DEXTROMETHORPHAN Drug Record
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DEXTROMETHORPHAN chembl:CHEMBL52440 Approved
Alternate Names:
DEXTROMETHORPHAN DIMETANE-DX DEXTROMÉTHORPHANE (9S,13S,14S)-3-METHOXY-17-METHYLMORPHINAN D-METHORPHAN DM DEXTROMETHORPHANUM DEXTROMETHORFAN (+)-DEXTROMETHORPHAN DELTA-METHORPHAN DEXTROMETORFANO DEX chembl:CHEMBL52440 rxcui:3289 rxcui:236146 chemidplus:125-71-3 pubchem.compound:5360696 drugbank:00514 Drug Info:
Drug Categories antitussive agents Drug Class antitussive agents Year of Approval approved before 1982 FDA Approval Approved before 1982 Drug Class small molecule Drug Indications Antitussive Agents Drug Indications analgesic FDA Approval approved Drug Class Small molecule Drug Indications antitussive agent Drug Categories anticholinergic agents Drug Categories antidepressive agents Drug Categories central nervous system depressants Drug Categories combined inhibitors of serotonin/norepinephrine reuptake Drug Categories cough and cold preparations Drug Categories cytochrome p-450 cyp3a substrates Drug Categories cytochrome p-450 cyp3a5 substrates Drug Categories cytochrome p-450 cyp3a7 substrates Drug Categories cytochrome p-450 substrates Drug Categories expectorants Drug Categories heterocyclic compounds, fused-ring Drug Categories narcotics Drug Categories nicotinic antagonists Drug Categories opium alkaloids and derivatives Drug Categories serotonergic drugs shown to increase risk of serotonin syndrome Drug Categories serotonin agents Drug Categories sigma-1 agonist Drug Categories sigma-1 receptor agonists Drug Categories uncompetitive n-methyl-d-aspartate receptor antagonist Drug Categories uncompetitive nmda receptor antagonists Publications:
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Interaction Score: 1.89
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Interaction Score: 1.89
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Interaction Score: 1.55
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Details of the Assay for Interaction Sigma receptor cloned from Jurkat cells, identified as SIGMAR1. Specific Action of the Ligand Agonist Endogenous Drug? False -
Interaction Score: 1.42
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Interaction Score: 0.57
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Interaction Score: 0.53
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Interaction Score: 0.32
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Interaction Score: 0.21
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Interaction Score: 0.19
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Interaction Score: 0.16
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Interaction Score: 0.1
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Interaction Score: 0.09
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Interaction Score: 0.08
Interaction Types & Directionality:
blocker (inhibitory) Interaction Info:
Details of the Assay for Interaction Measured <i>vs.</i> exogenously expressed zeta1/epsilon3 (<i>GRIN1/GRIN2C</i>) subunits, at pH 6.9 Specific Action of the Ligand None Endogenous Drug? False -
Interaction Score: 0.07
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Interaction Score: 0.07
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Interaction Score: 0.05
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Interaction Score: 0.04
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Interaction Score: 0.02
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Interaction Score: 0.01
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Interaction Score: 0.01
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Alternate Names:
DEXTROMETHORPHAN DrugBank Drug Name 125-71-3 CAS Number 12 Hour Cough Relief Drug Brand Drug Info:
Drug Type small molecule Drug Groups approved Drug Categories alkaloids Publications:
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- Version: 01-August-2011
Alternate Names:
DEXTROMETHORPHAN Primary Drug Name Drug Info:
Year of Approval approved before 1982 Drug Class antitussive agents Publications:
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- Version: January-2014
Alternate Names:
Drug Info:
Drug Indications antitussive agent Drug Class Small molecule FDA Approval approved Publications:
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- Version: 02-September-2020
Alternate Names:
CHEMBL52440 ChEMBL Drug ID Drug Info:
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- Version: 14-September-2017
Alternate Names:
C423 NCI drug code Drug Info:
Publications:
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- Version: 18-August-2020
Alternate Names:
Drug Info:
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- Version: 2020.06.01
Alternate Names:
D09OBB TTD Drug ID Drug Info:
Publications:
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- Version: 29-September-2020
Alternate Names:
DEXTROMETHORPHAN GuideToPharmacology Ligand Name Drug Info:
Publications:
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- Version: ChEMBL_27
Alternate Names:
Drug Info:
Publications:
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- Version: 04-September-2020
Alternate Names:
Drug Info:
Publications: