DEXTROMETHORPHAN |
DIMETANE-DX |
DEXTROMÉTHORPHANE |
(9S,13S,14S)-3-METHOXY-17-METHYLMORPHINAN |
D-METHORPHAN |
DM |
DEXTROMETHORPHANUM |
DEXTROMETHORFAN |
(+)-DEXTROMETHORPHAN |
DELTA-METHORPHAN |
DEXTROMETORFANO |
DEX |
chembl:CHEMBL52440 |
rxcui:3289 |
rxcui:236146 |
chemidplus:125-71-3 |
pubchem.compound:5360696 |
drugbank:00514 |
Drug Categories | antitussive agents |
Drug Class | antitussive agents |
Year of Approval | approved before 1982 |
FDA Approval | Approved before 1982 |
Drug Class | small molecule |
Drug Indications | Antitussive Agents |
Drug Indications | analgesic |
FDA Approval | approved |
Drug Class | Small molecule |
Drug Indications | antitussive agent |
Drug Categories | anticholinergic agents |
Drug Categories | antidepressive agents |
Drug Categories | central nervous system depressants |
Drug Categories | combined inhibitors of serotonin/norepinephrine reuptake |
Drug Categories | cough and cold preparations |
Drug Categories | cytochrome p-450 cyp3a substrates |
Drug Categories | cytochrome p-450 cyp3a5 substrates |
Drug Categories | cytochrome p-450 cyp3a7 substrates |
Drug Categories | cytochrome p-450 substrates |
Drug Categories | expectorants |
Drug Categories | heterocyclic compounds, fused-ring |
Drug Categories | narcotics |
Drug Categories | nicotinic antagonists |
Drug Categories | opium alkaloids and derivatives |
Drug Categories | serotonergic drugs shown to increase risk of serotonin syndrome |
Drug Categories | serotonin agents |
Drug Categories | sigma-1 agonist |
Drug Categories | sigma-1 receptor agonists |
Drug Categories | uncompetitive n-methyl-d-aspartate receptor antagonist |
Drug Categories | uncompetitive nmda receptor antagonists |
agonist (activating) |
Details of the Assay for Interaction | Sigma receptor cloned from Jurkat cells, identified as SIGMAR1. |
Specific Action of the Ligand | Agonist |
Endogenous Drug? | False |
blocker (inhibitory) |
Details of the Assay for Interaction | Measured <i>vs.</i> exogenously expressed zeta1/epsilon3 (<i>GRIN1/GRIN2C</i>) subunits, at pH 6.9 |
Specific Action of the Ligand | None |
Endogenous Drug? | False |
DEXTROMETHORPHAN | DrugBank Drug Name |
125-71-3 | CAS Number |
12 Hour Cough Relief | Drug Brand |
Drug Type | small molecule |
Drug Groups | approved |
Drug Categories | alkaloids |
DEXTROMETHORPHAN | Primary Drug Name |
Year of Approval | approved before 1982 |
Drug Class | antitussive agents |
Drug Indications | antitussive agent |
Drug Class | Small molecule |
FDA Approval | approved |
CHEMBL52440 | ChEMBL Drug ID |
C423 | NCI drug code |
D09OBB | TTD Drug ID |
DEXTROMETHORPHAN | GuideToPharmacology Ligand Name |