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CLOTRIMAZOLE Drug Record

  • Summary
  • Interactions
  • Claims
  • CLOTRIMAZOLE chembl:CHEMBL104 Approved

    Alternate Names:

    MYCIL GOLD
    MYCELEX
    PRIVACOM
    CANESTEN CRM COMBI
    BAY-5097
    FUNGEDERM
    GYNE-LOTRIMIN COMBINATION PACK
    CLOTRIMAZOLE
    CANESTEN INTERNAL
    GNF-PF-3499
    GYNE-LOTRIMIN 3
    GYNE-LOTRIMIN
    MYCELEX-G
    ACTAVALL
    GYNE-LOTRIMIN 3 COMBINATION PACK
    MYCELEX-7
    CANESTEN AF
    CANDIDEN
    MASNODERM
    NSC-257473
    GYNIX
    ABTRIM
    TRIMYSTEN
    TRIVAGIZOLE 3
    CANESTEN
    MYCELEX-7 COMBINATION PACK
    CANESTEN VC
    CANESTEN®
    1-(ALPHA-(2-CHLOROPHENYL)BENZHYDRYL)IMIDAZOLE
    LOTRIMIN®
    1-((2-CHLOROPHENYL)DIPHENYLMETHYL)-1H-IMIDAZOLE
    MYCELEX (TN)
    1-(O-CHLOROTRITYL)IMIDAZOLE
    1-(O-CHLORO-ALPHA,ALPHA-DIPHENYLBENZYL)IMIDAZOLE
    1-(Α-(2-CHLOROPHENYL)BENZHYDRYL)IMIDAZOLE
    LOTRIMIN (TN)
    1-(O-CHLORO-Α,Α-DIPHENYLBENZYL)IMIDAZOLE
    chemidplus:23593-75-1
    drugbank:00257
    rxcui:2623
    chembl:CHEMBL104
    pubchem.compound:2812

    Drug Info:

    (0 More Sources)

    Publications:

    Jyrkkärinne J et al., 2008, Insights into ligand-elicited activation of human constitutive androstane receptor based on novel agonists and three-dimensional quantitative structure-activity relationship., J Med Chem
    MacDonald ML et al., 2006, Identifying off-target effects and hidden phenotypes of drugs in human cells., Nat Chem Biol
    Faucette et al., 2004, Regulation of CYP2B6 in primary human hepatocytes by prototypical inducers., Drug Metab. Dispos.
    Dring AM et al., 2010, Rational quantitative structure-activity relationship (RQSAR) screen for PXR and CAR isoform-specific nuclear receptor ligands., Chem Biol Interact
    Smith CM et al., 2005, Modulation of UDP-glucuronosyltransferase 1A1 in primary human hepatocytes by prototypical inducers., J Biochem Mol Toxicol
    Svecova L et al., 2008, Azole antimycotics differentially affect rifampicin-induced pregnane X receptor-mediated CYP3A4 gene expression., Drug Metab Dispos
    Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol
    Sassano MF et al., 2013, Colloidal aggregation causes inhibition of G protein-coupled receptors., J Med Chem
  • CLOTRIMAZOLE   CYTH2

    Interaction Score: 1.99

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CLOTRIMAZOLE   CFL1

    Interaction Score: 0.5

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16680159


    Sources:
    DTC

  • CLOTRIMAZOLE   NR1I3

    Interaction Score: 0.28

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:

    PMIDs:
    18983136


    Sources:
    DTC

  • CLOTRIMAZOLE   AVPR2

    Interaction Score: 0.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23437772


    Sources:
    DTC

  • CLOTRIMAZOLE   CXCR2

    Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • CLOTRIMAZOLE   JUN

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16680159


    Sources:
    DTC

  • CLOTRIMAZOLE   NR1I2

    Interaction Score: 0.09

    Interaction Types & Directionality:
    activator (activating)
    agonist (activating)

    Interaction Info:

    PMIDs:
    14977870 20869355 15849716 17998298


    Sources:
    PharmGKB

  • CLOTRIMAZOLE   CDK1

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16680159


    Sources:
    DTC

  • CLOTRIMAZOLE   RAPGEF4

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CLOTRIMAZOLE   THPO

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CLOTRIMAZOLE   NPSR1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CLOTRIMAZOLE   TSHR

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CLOTRIMAZOLE   PPARD

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CLOTRIMAZOLE   ADRB2

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CLOTRIMAZOLE   HIF1A

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CLOTRIMAZOLE   HSP90AA1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CLOTRIMAZOLE   GLP1R

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CLOTRIMAZOLE   MAPK1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CLOTRIMAZOLE   CBX1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CLOTRIMAZOLE   TP53

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16680159


    Sources:
    DTC

  • CLOTRIMAZOLE   CYP2C9

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • CLOTRIMAZOLE   CYP2C19

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • CLOTRIMAZOLE   ATXN2

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CLOTRIMAZOLE   KCNH2

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CLOTRIMAZOLE   BAZ2B

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CLOTRIMAZOLE   KDM4A

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CLOTRIMAZOLE   CYP3A4

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • CLOTRIMAZOLE   GMNN

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CLOTRIMAZOLE   CYP1A2

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CLOTRIMAZOLE   CYP2D6

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CLOTRIMAZOLE   AR

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • DTC: CLOTRIMAZOLE

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL104 ChEMBL Drug ID

    Drug Info:

    Publications:
    MacDonald ML et al., 2006, Identifying off-target effects and hidden phenotypes of drugs in human cells., Nat Chem Biol
    Jyrkkärinne J et al., 2008, Insights into ligand-elicited activation of human constitutive androstane receptor based on novel agonists and three-dimensional quantitative structure-activity relationship., J Med Chem
    Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol

  • TTD: Clotrimazole

    • Version: 2020.06.01

    Alternate Names:
    D09GOS TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL104

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

  • PharmGKB: clotrimazole

    • Version: 18-August-2020

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21