DGIdb - EMODIN Drug Record

EMODIN chembl:CHEMBL289277

Alternate Names:

EMODIN

Drug Info:

(0 More Sources)

Publications:

Zhang et al., 1998, Tyrosine kinase inhibitors, emodin and its derivative repress HER-2/neu-induced cellular transformation and metastasis-associated properties., Oncogene
Olsen et al., 2007, Emodin negatively affects the phosphoinositide 3-kinase/AKT signalling pathway: a study on its mechanism of action., Int. J. Biochem. Cell Biol.
Sabbah DA et al., 2012, Biological evaluation and docking studies of recently identified inhibitors of phosphoinositide-3-kinases., Bioorg Med Chem Lett
Zhang S et al., 2003, Flavonoids as aryl hydrocarbon receptor agonists/antagonists: effects of structure and cell context., Environ Health Perspect
Srinivas et al., 2004, Antisense blocking of BRCA1 enhances sensitivity to plumbagin but not tamoxifen in BG-1 ovarian cancer cells., Mol. Carcinog.
Yung et al., 2001, Emodin ameliorates glucose-induced morphologic abnormalities and synthesis of transforming growth factor beta1 and fibronectin by human peritoneal mesothelial cells., Perit Dial Int
Han YM et al., 2012, Emodin inhibits migration and invasion of DLD-1 (PRL-3) cells via inhibition of PRL-3 phosphatase activity., Bioorg Med Chem Lett

EMODIN PTP4A3

Interaction Score: 2.38

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22137788

Sources:
DTC
EMODIN TGFB1

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
11887862

Sources:
NCI
EMODIN AHR

Interaction Score: 0.08

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

PMIDs:
14644660

Sources:
DTC
EMODIN PIK3CG

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17018259

Sources:
NCI
EMODIN BRCA1

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14694444

Sources:
NCI
EMODIN CXCL8

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EMODIN PIK3CA

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22212721

Sources:
DTC
EMODIN ERBB2

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9671406

Sources:
NCI
EMODIN THPO

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EMODIN RORC

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EMODIN MPHOSPH8

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EMODIN APEX1

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EMODIN POLB

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EMODIN CBX1

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EMODIN FEN1

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EMODIN TP53

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EMODIN ALDH1A1

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EMODIN CYP2C9

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EMODIN MAPT

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EMODIN KDM4A

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EMODIN CYP2C19

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EMODIN CYP2D6

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EMODIN NFE2L2

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EMODIN AR

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EMODIN EHMT2

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
EMODIN CYP3A4

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

NCI: EMODIN

Version: 14-September-2017

Alternate Names:

C466 NCI drug code

Drug Info:

Publications:

Zhang et al., 1998, Tyrosine kinase inhibitors, emodin and its derivative repress HER-2/neu-induced cellular transformation and metastasis-associated properties., Oncogene

Olsen et al., 2007, Emodin negatively affects the phosphoinositide 3-kinase/AKT signalling pathway: a study on its mechanism of action., Int. J. Biochem. Cell Biol.

Yung et al., 2001, Emodin ameliorates glucose-induced morphologic abnormalities and synthesis of transforming growth factor beta1 and fibronectin by human peritoneal mesothelial cells., Perit Dial Int

DTC: EMODIN

Version: 02-September-2020

Alternate Names:

CHEMBL289277 ChEMBL Drug ID

Drug Info:

Publications:

Sabbah DA et al., 2012, Biological evaluation and docking studies of recently identified inhibitors of phosphoinositide-3-kinases., Bioorg Med Chem Lett

Han YM et al., 2012, Emodin inhibits migration and invasion of DLD-1 (PRL-3) cells via inhibition of PRL-3 phosphatase activity., Bioorg Med Chem Lett

ChemblDrugs: chembl:CHEMBL289277
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

EMODIN Drug Record

EMODIN chembl:CHEMBL289277

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22137788

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 11887862

Sources: NCI

Interaction Types & Directionality: agonist (activating)

Interaction Info:

PMIDs: 14644660

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 17018259

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 14694444

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22212721

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9671406

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Interaction Types & Directionality:

n/a

PMIDs:
22137788

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
11887862

Sources:
NCI

Interaction Types & Directionality:

agonist (activating)

PMIDs:
14644660

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
17018259

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
14694444

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
22212721

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
9671406

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Alternate Names:

C466 NCI drug code

Alternate Names:

CHEMBL289277 ChEMBL Drug ID