation., Am. J. Physiol.
Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
Sillence et al., 1991, Effects of clenbuterol, ICI118551 and sotalol on the growth of cardiac and skeletal muscle and on beta 2-adrenoceptor density in female rats., Naunyn Schmiedebergs Arch. Pharmacol.
Mazzanti et al., 2007, A pharmacodynamic study on clenbuterol-induced toxicity: beta1- and beta2-adrenoceptors involvement in guinea-pig tachycardia in an in vitro model., Food Chem. Toxicol.
MacDonald ML et al., 2006, Identifying off-target effects and hidden phenotypes of drugs in human cells., Nat Chem Biol

CLENBUTEROL ADRB2

Interaction Score: 5.31

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
12388476 11720783 1322047 11752352 1685013 17449161 16680159

Sources:
DTC TdgClinicalTrial TEND TTD

TdgClinicalTrial: CLENBUTEROL
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications Bronchodilator Agents

Drug Class small molecule

FDA Approval not approved by the FDA

Publications:
TEND: CLENBUTEROL
- Version: 01-August-2011
Alternate Names:

Drug Info:

Drug Class bronchodilator agents

Year of Approval not approved by the fda

Publications:
DTC: CLENBUTEROL
- Version: 02-September-2020
Alternate Names:

CHEMBL49080 ChEMBL Drug ID

Drug Info:

Publications:

MacDonald ML et al., 2006, Identifying off-target effects and hidden phenotypes of drugs in human cells., Nat Chem Biol
TTD: Clenbuterol
- Version: 2020.06.01
Alternate Names:

D0X5NX TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL49080
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

Trial Name	-
Novel drug target	Established target

CLENBUTEROL Drug Record

CLENBUTEROL chembl:CHEMBL49080 Approved

Alternate Names:

Drug Info:

Publications:

CLENBUTEROL ADRB2

Interaction Types & Directionality: agonist (activating)

Interaction Info: Trial Name - Novel drug target Established target

PMIDs: 12388476 11720783 1322047 11752352 1685013 17449161 16680159

Sources: DTC TdgClinicalTrial TEND TTD

TdgClinicalTrial: CLENBUTEROL

Alternate Names:

Drug Info: Drug Indications Bronchodilator Agents Drug Class small molecule FDA Approval not approved by the FDA

Publications:

TEND: CLENBUTEROL

Alternate Names:

Drug Info: Drug Class bronchodilator agents Year of Approval not approved by the fda

Publications:

DTC: CLENBUTEROL

Alternate Names: CHEMBL49080 ChEMBL Drug ID

Drug Info:

Publications: MacDonald ML et al., 2006, Identifying off-target effects and hidden phenotypes of drugs in human cells., Nat Chem Biol

TTD: Clenbuterol

Alternate Names: D0X5NX TTD Drug ID

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL49080

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
12388476 11720783 1322047 11752352 1685013 17449161 16680159

Sources:
DTC TdgClinicalTrial TEND TTD

Drug Info:

Drug Indications Bronchodilator Agents

Drug Class small molecule

FDA Approval not approved by the FDA

Drug Info:

Drug Class bronchodilator agents

Year of Approval not approved by the fda

Alternate Names:

CHEMBL49080 ChEMBL Drug ID

Publications:

MacDonald ML et al., 2006, Identifying off-target effects and hidden phenotypes of drugs in human cells., Nat Chem Biol

Alternate Names:

D0X5NX TTD Drug ID